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All Journal Jurnal Reka Lingkungan Indonesian Journal of Global Health research Narra J
Kunti Wijiarti, Kunti
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Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health

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Biomarkers for predicting COVID-19 mortality: A study at Sulianti Saroso Infectious Disease Hospital, Indonesia Maemun, Siti; Widiantari, Aninda D.; Murtiani, Farida; Herlina, Herlina; Tanjungsari, Dian W.; Wijiarti, Kunti; Pratiwi, Tiara Z.; Matondang, Faisal; Rusli, Adria; Rivaldiansyah, Rivaldiansyah; Tampubolon, Maria L.; Mariana, Nina; Setiawaty, Vivi; Purnama, Tri B.
Narra J Vol. 5 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i2.1936

Abstract

The high transmissibility and mortality rates of the COVID-19 pandemic pose significant challenges. Patients can deteriorate rapidly, making it crucial to identify laboratory biomarkers for high-risk individuals. The aim of this study was to evaluate the predictive value of various laboratory parameters, including C-reactive protein (CRP), D-dimer, ferritin, neutrophil-to-lymphocyte ratio (NLR), prothrombin time (PT), and procalcitonin (PCT), in predicting COVID-19 mortality. A retrospective cohort study was conducted at Sulianti Saroso Infectious Disease Hospital, where COVID-19 patients were categorized into survivors and non-survivors. The Mann-Whitney test was used to assess group differences, while receiver operating characteristic (ROC) curve analysis was performed to evaluate the predictive performance of each biomarker, with Youden's index (J) determining optimal cut-off values. Kaplan-Meier analysis was used to compare median survival times, and Cox regression assessed hazard rates and the relationship between biomarkers and mortality. A total of 1,598 patients were analyzed, the majority of whom were admitted with oxygen saturation levels >95% and classified as having mild to moderate disease severity. Among them, 216 patients died, resulting in a mortality rate of 13.52%. Significant variations in mortality rates were observed along the survival functions for NLR, ferritin, D-dimer, CRP, and PCT (p<0.001). The survival curves for these biomarkers demonstrated distinct trends across tertiles over time. Among hematological markers, NLR was significantly associated with mortality (p<0.001), with a 1.5–2.2% increased risk per unit increase. Biochemical markers (complete blood count) proved to be more effective than hematological parameters (NLR, ferritin, PT, D-dimer, CRP, PCT) when evaluating individual prognostic performance. Bivariate analysis of CRP, D-dimer, ferritin, NLR, PT, and PCT between survivors and non-survivors showed significant differences. Notably, NLR and PCT were highly relevant for predicting disease prognosis and mortality, with sensitivity and specificity values exceeding 80%.
Factors Related to the Implementation of Patient Safety Anitha, Anitha; Dwisusanti, Oktina; Nuraidah, Nuraidah; Wijiarti, Kunti; Pratiwi, Tiara Zakiyah; Maemun, Siti
Indonesian Journal of Global Health Research Vol 7 No 2 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i2.5293

Abstract

Patient safety is a critical global health issue. Despite solutions from JCI and WHO, 70% of medication errors still occur in many countries, including Indonesia. Objective: To identify factors influencing patient safety implementation by nurses at Sulianti Saroso Infectious Diseases Hospital (SSIDH). Methods: This cross-sectional observational study was conducted at SSIDH in October-November 2024. The population included 150 nurses, midwives, and heads of inpatient wards, selected using purposive sampling. Data were analysed using Kolmogorov-Smirnov, chi-square, and multiple logistic regression (p<0.05). Results: Most respondents were female and held a bachelor’s degree in nursing. Knowledge, attitude, and motivation were not significantly associated with patient safety implementation. Factors significantly influencing patient safety were age, duty room, and tenure (p<0.05). Nurses aged ≥40 years were four times less likely to implement patient safety standards compared to those <40 years (OR=4.04; 95%CI=1.68-9.72). Those working in non-intensive wards were 0.11 times less likely to implement standards (OR=0.11; 95%CI=0.05-0.27). Conclusion: Nurses/midwives should enhance patient safety implementation based on the six patient safety goals. Healthcare providers are encouraged to create programs to support quality improvement and reduce adverse events.
KUALITAS AIR LIMBAH RSPI SULIANTI SAROSO Tiardjiono, Mulya; Nurlaela, Nurlaela; Setyawati, Fajar Dwi; Nurhenifah, Eka Erlis; Anggraeni, Yeyen; Wijiarti, Kunti; Pratiwi, Tiara Zakiyah; Rivaldiansyah, Rivaldiansyah; Maemun, Siti
Jurnal Reka Lingkungan Vol 13, No 2 (2025)
Publisher : Institut Teknologi Nasional, Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26760/rekalingkungan.v13i2.177-192

Abstract

Rumah sakit memiliki peran penting dalam merawat pasien sakit. Namun  rumah sakit juga mempunyai kewajiban untuk memelihara lingkungan sekitar dari pencemaran limbah yang dihasilkan.  Penelitian ini merupakan studi kuantitatif yang bersifat deskriptif, bertujuan untuk menganalisis kualitas air limbah di RSPI Sulianti Saroso berdasarkan parameter pH, BOD, COD, zat padat tersuspensi (TSS), minyak dan lemak, amoniak, total koliform, zat organik (KmNO4), serta senyawa akibat biru metilen (MBAS) dari tahun 2022 sampai dengan 2024. Pengambilan sampel dilakukan di outlet Instalasi Pengolahan Air Limbah (IPAL) rumah sakit, dengan analisis yang dilakukan oleh Laboratorium Kesehatan Lingkungan Jakarta dan PT Unilab Perdana. Parameter yang diuji meliputi pH, Biochemical Oxygen Demand (BOD), Chemical Oxygen Demand (COD), Total Suspended Solids (TSS), minyak dan lemak, amonia, total koliform, zat organik (KmNO4), dan senyawa aktif biru metilen (MBAS). Penelitian ini menggunakan data sekunder dari Instalasi K3 dan Kesling. Pengolahan data dilakukan secara deskriptif dengan microsoft excel, ditampilkan dalam bentuk tabular, teks, atau gambar dengan analisis rerata, deviasi baku, median, frekuensi, dan persentase. Hasil penelitian ini menunjukkan bahwa semua parameter yang diuji berada dalam batas baku mutu yang ditetapkan. Sehingga pengelolaan air limbah berlangsung sesuai prosedur dan hasilnya efektif. Namun, pemantauan terus-menerus dan optimalisasi sistem pengolahan direkomendasikan untuk menjaga kepatuhan dan meningkatkan kualitas air limbah lebih lanjut.
Co-Authors Adria Rusli, Adria Anggraeni, Yeyen Anitha, Anitha Dwisusanti, Oktina Herlina Herlina Maemun, Siti Matondang, Faisal Murtiani, Farida Nina Mariana, Nina Nuraidah Nuraidah, Nuraidah Nurhenifah, Eka Erlis NURLAELA NURLAELA Pratiwi, Tiara Z. Pratiwi, Tiara Zakiyah Purnama, Tri B. Rivaldiansyah, Rivaldiansyah Setyawati, Fajar Dwi Tampubolon, Maria L. Tanjungsari, Dian W. Tiardjiono, Mulya Vivi Setiawaty Widiantari, Aninda D.