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Larasati Fauziah Yakub
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Pengaruh Nanostructured Lipid Carriers (NLC) Terhadap Sistem Penghantaran Obat Berlianna Nur Afiddah; Larasati Fauziah Yakub; Lisda Rahmawati; Janwar Janwar; Yudi Alfian; Nia Yuniarsih
Jurnal Ilmiah Wahana Pendidikan Vol 9 No 5 (2023): Jurnal Ilmiah Wahana Pendidikan
Publisher : Peneliti.net

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (47.166 KB) | DOI: 10.5281/zenodo.7726555

Abstract

NLC merupakan bagian dari platform nanoteknologi yang dapat dimanfaatkan untuk memodifikasi suatu sediaan dari farmakokinetik, bioavailabilitas dan sistem rilis suatu sediaan. Tujuan dengan adanya review ini untuk mengetahui pengaruh NLC terhadap sifat farmakokinetika, bioavailabilitas dan sistem rilis suatu sediaan topical, oral, parenteral dan ocula. Metode yang digunakan dalam penelitian kali ini berjenis review artikel dengan membandingkan sediaan yang menggunakan NLC serta sediaan yang tidak menggunkan NLC. Pengaruh NLC pada sediaan topical reservoir obat terbentuk di kulit dan konsentrasi obat yang tinggi dan nilai Cmax dalam sediaan tersebut meningkat juga mampu menghindari metabolism pada lintas pertama. Pada sediaan parenteral menunjukkan waktu paruh yang panjang (t1/2) dan nilai klirens (CL) yang rendah, pada sediaan oral meningkatkan bioavailabilitas meningkatkan AUC dan memperpanjang waktu kerja obat dan pada sediaan ocula meningkatkan bioavailabilitas dan mekanisme suatu obat dengan NLC 6,79 kali lipat dan 1,24 kali lipat pada area dibawah kurva konsentrasi waktu yaitu selama 12 jam dibandingkan obat yang tidak menggunakan NLC.
Review Artikel: Standar Pelayanan Kefarmasian di Puskesmas Indonesia Berlianna Nur Afiddah; Larasati Fauziah Yakub; Lisda Rahmawati; Janwar Janwar; Yudi Alfian; Indah Sari Amatun Nisa; Nia Yuniarsih
Jurnal Ilmiah Wahana Pendidikan Vol 9 No 5 (2023): Jurnal Ilmiah Wahana Pendidikan
Publisher : Peneliti.net

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (200.957 KB) | DOI: 10.5281/zenodo.7726581

Abstract

One of the efforts to improve health development in Indonesia is to improve health services at puskesmas, especially pharmaceutical services, because health services at puskesmas are inseparable from pharmaceutical services which include management of pharmaceutical preparations and consumable medical materials (BMHP), this aims to find out suitability of pharmaceutical services at puskesmas, especially in the management of drugs and clinical pharmacy services using the literature review method by tracing various sources through Google Scholar. Based on the results of tracing data from several journals at puskesmas in North Minahasa Regency, Tamohon City, Bolaang Regency, Klari Health Center, Karawang Regency, Cirebon City, Batu City, Magelang Regency and Tanjung Karang Health Center, it can be seen that these puskesmas have not yet destroyed pharmaceutical supplies and consumable medical materials. as well as counseling clinical pharmacy services, visits and monitoring of drug side effects. So it can be concluded that some of these puskesmas have not implemented pharmaceutical services in accordance with pharmaceutical service standards listed in Permenkes number 74 of 2016 concerning pharmaceutical service standards at puskesmas.
Pengaruh Pemberian Inotropik dan Vasoaktif dalam Menstabilkan Kadar MAP Pasien Syok Sepsis : Review Artikel Berlianna Nur Afiddah; Larasati Fauziah Yakub; Maya Arfania
Jurnal Ilmiah Wahana Pendidikan Vol 9 No 5 (2023): Jurnal Ilmiah Wahana Pendidikan
Publisher : Peneliti.net

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (101.501 KB) | DOI: 10.5281/zenodo.7728032

Abstract

In Indonesia, teachers' ability to undertake research is still below average. This is due to a lack of research knowledge and experience among teachers. As a result, teachers rarely conduct research and have never published a scientific paper. As a result, mentoring in the form of formal training in research competence is required. There is, however, no training structure designed expressly for instructors to improve their research competency. The goal of this study is to create a training system that will eventually improve instructors' research skills. The research and development process is based on a modified Dick & Carey development model. As a result, an upgraded teacher competency training system including training modules, training agendas, teaching books, and learning videos has been developed and tested by specialists. Teachers in Indonesia are expected to use the training system to increase their research skills.
Co-Authors Berlianna Nur Afiddah Indah Sari Amatun Nisa Janwar Janwar Lisda Rahmawati Maya Arfania Nia Yuniarsih Yudi Alfian