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Uji Aktivitas Antikoagulan pada Sel Darah Manusia dari Ekstrak Bawang Bombai (Allium cepa L.) Fany Febriani; Junius Hardy; Riskianto
Pro-Life Vol. 10 No. 1 (2023): Maret
Publisher : Program Studi Pendidikan Biologi Fakultas Keguruan dan Ilmu Pendidikan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33541/pro-life.v10i1.4256

Abstract

Thromboembolic disorders can cause various life-threatening cardiovascular diseases. Anticoagulants are the most common treatment for thromboembolic disorders. Organosulfur compounds in onions, such as allicin and flavonoid compounds, have anticoagulant properties. The purpose of this study is to test the anticoagulant activity of onions extracted by maceration method using 96% ethanol as a solvent. The anticoagulant test was performed on samples of blood groups A, B, AB, and O using the Lee-White method. Six tubes were filled with 1 cc of each blood sample with treatments including control (without treatment), negative control (96% ethanol), positive control (EDTA), and variation of extract concentrations 5; 7.5; 10%. The results of 96% ethanol extract of Onion (Allium cepa Linnaeus) using the maceration method contains secondary metabolites including flavonoids, saponins, and phenols. The onion extract had a significant mean difference (p < 0.05) with the EDTA positive control group and did not produce a significant mean difference (p > 0.05) with the untreated group, so the onion extract with a concentration of 5; 7.5; 10% extracted with 96% ethanol solvent using maceration method had no anticoagulant activity. Blood type A, B, AB, and O did not have a significant difference in the mean blood clotting time with a value of P = 0.504 (p > 0.05).
Sosialisasi dan Pelatihan Pembuatan Simplisia, Ekstrak, dan Sediaan Jamu Serbuk Instan Kepada Guru dan Siswa Sekolah Menengah Kejuruan Farmasi Riskianto Riskianto; Jessica Novia; Fany Febriani; Yovita Diane Titiesari; Metta Tirta
CARADDE: Jurnal Pengabdian Kepada Masyarakat Vol. 6 No. 1 (2023): Agustus
Publisher : Ilin Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31960/caradde.v6i1.1962

Abstract

Sosialisasi dan pelatihan pembuatan simplisia, ekstrak, dan sediaan jamu serbuk instan kepada guru dan siswa SMK Farmasi di kabupaten Tangerang, Banten bertujuan untuk memberikan tambahan ilmu pengetahuan dan keterampilan dalam membuat sediaan obat tradisional yang memenuhi syarat mutu, khasiat, dan memiliki nilai jual. Metode pada kegiatan pengabdian kepada masyarakat ini yaitu melakukan pemberian materi melalui sosialisasi dan pelatihan pembuatan simplisia, ekstrak, dan sediaan jamu serbuk instan dengan baik. Pada awal dan akhir kegiatan dilakukan pretest dan posttest, serta survei kepuasan peserta untuk mengetahui keberhasilan dari kegiatan PkM ini. Hasil yang diperoleh dari pretest dan posttest yaitu 75,40 % dan 96,83%, diketahui terdapat peningkatan pengetahuan peserta sebesar 21,43% dari 75,40% menjadi 96,83% yang tergolong dalam kategori sangat baik. Total rerata nilai skor hasil survey kepuasan peserta yaitu 18,59 dengan rerata % nilai 92,95%, hasil ini menunjukkan respon dari peserta terhadap kegiatan PkM ini tergolong dalam kategori sangat baik. Kesimpulan dari PkM ini adalah terdapat peningkatan pengetahuan dari peserta terhadap pembuatan simplisia, ekstrak, dan sediaan jamu serbuk instan yang baik dan kepuasan peserta setalah Mengikuti kegiatan PkM tergolong dalam kategori sangat baik.
PENYULUHAN HIPERTENSI DAN DIABETES MELITUS PADA MASYARAKAT DESA CARINGIN, LEGOK, KABUPATEN TANGERANG Karnelasatri Karnelasatri; Andriyani Andriyani; Febbyasi Megawati; Yovita Diane Titiesari; Fany Febriani; Kevin Adithya Beda
Prosiding Konferensi Nasional Pengabdian Kepada Masyarakat dan Corporate Social Responsibility (PKM-CSR) Vol 8 (2025): Penguatan Ekonomi Masyarakat Berbasis Ekologis untuk Mencapai Keberlanjutan Menuju Ind
Publisher : Asosiasi Sinergi Pengabdi dan Pemberdaya Indonesia (ASPPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37695/pkmcsr.v8i0.2697

Abstract

Community Service activities in Caringin Village, Legok, were carried out through a series of activities including healthy exercises, health education, and free mini medical checkups. This program was conducted in collaboration with the Caringin Community Health Center, where educational materials on hypertension and diabetes mellitus (DM) were presented by doctors in the form of presentations, discussion, and health consultations. In addition, educational materials were also distributed via leaflets to reach residents who did not fully participate in the activities. The resident understanding was evaluated through pre- and post-tests, while activity implementation was evaluated through a satisfaction survey. The results of the free mini medical check-ups showed a high prevalence of hypertension, with 76% of residents having systolic blood pressure above 120 mmHg and 38% of them falling into the hypertension category of ≥140 mmHg. In addition, 17% of residents had blood sugar levels above normal, with 7% requiring further examination. The results of the evaluation of residents' understanding showed an average increase of 7%, while the satisfaction survey showed that the majority of residents were satisfied with the implementation of the activities (>90%). Some of the obstacles encountered were discrepancies in the number of participants who took the pretest and post-test, as well as misinterpretation of the pretest and post-test questions by residents, especially the elderly. However, this activity provided an overview of the effectiveness of an integrative approach to health education in raising awareness in the community and detecting early disease risks. Moreover, collaboration with local health service units provided opportunities for data-based follow-up on the results of the activity.