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POTENSI PEMBERIAN EKSTRAK MENIRAN (Phyllanthus Niruri L) TERHADAP PENINGKATAN RESPONS IMU HUMORAL PADA MENCIT YANG DI INFEKSI Salmonella enterica serovar Typhi Nisa, Arofatin
Jurnal Biosains Pascasarjana Vol 17, No 2 (2015): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (21.925 KB) | DOI: 10.20473/jbp.v17i2.2015.82-89

Abstract

Abstrak  Salah satu tanaman yang memiliki kandungan imunomodulator yaitu meniran (Phyllanthus niruri L). Beberapa golongan zat utama yang terkandung dalam meniran (Phyllanthus niruri L.) adalah lignan, tanin, polifenol, alkaloid, flavonoid, terpenoid dan steroid .Terhadap respon imun spesifik pemberian ekstrak meniran mampu meningkatkan proliferasi sel limfosit T, meningkatkan sekresi TNFα, IFNγ, dan IL-4 serta menurunkan sekresi IL-2 dan IL-10. Terhadap imunitas humoral, ekstrak meniran ini dapat meningkatkan produksi imunoglobulin M (IgM) serta imunoglobulin G (IgG) . Untuk mengetahui potensi ekstrak Phyllanthus niruri L dalam meningkatkan produksi IgM pada mencit yang diinfeksi Salmonella enterica serovar typhi  dilakukan penelitian dengan desain penelitian experimental. Pada penelitian ini  mencit dikelompokkan menjadi tiga kelompok  yaitu kelompok perlakuan yang diberikan ekstrak Phyllanthus niruri L secara per oral dengan dosis 0,2 ml dan diinfeksi Salmonella enterica serovar Typhi sebanyak 108, Kelompok kontrol positif yang diberikan larutan aquades dan diinfeksi Salmonella enterica serovar Typhi sebanyak 108. Kelompok kontrol negatif yang hanya diberikan larutan aquades. Peningkatan IgM spesifik dapat diamati dengan pemeriksaan ELISA dan  pemeriksaan WIDAL test. Data hasil ELISA dianalisis menggunakan uji ANOVA satu arah (p<0,005), dengan spps 17.0 for Windows.sedangkan data hasil WIDAL test dianalisis menggunakan Mann-whitney test ( p= 0,044), dengan spss 17.0 for windows. Hasil penelitian menunjukkan bahwa ekstrak meniran terbukti sebagai imunostimulator terhadap peningkatan  IgM spesifik. Kata-kata kunci: Salmonella enterica serovar Typhi, meniran (Phyllanthus niruri L ), IgM.
Study of The Needs of The World of Work Industry For Graduates of Health Vocational High Schools Nisa, Arofatin; Riyanto, Yatim; Soedjarwo, Soedjarwo
International Journal of Current Educational Research Vol. 4 No. 1 (2025): June
Publisher : Indonesia Emerging Literacy Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53621/ijocer.v4i1.423

Abstract

Objective: This study aims to describe the needs of the industry workforce for graduates of Health Vocational Schools. Method: This study employs a qualitative approach. Data collection is done through interviews, observations, and documentation studies. The object of this study is four industrial health facilities in the Surabaya area. The subjects of the study are health service business owners or personnel departments. Data analysis in qualitative research is carried out through four stages. Results: The challenging skill aspects required are the ability to operate a computer and good skills in each field of competence. Additional skills required are vital signs checks, monitoring child development, and basic childcare skills. The soft skills abilities required are teamwork, communication skills, leadership, networking, adaptability, friendliness, good work ethic, discipline, and empathy. Novelty: This study will examine the specific industrial needs of the workforce for graduates of Health Vocational High Schools, with a focus on the competency gap that still exists between the education curriculum and the demands of the healthcare industry. This study identifies the technical and non-technical skills most needed by companies in the health sector, thus providing new insights into improving the curriculum of Health Vocational High Schools.
Student Career Management Model at Vocational Health Education Level for the Work Industry Nisa, Arofatin; Riyanto, Yatim; Soedjarwo, Soedjarwo
International Journal of Current Educational Research Vol. 4 No. 1 (2025): June
Publisher : Indonesia Emerging Literacy Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53621/ijocer.v4i1.439

Abstract

Objective: This study aims to develop a career management model for students of Health vocational high schools in the workforce. Method: This study uses a descriptive method with a case study approach. The research objects are Nusantara Health Vocational High School and Surabaya Health Vocational High School. The research instruments are in-depth interview guides, observation guides, and documentation guides. The analysis uses multi-site analysis. Results: The results of the study found that the career management model for students of Health vocational high schools consists of 4 stages, namely 1) career management planning consisting of annual work meetings, involving the work industry in learning planning, and curriculum modification planning according to the needs of the work industry; 2) organizing career management consisting of dividing tasks and responsibilities based on areas of expertise, determining and confirming those responsible for each program, and determining coordination and integration paths between sections; 3) implementation of career management; and 4) career management supervision consisting of comprehensive supervision in all aspects, use of monitoring and evaluation instruments, involvement of alumni and the world of work in the monitoring and evaluation process. Novelty: This model uniquely incorporates active industry participation in curriculum design, field practice implementation, and alumni-involved evaluation while introducing a holistic structural coordination framework and integrated monitoring tools rarely applied in health vocational education contexts.