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All Journal Amerta Nutrition Jurnal Ilmu Kedokteran dan Kesehatan PREPOTIF : Jurnal Kesehatan Masyarakat Heart Science Journal
Saskia Dyah Handari
Departmen Of Cardiology And Vascular Medicine, Faculty Of Medicine, Universitas Ciputra, Surabaya.
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Journal : Heart Science Journal

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Coronary CT Angiography for Coronary Artery Disease: The Current Status and Future Challenges Saskia Dyah Handari
Heart Science Journal Vol 4, No 2 (2023): Dealing with the Complexity of the Wide Spectrum of Cardiovascular Disease
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2023.004.02.1

Abstract

Coronary computed tomographic angiography, often known as CCTA, is quickly becoming the diagnostic technique of choice for determining the existence of coronary artery disease (CAD). In the future, CCTA may play an essential part as a "one-stop shop" in the screening, diagnosis, decision making, and treatment planning processes. Plaque burden, high-risk plaque, non-invasive angiography, perfusion with hyperemia, fractional flow reserve (FFR), percent of myocardium at risk, inflammation, myocardial scar, wall motion analysis, and risk scores are some of the many measures that are utilized.
Correlation Between Jakarta Cardiovascular Score and Coronary Artery Calcium Score in High-Risk Women at Siloam Hospital Surabaya, Indonesia, 2020-2021. Imam Mi'raj Suprayoga; Saskia Dyah Handari
Heart Science Journal Vol 4, No 2 (2023): Dealing with the Complexity of the Wide Spectrum of Cardiovascular Disease
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2023.004.02.3

Abstract

Background: Coronary Artery Calcium Score (CAC) is an indicator of atherosclerosis and could be used as a reliable noninvasive assessment of coronary artery disease. The Jakarta Cardiovascular Assessment (JAKVAS) is a modified Framingham risk score based on the Indonesian population targeted for developing countries. This study was aimed todetermine the correlation between Jakarta Cardiovascular Score and Coronary Artery Calcium Score in High-Risk Women in Surabaya, Indonesia, in 2020-2021. Method: This study was a retrospective study looking for a correlation between JAKVAS and CAC, with data taken from the medical records of Siloam Hospital Surabaya from 2020-2021. Result: The association between JAKVAS and CAC risk stratification was significant (P < 0.05). Conclusion: Theabsence of CAC is related to a lower risk of cardiovascular events (JAKVAS) than CAC > 0 in high-risk women.
Navigating Complex Cardiovascular Pathologies: A Case Report on Aortic Arch Replacement in a Middle-Aged Male with Stanford A DeBakey I Aortic Dissection Handari, Saskia Dyah; Firdaus, Muhammad; Sembiring, Yan Efrata
Heart Science Journal Vol. 5 No. 2 (2024): Challenges in the Management of Congenital Heart and Structural Heart Diseases
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub/hsj.2024.005.02.14

Abstract

Background: Aorta dissection is characterized by the presence of an intimal tear, which permits the passage of blood through the tear and into the aorta media. This process leads to the separation of the intimal and the formation of a dissection flap, representing the true lumen and a newly formed false lumens. The incidence of aortic dissection varies between 0.2% and 0.8%. Management of acute aortic standford A aortic dissection primarily involves invasive surgical procedures.Case presentation: A middle-aged male patient, aged 40, who possesses risk factors including uncontrolled hypertension and obesity, arrived to the emergency room with symptoms of chest pain. He described the pain as tearing in nature and said that it radiated towards the abdominal. The examination findings included a blood pressure reading of 255/143, a widened mediastinum and cardiomegaly observed on the chest X-ray, a slight elevation in Hs-Troponin levels, and the presence of sinus rhythm with left ventricular hypertrophy. He underwent CT scan, which demonstrated the presence of an aortic dissection extending from the ascending to descending aorta, with no associated damage to the aortic valve from echocardiography. He was diagnosed with Standford A DeBakey I Aortic dissection and underwent preference replacement of the aortic arch and elephant trunk implantation instead of Bentall procedure.Conclusion: The surgical and perioperative methods employed may differ based on the specific clinical presentation and the nature of the aortic disease. Because there was no involvement of the aortic valve, we performed total aortic arch replacement and elephant trunk procedure over the Bentall procedure.
Cardiac imaging in cardiovascular complications due to COVID-19 Galuh, Lukitasari Ayu; Sargowo, Djanggan; Satrijo, Budi; Handari, Saskia Dyah; Rahimah, Anna Fuji
Heart Science Journal Vol. 5 No. 4 (2024): The Current Perspective About Cardiometabolic Disease
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2024.005.04.6

