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Clinical Benefits of Ketorolac in Postoperative Pain Control Management: A Comprehensive Review Noer, Tjandrakirana M Sjaifullah; Pribadi, Florence; Dion, Aldy
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Vol.10 No.1 Mei 2024
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v10i1.14909

Abstract

Pain accounts for about 70% of visits to emergency rooms, approximately 80% of surgical patients experience acute postoperative pain, more than 38% of patients are readmitted following surgery due to severe pain. Up to 77% of post surgical patients received insufficient pain treatment, following treatment 71% of patients reported continuing to experience pain and 80% said they were still experiencing moderate to severe pain. Previous studies conducted both domestically and internationally have demonstrated the benefits of ketorolac and its usefulness in managing postoperative pain. This article's goal is to provide a comprehensive understanding of the potential of ketorolac as a pharmacological agent in the management of post-operative pain. A narrative review method was employed, utilizing research articles and international guidelines to gather literature. Around 230 libraries were found to meet the criteria and studied, 27 libraries were used in order to create this article. Ketorolac has a good safety profile and there are a few contraindications in patients that clinicians must be aware. Studies suggest that administering ketorolac within two hours after surgery for a treatment duration of two to five days. Numerous studies have demonstrated the potential of ketorolac in the therapy of postoperative pain.
Elaboration Of Secondary Prevention Measures For Individuals With Cystine Metabolic Disorder To Reduce The Risk Of Urolithiasis : A Critical Review Dion, Aldy; Christine, Catarina Lilian; Adrianto, Hebert
Jurnal EduHealth Vol. 15 No. 02 (2024): Jurnal eduHealt, Edition April - June , 2024
Publisher : Sean Institute

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Abstract

Urolithiasis in Asia affects about 1% - 19.1% of the population. Urolithiasis disease in young patients has a significant morbidity rate. Basic metabolic disorder such as cystinuria are often associated with urolithiasis. Cystinuria, a congenital cystine metabolism disorder with an incidence ratio of 1:7,000. Cystinuria is a common condition among urolithiasis patients. The paper aims to summarize recent efforts in secondary prevention to reduce the risk of urolithiasis in cystinuria patients through early detection and prompt treatment. This paper is a narrative review using the literature study method regarding the latest secondary prevention efforts. The library used 24 pieces of literature from research journals and international case reports. Early detection efforts include tracing medical history and urinalysis, followed by an initial diagnosis using PCR, sodium cyanide-nitroprusside test, and attenuated total reflection - fourier transform infrared spectroscopy (ATR-FTIR) can confirm the diagnosis of cystinuria. Thiopronine treatment is currently the main choice, accompanied by a special diet and plenty of water consumption. Another pharmacological therapy (tolvaptan) is still under development and showing promising results. Secondary prevention efforts for cystinuria patients are needed to prevent an adverse urolithiasis event and help reducing morbidity rate.
PEMERIKSAAN DNA BAG1 TOXOPLASMA GONDII DALAM ORGAN HATI AYAM KAMPUNG DI PASAR DI SURABAYA Kusuma, Irwin Prijatna; Adrianto, Hebert; Agung, Purwakaning Purnomo; Yuwono, Victor Kurniawan; Handari, Saskia Dyah; Dion, Aldy; Nidom, Astria Novitasari
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 9 No. 1 (2025): APRIL 2025
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v9i1.44155

