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Harris Utama
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Health Professions Medicine & Pharmacology Public Health

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Multisystem Inflammatory Syndrome in Children: A Review Chandni P. Daryanani; Theresia Monica Rahardjo; Harris Utama; Angga Trie Buana; Eaufira Mereditha Pasaribu; Euodia Eunike
Medical Clinical Update Vol. 2 No. 1 (2023): February
Publisher : Rumah Sakit Unggul Karsa Medika

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (4428.78 KB) | DOI: 10.58376/mcu.v2i1.26

Abstract

Pediatric inflammatory multisystem syndrome, temporally associated with SARS-CoV-2 (PIMS-TS) or multisystem inflammatory syndrome in children (MIS-C) is a condition identified recently. Children who were previously healthy may experience cardiac, neurological, respiratory, gastrointestinal, and dermatological dysfunction. Majority of patients (73%) require intensive care treatment, and more than half (56%) of patients arrive in shock. Different management are used for MIS-C patients, but they all primarily focus on immunomodulatory drugs such as IVIG and glucocorticoids as initial therapy. Biologic agents like anakinra, tocilizumab, and infliximab should be intensified when the patients are resistant to IVIG and glucocorticoids.
Co-Authors Angga Trie Buana Chandni P. Daryanani Eaufira Mereditha Pasaribu Euodia Eunike Theresia Monica Rahardjo