Abstract

Cardiovascular complications are a common manifestation of acute phase and chronic phase of coronavirus disease 2019 (COVID-19) infection. Complications include cardiomyopathy, myocardial infarction, arrhythmias, heart failure, and deep venous thrombosis. Imaging is widely used in patients with suspected myocardial injury or myocarditis. Because of its availability and portability, transthoracic echocardiography (TTE) is used as the initial imaging modality in patients with suspected COVID-19 myocarditis. Echocardiographic studies performed on patients with suspected or confirmed COVID-19 should be as focused as necessary to obtain diagnostic views but should also be comprehensive enough to avoid the need to return for additional images. Following COVID-19 infection, a variety of persistent respiratory, neurological, cardiovascular, and other symptoms can persist for weeks, months, or even years. A cardiac examination and any resulting abnormalities in the structure and function of the heart may occasionally last for several months following a COVID-19 diagnosis. This is referred to as long  COVID syndrome. Cardiac magnetic resonance (CMR) imaging has often been used clinically to complement echocardiography, particularly tissue characterization imaging which demonstrated subclinical myocardial edema with or without fibrosis in patients recovered from illness.
The Effect of Exercise Training as Adjuvant Treatment on Functional Capacity in Congenital Heart Disease with Negative Vaso Reactivity Test Pulmonary Hypertension Patient at Saiful Anwar Hospital Malang Pratiwi, Irma Kamelia; Martini, Heny; Tjahjono, Cholid Tri; Anjarwani, Setyasih; Handari, Saskia Dyah
Heart Science Journal Vol. 4 No. 3 (2023): The Essensial Role of the Metabolic Syndrome in the Development of Cardiovascul
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2023.004.03.3

Abstract

BackgroundPulmonary hypertension associated with congenital heart disease (CHD) is an important subgroup that accounts for approximately 11% of all patients with PAH. Physical limitations are one of the main symptoms of hemodynamic changes in patients with PH. Objective This study aimed to evaluate the effect of physical exercise therapy for 12 weeks as an additional therapy with PDE-5 inhibitors on the functional capacity of patients with Congenital Heart Disease accompanied by Pulmonary Artery Hypertension (CHD – PH). MethodThis research was an analytic experimental study with a prospective cohort research method. This study used data sources obtained from medical records to adjust subjects based on inclusion and exclusion criteria, initial cardiac training test examination data was carried out at IPJT in patients selected as subjects. The patient's clinical outcomes were followed in the next 12 weeks. ResultThis research was conducted on 16 samples divided into two groups, namely the control and study groups. The evaluation after 12 weeks found that there was an increase in mileage as measured through the 6MWT submaximal test and a better duration of physical activity in the study group tested through the Endurance Shuttle Walk Test (ESWT). This is consistent with the effect of physical exercise, which suppresses systemic inflammation and causes vasodilation, thereby increasing oxygen delivery to the tissues. This causes more optimal aerobic metabolism and reduces lactate production. So that the patient did not quickly feel tired during activities. However, there was no significant increase in the Incremental Shuttle Walk Test. This could be due to the relatively short training duration of 12 weeks. Conclusion A positive correlation exists between physical exercise and increased functional capacity of patients with CHD who were evaluated using 6MWT and ESWT.
Giant left coronary artery with coronary cameral fistula in significant coronary artery disease : A case report Caesario, Fahreza; Handari, Saskia Dyah
Heart Science Journal Vol. 6 No. 2 (2025): The Complexity in the Management of Heart Rhythm Disorder
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.02.18

