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All Journal Molecular and Cellular Biomedical Sciences (MCBS) World Nutrition Journal Journal Pharmacy of Tanjungpura
Rina Triana, Rina
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Dentistry Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Journal : World Nutrition Journal

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The role of MTHFR polymorphism on hyperhomocysteinemia and folic acid and vitamin B metabolism Triana, Rina
World Nutrition Journal Vol. 9 No. S1 (2025): Vol. 9 No. S1 (2025): Selected conference proceedings of the Nutri Symposium 2
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V09.S1.0010

Abstract

Non-communicable diseases (NCDs) remain a leading global health concern, with hyperhomocysteinemia recognized as a contributing metabolic disorder linked to cardiovascular disease, neurodegenerative conditions, and developmental anomalies. This presentation explores the pivotal role of methylenetetrahydrofolate reductase (MTHFR) polymorphisms—particularly C677T and A1298C variants—in disrupting homocysteine metabolism through impaired folate and vitamin B pathways.
Co-Authors Angliana Chouw, Angliana Nurrani Mustika Dewi, Nurrani Mustika Siska Darmayanti, Siska