Muflihah Rizkawati
Department of Pharmacology, Faculty of Medicine, Universitas Islam Indonesia, Indonesia

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Antiobesity Potential of Butterfly Pea Flower (Clitoria Ternatea): A Literature Review Nur Aini Djunet; Muflihah Rizkawati
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 12, No 2 (2023): September 2023
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v12i2.2670

Abstract

Obesity is a health problem with an increasing prevalence every year in many countries including Indonesia.  Obese patients are at risk for complications related to some non-communicable diseases. The difficulty of losing weight in obese patients is due to low awareness of a good lifestyle, appropriate dietary patterns, and discipline in taking drugs to prevent complications. However, the need for drug consumption takes a long time. The risk of side effects arising from long-term drug use needs to be considered. Using herbal plants as an additional dietary intervention could be a better choice. This review described the benefits of the butterfly pea (Clitoria ternatea) flower as antiobesity. This study is a literature review by searching preceding published articles in Pubmed, ScienceDirect, Cochrane, and Google Scholar journals. The keywords used are (Clitoria ternatea) OR (Bunga Telang) OR (Butterfly pea) AND (Obesity) OR (Antiobesity). Articles are limited by publication period from 2012 to 2022 and then selected based on the criteria. This literature review concluded that the administration of Clitoria ternatea extracts (CTE) can become an alternative antiobesity by inhibiting weight gain, increasing adipose lipolysis, and decreasing the expression of adipogenic and lipogenic proteins.
The Problematic of Medicinal Plant: Negative effect of Catha Edulis (Khat) Abuse and Its Potential Benefits Muflihah Rizkawati; Ulfatun Nisa; Widhi Astana; Leonny Dwi Rizkita
Jurnal Sains dan Kesehatan Vol. 5 No. 3 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i3.1756

Abstract

Catha edulis (khat), belongs to a group of psychotropic plants, which has an amphetamine-like structure and contains many catin and cation. The plant contains hallucinogenic compounds and known for its calming effect. The excessive catin contained inside the fresh leave of khat could potentially induce a plenty of side effects especially when the leaves are directly consumed and uncooked. The side effects vary according to how long the plant has been consumed, started from local organ disruption to cardiovascular complication such as increased blood pressure to myocardial infarction. In the contrary, positive effects of the composition of khat have also been reported such as anti-inflammatory effect, antidiabetic, anticancer, immunomodulatory and increased improvement in respiratory diseases. Although myriad studies have been conducted to examine the best benefit obtained from the such plant, the legal issue on its utilization is still questionable. Therefore, khat consumption must be maintained with a proper and strong regulation to lessen the negative impacts. However, studies on the potency of khat are still ongoing. The literature review was written based on various books, journals, and search databases in Pubmed, Medline, Cochrane and Google Scholar to show the positive and negative effects of the habit in consuming khat.