Abstract

Background : Coronary Artery Fistula are coronary anomalies that affected populations with rare incidences. Concomitant disease such as coronary artery disease (CAD) may be occurred in CAF and causing complexity to its management. Objective : This case presentation aimed to describe the characteristic, diagnosis and management of CAF with concomitant disease such as CAD. Case Presentation : We will discuss A 56 year old male admitted as an outpatient with left sided chest pain as the chief complain. The chest pain was described as ischemic chest pain with supporting examination lead to the suspicion of coronary artery disease.  Contrast enhanced CT Angiography examination was planned for diagnosing Coronary Artery Disease in this patient. 3D reconstruction of the coronary tree revealed giant LAD (Diameter 6.5 – 7mm) with normal size of LCx and Dominant RCA. The distal LAD was communicating with the LV cavity through big coronary fistulae. Impression of significant stenosis showed in the proximal RCA described as mixed plaque causing >70% Stenosis. PCI of the RCA and CAF Closure management was proposed but there was a disagreement of further coronary intervention from the patient. Conclusion : CAF in concomitant CAD is a complex structural disease with challenging management. Combination of surgical procedure was the recommendation for the management of this case.
Coronary plaque assessment by coronary computed tomography angiography Indrihapsari, Pratiwi; Handari, Saskia Dyah
Heart Science Journal Vol. 6 No. 3 (2025): Advancements in Cardiac Imaging : Unlocking New Perspectives on the Heart Visua
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.03.2

Abstract

Coronary computed tomography angiography (CCTA) is a widely used non-invasive diagnostic technique in medical practice. It effectively detects, quantifies, and characterizes coronary artery plaques. With advancements in CCTA imaging, the quantity and quality of atherosclerotic plaques can now be accurately evaluated. This technique is commonly utilized to rule out the possibility of coronary artery disease and precisely assess how the condition impacts the coronary vessels. CCTA is a valuable diagnostic tool that can help identify high-risk plaque features and recommend appropriate treatment measures. By comparing morphological aspects of stable lesions with those of susceptible plaques, CCTA can help identify characteristics such as the napkin-ring sign, low CT attenuation, positive remodeling, significant plaque volume, and spotty calcification, which have been linked to an increased risk of acute coronary syndrome. To standardize the reporting of patients who undergo CCTA and guide probable following actions in patient care, the Coronary Artery Disease Reporting and Data System (CAD-RADS) was created. This system ensures that patient reports are consistent, accurate, and valuable for guiding appropriate treatment and care.
Multimodality imaging in evaluation of cardiac masses Sihotang, Fransiska Anggreni; Handari, Saskia Dyah
Heart Science Journal Vol. 6 No. 3 (2025): Advancements in Cardiac Imaging : Unlocking New Perspectives on the Heart Visua
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.03.8

Abstract

Cardiac masses are infrequently encountered in routine cardiology practice but often pose as a diagnostic challenge. Cardiac masses can be categorised as either neoplastic (benign and malignant) or non-neoplastic, and as either primary or secondary. The prognosis is contingent upon the identification of the mass, as treatment choices vary significantly. Histopathology remains the most dependable approach for diagnosing any cardiac tumour. Nevertheless, given its invasive characteristics, cardiac imaging plays a crucial role in diagnosing cardiac masses. The emergence of new imaging tools necessitates a multimodality strategy to assess intracardiac masses. This approach is crucial for non-invasive evaluation before considering surgical planning or oncological treatment. This article aims to compare the different imaging techniques, particularly echocardiography, cardiovascular magnetic resonance, cardiac computed tomography, and nuclear imaging, in terms of their clinical applications in the evaluation of cardiac masses and to determine distinctive features on these modalities for the most prevalent intracardiac masses.
Multi-modality cardiac imaging in aorta and aortic valve from evaluation to post treatment Suprapta, Aloysius Yuwono; Handari, Saskia Dyah
Heart Science Journal Vol. 6 No. 3 (2025): Advancements in Cardiac Imaging : Unlocking New Perspectives on the Heart Visua
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.03.4

