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All Journal Jurnal Widya Medika
Catharina Clarissa Ursia
Widya Mandala Catholic University
Medicine & Pharmacology

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THROUGH A MICROSCOPIC LENS: SKIN MICROBIOME AS THE CONFEDERATE IN ATOPIC DERMATITIS Catharina Clarissa Ursia; Patricia Dian Putri
JURNAL WIDYA MEDIKA Vol. 9 No. 1 (2023): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v9i1.4265

Abstract

Reciprocity between skin microbiome and the host underlies the occurrence, exacerbation, and severity of atopic dermatitis (AD). However, the role of skin microbiome in the pathogenesis of AD is yet to be depicted. This review highlights the host–microbiome interactions which relies on barrier status, microbiome composition, and microbe–microbe interactions. A microbiome shift, with abundance of S. aureus and lower microbial diversity, compromises the skin barrier function. It goes to show that epidermal barrier defect depletes the protective commensal skin bacteria and demonstrate how dysbiosis of the skin microbiome can lead to AD.
Co-Authors Putri, Patricia Dian