Leonny Dwi Rizkita
Departemen Farmakologi, Fakultas Kedokteran, Universitas Ahmad Dahlan, Yogyakarta, Indonesia

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Potensi Aktivitas Antibakterial Ekstrak Bunga Telang (Clitoria Ternatea): Potential Antibacterial Activity of Telang Flower Extract (Clitoria Ternatea) Muflihah Rizkawati; Leonny Dwi Rizkita
Jurnal Sains dan Kesehatan Vol. 5 No. 1 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i1.1512

Abstract

High burden rate of antimicrobial resistance (AMR) worldwide encourages for more new studies of therapeutic strategies to minimize the further morbidities and mortalities, especially in country with heavy prevalence of infection disease. One of the alternative approach is through the nature. Butterfly pea (Clitoria ternatea) or Asian Pigeonwing is indigenous decorative plant commonly found in tropical region of the world, such as Pacific Asia, South America and Madagascar. The bright purple colour is notably utilized as natural food colouring in many Asian cuisine. The particular plant has been used for years as medicinal plant in various preparations, mostly as decoction for herbal drink/tea. However, scientific analysis to identify the possible health benefits are required to support the vaguely empirical testimony. The antibacterial component owned by butterfly pea plant is not limited by its flower petals only, but also the rest of the body, from the roots to the stem. The extraction process of butterfly pea plant shows myriad of phytochemical compounds with high pharmacological activity, especially as antibacterial against various bacteria such as E. coli and Bacillus cereus. Thus, this review compiles the recent ten years original article reported the antibacterial activities of Clitoria ternatea. Keywords: telang flower, Clitoria ternatea, butterfly pea, antibacterial Abstrak Angka beban global yang diakibatkan oleh kejadian resistensi antimikroba mendorong untuk dilakukan lebih banyak studi yang menelusuri strategi terapi terbaru guna mengurangi penambahan angka morbiditas dan mortalitas terutama pada negara dengan kasus penyakit infeksi yang sering. Salah satu pendekatan yang dapat dilakukan ialah melalui pengamatan terhadap potensi alam. Bunga telang (Clitoria ternatea) merupakan tanaman hias yang banyak ditemukan di negara tropis seperti Asia Pasifik, Amerika Selatan dan Madagaskar. Warna ungu terang yang menjadi khas tanaman tersebut sudah banyak dimanfaatkan sebagai pewarna makanan alami di beragam masakan Asia. Selain itu, tanaman ini juga telah digunakan sejak lama sebagai obat tradisional dalam berbagai sediaan, terutama seduhan rebusan. Namun, pendekatan saintifik diperlukan untuk mendukung pernyataan berbasis empiris. Komponen antimikroba milik bunga telang tidak hanya terbatas pada bagian kelopak bunganya saja namun semua bagian tubuhnya, mulai dari akar hingga batang. Proses ekstraksi tanaman bunga telang menunjukkan komponen fitokimia yang berkhasiat terutama sebagai antimikroba melawan E. coli dan Bacilus cereus. Oleh karena itu, ulasan ini dibuat guna mengkompilasi berbagai penelitian yang melaporkan aktivitas antibakteri Clitoria ternatea. Kata Kunci: Bunga telang, Clitoria ternatea, Antibakteri
The Problematic of Medicinal Plant: Negative effect of Catha Edulis (Khat) Abuse and Its Potential Benefits Muflihah Rizkawati; Ulfatun Nisa; Widhi Astana; Leonny Dwi Rizkita
Jurnal Sains dan Kesehatan Vol. 5 No. 3 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i3.1756

Abstract

Catha edulis (khat), belongs to a group of psychotropic plants, which has an amphetamine-like structure and contains many catin and cation. The plant contains hallucinogenic compounds and known for its calming effect. The excessive catin contained inside the fresh leave of khat could potentially induce a plenty of side effects especially when the leaves are directly consumed and uncooked. The side effects vary according to how long the plant has been consumed, started from local organ disruption to cardiovascular complication such as increased blood pressure to myocardial infarction. In the contrary, positive effects of the composition of khat have also been reported such as anti-inflammatory effect, antidiabetic, anticancer, immunomodulatory and increased improvement in respiratory diseases. Although myriad studies have been conducted to examine the best benefit obtained from the such plant, the legal issue on its utilization is still questionable. Therefore, khat consumption must be maintained with a proper and strong regulation to lessen the negative impacts. However, studies on the potency of khat are still ongoing. The literature review was written based on various books, journals, and search databases in Pubmed, Medline, Cochrane and Google Scholar to show the positive and negative effects of the habit in consuming khat.