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All Journal Jurnal Buana Farma
Ermi Abriyani
Fakultas Farmasi, Universitas Buana Perjuangan, Karawang, Jawa Barat, Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

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KANDUNGAN SENYAWA AKTIF PADA JAMBLANG (Syzygium Cumini (L) Skeels SEBAGAI ANTIDIABETES: LITERATURE REVIEW ARTICLE Himyatul Hidayah; Ermi Abriyani; Surya Amal; Reni Apria Ningsih
Jurnal Buana Farma Vol. 3 No. 1 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i1.776

Abstract

Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia caused by defects in insulin secretion, insulin action or both. It is said diabetes mellitus if blood sugar levels exceed 150 mg/dL, where the normal limit for blood sugar is 70-150 mg/dL. Treatment with natural ingredients has low side effects if used correctly. One of the plants that has anti-diabetic activity is jamblang or often called juwet (Syzygium cumini (L.). literature was conducted using Google Scholar, Science Direct, Researchgate and PubMed which were published in 2010-2020 with keywords related to the topic "Andiabetic activity syzygium cumini, jambolanun, Eugenia Jambolan antidiabetic and active compounds". The results of a review that has been carried out on the content of active compounds in jamun (Syzygium cumini (L) Skeels as an antidiabetic indicate that the active compounds in jamun are quercetin, quercetin-3-0-glycosides, rutin, mycaminose, chalcone and stigmasterol which have the potential to as an antidiabetic.
SKRINING FITOKIMIA DAN UJI ANTIOKSIDAN EKSTRAK DAUN KANGKUNG PAGAR (Ipomoea carnea Jacq) Ermi Abriyani; Lia Fikayuniar; Arie wichandar
Jurnal Buana Farma Vol. 3 No. 1 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i1.780

Abstract

The Kangkung pagar (Ipomea carnea Jacq) leaves the one source of antioxidant activity. This plant is used as traditional medicine and has potensially anti-oxidant, anti-microbial, immunostimulant, anti-cancer, liver protector and many pharmacological activities. Antioxidant can neutralize of free radicals by inhibiting the occurrence of oxidant. The aim of this study to determine of result of phytochemical screening, antioxidant activity by DPPH and FRAP methods. Methods of this study are phytochemicals screening, extraction of Ipomea carnea Jacq leave by maceration with ethanol 96%., antioxidant assays by DPPH and FRAP by determine EC50 value and the absorbances from spectroscopy UV Vis. . The result of phytochemicals screening are appear of alkaloids, flavonoids, terpenoids, steroids, saponins and tannins and antioxidants assays result EC50 value by FRAP methods were n-hexane (27.08 ppm, ethyl acetate 55.53 ppm, ethanol 68.23 ppm. While the results EC50 by DPPH methods were n-hexane 71.89 ppm, ethyl acetate 48.31 ppm and ethanol 41.07 ppm. It concluded that ipomea carnea Jacq. It can be concluded that the leaves of Ipomea carnea Jacq are a potensial source of antioxidants.
Co-Authors Arie wichandar Himyatul Hidayah Lia Fikayuniar Reni Apria Ningsih Surya Amal