Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Jurnal Natural
Muhammad Fajar Islam
Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Papua
Agriculture, Biological Sciences & Forestry Chemistry Mathematics Physics

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
IDENTIFIKASI KERAGAMAN GENETIK DAERAH 3’UTR GEN LDLR PENDUDUK ASLI PAPUA Windasari Windasari; Muhammad Fajar Islam; Achmad Taher
Jurnal Natural Vol. 18 No. 2 (2022): Jurnal Natural
Publisher : FMIPA Universitas Papua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30862/jn.v18i2.218

Abstract

Papua is one of the big islands in Indonesia that has many tribes live within different ecological zones. Different ecological zones may potentially result in genetic diversity of their population. Researches in genetic diversity of the Native Papuans are very rare, mainly in terms of the diversity of the LDLR gen within the 3’UTR. The research aimed to identify the genetic diversity of the LDLR gen of the indigenous people of Papua within the 3’UTR. Four steps were performed in the research, namely DNA extraction, amplification, electrophoresis, and sequencing. Two SNPs within the 3’UTR’s were identified with a nucleotide diversity (π) of 0.00177. The identified SNPs are at *52, that is G>A and at *504, that is G>A. The observed haplotypes are GG and AA with a diversity of 0.533± 0.172.
SNP PADA GEN KEMOKIN C-C MOTIF LIGAN 7 (CCL7) PENDERITA STROKE DI KABUPATEN MANOKWARI Muti Dornita Simamora; Muhammad Fajar Islam; Achmad Taher
Jurnal Natural Vol. 19 No. 2 (2023): Jurnal Natural
Publisher : FMIPA Universitas Papua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30862/jn.v19i2.245

Abstract

Chemokines are key components in the development of chronic disease. Chemokine C-C motif ligan 7 (CCL7) is one of the chemokines believed to be associated with the pathology of atherosclerosis that causes stroke. CCL7 may play a role in inflammatory events by attracting macrophages and moncytes to further amplify inflammatory processes and contribute to atherosclerosis progression. Common Genetic variation in CCL7 gene has been associated with atherosclerosis progress, so the main objective of this study was identification of polymorphism of CCL7 gene in stroke patients. Five blood samples were taken from five patients suffering from stroke. The DNA of the blood samples were extracted, amplified its CCL7 gene, and sequenced. The results showed a sequence of 1151 bp consisting of regulator, exon 1, intron and exon 2. One polymorphic sites were found in the intron 1 region, at position 1447. The SNP genotype identified was TC.
Co-Authors Achmad Taher Achmad Taher Muti Dornita Simamora Windasari Windasari