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In connection with the publication in Bali Med J 2016, Volume 5, Number 2: 25-29, entitled "Intra-Arterial Heparin Flushing Increases Manual Muscle Test – Medical Research Councils (MMT-MRC) Score in Chronic Ischemic Stroke Patient " Machfoed, Moh Hasan; Usman, Fritz Sumantri; Barus, Jimmy; Wreksoatmodjo, Budi Riyanto; Gunawan, Dede; Bintang, Andi Kurnia; Tugasworo, Dodik; Subroto, Gatot; Lamsudin, Rusdi; Harsono, H.; Sulthan, Riza
BALI MEDICAL JOURNAL Vol 5 No 2 (2016)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (425.667 KB)

Abstract

In connection with the publication in Bali Med J 2016, Volume 5, Number 2: 25-29,entitled "Intra-Arterial Heparin Flushing Increases Manual Muscle Test – Medical Research Councils (MMT-MRC) Score in Chronic Ischemic Stroke Patient ", herewith, please allow us to do reviews of the study discussion. By assessing the discussion, it can be proved whether there are references that support the results of study.
Multidimensional Clinical Challenges in a Female with Chronic Epilepsy on Phenytoin: A Case Report: Nurulita, Syafira Laila; Lamsudin, Rusdi
Ahmad Dahlan Medical Journal Vol. 6 No. 2 (2025): November 2025
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/admj.v6i2.14276

Abstract

Epilepsy is a long-standing neurological disorder defined by recurrent, unprovoked seizures, affecting more than 50 million individuals globally and influencing physical, mental, and social aspects of life. Continuous administration of antiepileptic drugs (AEDs) such as phenytoin is a common therapeutic strategy; however, prolonged use may result in adverse effects that complicate treatment. This case report describes a 40-year-old woman with epilepsy since the age of four, presenting with recurrent seizures, impaired memory, headaches, and sexual dysfunction. Her most recent event was an absence seizure accompanied by upward eye deviation and tongue biting. Electroencephalography (EEG) demonstrated generalized spike-and-wave patterns. The patient was treated with phenytoin and folic acid, with the recent addition of clobazam, leading to favorable outcomes, including reduced seizure frequency, improved sleep, and diminished anxiety and dizziness. A persistent reduction in libido, first noted during adolescence, was suspected to be associated with long-term phenytoin use. Additionally, dental problems such as caries and tooth impaction were believed to worsen headache intensity. This case emphasizes the need for a comprehensive approach to epilepsy care, considering psychological conditions, cognitive impairment, and oral health. Prompt recognition of AED-related side effects and individualized treatment planning are essential to optimize patient outcomes.