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All Journal Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Medika Malahayati
Paulus Taufik
General Practitioner, University of Mataram Hospital, West Nusa Tenggara
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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ROLE OF LOW-DOSE AZITHROMYCIN IN THE MANAGEMENT OF CYSTIC BRONCHIECTASIS: A CASE SERIES Paulus Taufik; Maulid Hidayat; Prima Bela Fathana
Jurnal Ilmu Kedokteran dan Kesehatan Vol 10, No 3 (2023): Volume 10 Nomor 3
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v10i3.9540

Abstract

Bronchiectasis is an abnormal chronic and persistent dilatation of the bronchi that is accompanied by destruction of the bronchial walls due to congenital or acquired disorders such as chronic respiratory tract infections. Recurrent respiratory tract infections are characteristic of bronchiectasis. Radiological examination plays a role in diagnosis, a thin section CT to confirm a diagnosis of bronchiectasis when clinically suspected, and provides clearer information on lung morphology. The goals of treating bronchiectasis are to prevent exacerbations, reduce complaints, improve the patient's quality of life, and stop the disease from worsening. Therapy is expected to address the proven underlying cause, cutting off the vicious cycle of bronchiectasis Long-term antibiotics are considered in patients with bronchiectasis with frequent exacerbations three or more times per year to relieve symptoms and reduce the frequency of exacerbations. Macrolides are a plausible alternative antibiotic and anti-inflammatory agent with a lower burden of treatment for bronchiectasis patients. We present three cases of Bronchiectasis that were admitted to Mataram University Hospital. The three cases were given Long-term antibiotics with low-dose Azithromycin for 2 and 3 months. This report demonstrates clinical improvement in a reduction of exacerbation frequency, improvement in quality of life, decreased sputum production, and increased ability to carry out activities in patients treated with low-dose azithromycin. The most common side effect that appears in three cases is gastrointestinal disturbances.
TUBERKULOSIS PARU DENGAN DIABETES MELLITUS TIPE 2 SETELAH MENYELESAIKAN TERAPI ANTI TUBERKULOSIS 9 BULAN: LAPORAN KASUS Paulus Taufik; Prima Belia Fathana
Jurnal Medika Malahayati Vol 7, No 2 (2023): Volume 7 Nomor 2
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jmm.v7i2.10427

Abstract

Abstrak : Tuberkulosis Paru Dengan Diabetes Mellitus Tipe 2 Setelah Menyelesaikan Terapi Anti Tuberkulosis 9 Bulan: Laporan Kasus. Tuberkulosis (TB) adalah penyakit menular yang disebabkan oleh bakteri Mycobacterium tuberculosis. Sebagian besar bakteri Mycobacterium tuberculosis menyerang paru-paru menyebabkan penyakit TB paru, tetapi dapat juga menyerang organ tubuh lainnya. Lima dari 8 negara dengan insiden TB tertinggi termasuk di antara 10 negara dengan prevalensi DM tertinggi. Individu yang rentan menghirup Mycobacterium tuberculosis melalui aerosol. Diabetes Mellitus ditemukan meningkatkan risiko tertular TB hingga tiga kali lipat, Diabetes Mellitus berdampak buruk pada hasil pengobatan TB karena efek imunosupresif dari DM itu sendiri, interaksi obat-obat, efek samping dari obat-obatan, kepatuhan pengobatan yang kurang optimal, berkurangnya bioavailabilitas obat-obatan dan faktor-faktor lain. Penatalaksanaan diabetes melitus (DM) selama pengobatan tuberkulosis (TB) ditujukan untuk meningkatkan hasil pengobatan TB dan menurunkan morbiditas dan mortalitas terkait DM. Laporan kasus ini menunjukan perbaikan klinis, kembalinya aktifitas fisik, meningkatnya berat badan dan meningkatnya kualitas hidup dari pasien yang menjalani pengobatan obat-anti tuberculosis pada pasien TB Paru dengan DM tipe 2 selama 9 bulan.
Co-Authors Maulid Hidayat Prima Bela Fathana Prima Belia Fathana