Abstract

Aorta and aortic valve disease are crucial but usually found unintentionally while doing imaging evaluation. Genetic and non-genetical issues can be the source of the disease. Proper evaluation using multimodality of imaging can give an early diagnosis and proper treatment according to recent situation.  Aortic disease and aortic valve disease can result from genetic and non-genetic problems. Echocardiography (transthoracic or transesophageal) can be the first modality to evaluate this disease. Further modalities (computed tomography angiography, magnetic resonance imaging, and positron electromagnetic) can be used as supporting data to make more accurate analyses for diagnosis and evaluation post-treatment. Although they give more accurate images, there are some limitations in each modality. Knowing the benefits and limitations of each modality can make better use of the tools. Multimodality imaging is enhancing in detection of aortic disease and aortic valve disease. Understanding the benefits and limits of each imaging technique is essential for determining the best modality
Non-invasive multimodality cardiac stress test imaging: Role of echocardiography, cardiac computed tomography, cardiac magnetic resonance, and nuclear medicine Kahadi, Cik; Handari, Saskia Dyah
Heart Science Journal Vol. 6 No. 3 (2025): Advancements in Cardiac Imaging : Unlocking New Perspectives on the Heart Visua
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.03.3

Abstract

Coronary artery disease, or CAD, is the major cause of mortality and morbidity globally, with significant socioeconomic impact. Based on European Society of Cardiology or ESC guidelines in Chronic Coronary Syndrome (CCS), multimodality imaging strategies are highly suggested in evaluating the patient who suspected CAD. Non-invasive imaging modalities can assess the anatomy of coronary artery by using Coronary Computed Tomography Angiography (CCTA) or assess functional stress testing with inducible myocardial ischemia by using Stress Echocardiography (SE), Myocardial CT Perfusion (CTP), Cardiac Magnetic Resonance (CMR), Single Photon Emission Computed Tomography (SPECT), or Positron Emission Tomography (PET). Nowadays, it’s important to recognize the limitations and capabilities of each imaging method, especially before selecting a functional testing focused on ischemia compared to an anatomy of coronary imaging. This paper describes an overview of non-invasive imaging modalities for the general diagnosis of CAD patients. Non-invasive multimodality cardiac stress test imaging is enhancing the diagnosis of significant stenosis of the coronary artery. Understanding the benefits and limits of each imaging is essential for determining the best modality we used.
Co-Authors Adhitya Ginting Agung, Purwakaning Purnomo Anjarwani, Setyasih Antonius Yansen Suryadarma Caesario, Fahreza Cholid Tri Tjahjono Cholid Tri Tjahjono Christine, Catarina Lilian Damayanti, Ni Nyoman Rere Dion, Aldy Djanggan Sargowo Firdaus, Achmad Jauhar Fransiska Anggreni Sihotang Galuh, Lukitasari Ayu Hebert Adrianto Imam Mi&#039;raj Suprayoga Indra Prasetya Indrihapsari, Pratiwi Jefri, Wilhelmus Kahadi, Cik Kusuma, Irwin Prijatna Martini, Heny Mirna Rahmasari Muhammad Firdaus Nidom, Astria Novitasari Panggabean, Ronald Torang Marsahala Pratiwi, Irma Kamelia Putri, Firda Aulia Rahimah, Anna Fuji Satrijo, Budi Sembiring, Yan Efrata Suprapta, Aloysius Yuwono Victor Kurniawan Yuwono Vori, Ira Yasa, Oka Suputra Yurike Dhika Adhela