Abstract

Manusia dapat terinfeksi oleh T. gondii terutama melalui konsumsi daging mentah/setengah matang yang mengandung kista jaringan T. gondii atau melalui konsumsi makanan dan/atau air yang terkontaminasi ookista. Ayam yang terinfeksi T. gondii dapat berpotensi menularkan T. gondii ke manusia melalui konsumsi daging. Penelitian ini memiliki tujuan melakukan pemeriksaan DNA BAG1 T. gondii dalam organ hati ayam kampung yang diperoleh dari pasar di Surabaya Barat. Metode penelitian dilakukan secara obrservasional di laboratorium. Organ hati ayam kampung diambil dari beberapa pasar tradisional di Surabaya Barat secara kuota sampling. Organ hati dianalisis menggunakan Polymerase chain reaction (PCR) dengan gen BAG1. Panjang produk PCR gen BAG1 adalah 470 bp. Data penelitian dianalisis secara deskriptif dengan kategori kategori positif dan hasil negatif. Hasil pemeriksaan keberadaan parasit T. gondii dalam organ hati ayam kampung di Surabaya Barat melalui gen BAG1 adalah 50% sampel positif dan 50% sampel negatif. Perlu upaya skrining ayam yang dijual kepada konsumen dan penerapan PCR menggunakan gen BAG1 T. gondii dapat menjadi langkah awal untuk mencegah penyebaran infeksi toksoplasmosis kepada manusia.
Tracing Mumps in Rural Area: A Clinical Profile of Infected Children and Adolescents in Bulu, Tuban Dion, Aldy; Pribadi, Florence; Dewi, Karina
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 11 No.1 Mei 2025
Publisher : Fakultas Kedokteran Universitas Malikussaleh

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Abstract

Mumps, also known as epidemic parotitis, is a viral infection that affects the salivary glands. This disease commonly occurs among school-aged children and adolescents. According to data from the World Health Organization (WHO), the incidence of mumps in Southeast Asia (excluding Indonesia) reached 8,985 cases in 2022. In Indonesia, the Ministry of Health reported 6,593 cases in 2024. Given these challenges and the high number of cases found in the community, researchers aimed to study the clinical profile of mumps in school-aged children and adolescents in Bulu, Tuban. This research was observational in nature, using a descriptive cross-sectional study design. The findings revealed that male children are at higher risk of contracting mumps, with the highest infection rate observed in the 8-10 year age group. Areas characterized by close-knit living conditions and low immunization coverage reported a higher incidence of mumps. The most common complaint that led patients to seek medical care was cheek pain. Additionally, a significant number of mumps patients were found to be underweight. The most frequently administered treatment involved a combination of analgesic and vitamin.
Hubungan Antara Stres Dan Risiko Kardiovaskular Berdasar Jakvas Scoring System: Studi Pada Ojek Online Di Surabaya Handari, Saskia Dyah; Ginting, Adhitya; Panggabean, Ronald Torang Marsahala; Adrianto, Hebert; Suryadarma, Antonius Yansen; Christine, Catarina Lilian; Dion, Aldy; Jefri, Wilhelmus; Putri, Firda Aulia; Damayanti, Ni Nyoman Rere; Yasa, Oka Suputra
Jurnal Ilmu Kedokteran dan Kesehatan Vol 12, No 11 (2025): Volume 12 Nomor 11
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v12i11.20686

Abstract

Stres kerja merupakan salah satu faktor risiko utama yang dapat memengaruhi kesehatan kardiovaskular. Salah satu profesi pekerjaan yang berisiko stres adalah pengemudi ojek online. Penelitian memiliki tujuan untuk melihat hubungan tingkat stres dengan skor JAKVAS. Penelitian ini adalah penelitian observasional analitik dengan pendekatan cross sectional. Responden adalah 75 orang sopir transportasi online laki-laki yang mengendarai sepeda motor dari 5 wilayah Surabaya, yang diambil dengan accidental sampling. Pengukuran tingkat stress menggunakan kuesioner Perceived Stress Scale (PSS). Pengukuran risiko kardiovaskular menggunakan Jakarta Cardiovascular Score (JAKVAS). Data dianalisis statistik dengan menggunakan program jamovi, menggunakan statistik deskriptif dan uji chi square. Hasil penelitian didapatkan skor JAKVAS terbanyak adalah kategori high risk (40%),  mayoritas responden memiliki tingkat stress berat (37,3%), tidak terdapat hubungan yang bermakna secara statistik antara tingkat stres dan skor JAKVAS (χ² = 4,396; df = 4; p = 0,355). Meskipun hubungan keduanya tidak signifikan, tingginya proporsi responden dengan risiko kardiovaskular tinggi menegaskan perlunya skrining rutin pada profesi dengan beban kerja tinggi seperti pengemudi ojek online.