Chandni P. Daryanani
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Multisystem Inflammatory Syndrome in Children: A Review Chandni P. Daryanani; Theresia Monica Rahardjo; Harris Utama; Angga Trie Buana; Eaufira Mereditha Pasaribu; Euodia Eunike
Medical Clinical Update Vol. 2 No. 1 (2023): February
Publisher : Rumah Sakit Unggul Karsa Medika

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (4428.78 KB) | DOI: 10.58376/mcu.v2i1.26

Abstract

Pediatric inflammatory multisystem syndrome, temporally associated with SARS-CoV-2 (PIMS-TS) or multisystem inflammatory syndrome in children (MIS-C) is a condition identified recently. Children who were previously healthy may experience cardiac, neurological, respiratory, gastrointestinal, and dermatological dysfunction. Majority of patients (73%) require intensive care treatment, and more than half (56%) of patients arrive in shock. Different management are used for MIS-C patients, but they all primarily focus on immunomodulatory drugs such as IVIG and glucocorticoids as initial therapy. Biologic agents like anakinra, tocilizumab, and infliximab should be intensified when the patients are resistant to IVIG and glucocorticoids.
The Impact of Childhood Malnutrition: A Case Report Chandni P. Daryanani; Bryan Kohen; Ellen G White Br Manik; Joseph Gerard Un Nahak; Xena Syafira
Medical Clinical Update Vol. 2 No. 1 (2023): February
Publisher : Rumah Sakit Unggul Karsa Medika

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3214.354 KB) | DOI: 10.58376/mcu.v2i1.31

Abstract

Childhood malnutrition is a widespread issue in low-income and middle-income countries, which increases the occurrence and severity of infections, including pneumonia. The impaired immune function of malnourished children contributes significantly to the heightened incidence and severity of infections, caused by limited production or reduced functional capacity of immune system cells
Caesarean Section as A Prevention of Intrapartum Transmission in Pregnant Woman with Syphilis: A: Case Report Chandni P. Daryanani; Aloysius Suryawan; Theresia Monica Rahardjo; Apriani Lam; Maxzillion Sky Kasnadi; Nadya Ariella; Stefanie Sumartono; Syifa Navisah
Medical Clinical Update Vol. 3 No. 1 (2023): June
Publisher : Rumah Sakit Unggul Karsa Medika

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Abstract

Syphilis is an infectious disease caused by spirochete bacterium Treponema pallidum. Most of the new case of syphilis occur in men, but there is a tendency of increasing infection rate in reproductive-aged women, with the highest rates observed in 20-24 years old. Syphilis can be transmitted by sexual intercourse, blood products transfusion, or transplacental known as congenital syphilis and during delivery process as intrapartum transmission. Syphilis is a relapsing and remitting disease with early and late stages. Congenital syphilis is caused by foetal infection of Treponema pallidum, transmission mostly occurs transplacental, and it may occur at any time during gestation.
Henoch-Schonlein Purpura in 14 years-old Boy: A Case Report Theresia Monica Rahardjo; Chandni P. Daryanani; Apriani Lam; Maxzillion Sky Kasnadi; Nadya Ariella; Stefanie Sumartono; Syifa Navisah
Medical Clinical Update Vol. 3 No. 1 (2023): June
Publisher : Rumah Sakit Unggul Karsa Medika

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Abstract

Henoch-Schonlein Purpura is the most common early life vasculitis in children. More than 90% arebelow ten years of age, with a median age of six years. This condition is a genetically autoinflam-matory disease. Immunoglobulin A plays an important role in the pathogenesis of his disease. It iscommonly self-restricting and harmless, but concomitant nephritis may occur as complication