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Sinsanta Sinsanta
Departemen Patologi Klinik, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Kristen Krida Wacana, Jakarta, Indonesia.
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Pengaruh Pemberian Probiotik pada Infeksi Clostridium Difficile Ade Dharmawan; Dhimas Garin Dewa Agista; Sinsanta Sinsanta; Nicolas Layanto; Deby Deby
Jurnal MedScientiae Volume 1 No 2 : September - Desember 2022
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (641.716 KB) | DOI: 10.36452/jmedscientiae.v1i2.2567

Abstract

Clostridium difficile (C. difficile) is a gram-positive, anaerobic, spore-forming bacterium, and is an important pathogen in antibiotic-associated diarrhea. These bacteria are normal flora in the human digestive tract but can become pathogenic and form toxins consisting of 2, namely toxin A and toxin B. Due to antibiotics including risk factors for C. difficile infection (CDI), the treatment that can be given is probiotics. Probiotics may be effective in the prevention and treatment of CDI in several ways: alteration of gut flora, enhancement of antimicrobial activity, and as immunomodulators. The effect of probiotics, the method of administration, and the varying duration of administration make probiotics unable to be used as a therapy for C. difficile infection. However, probiotics can still be an option for adjuvant therapy in the treatment of CDI.
Pengaruh Pemberian Probiotik pada Infeksi Clostridium Difficile Ade Dharmawan; Dhimas Garin Dewa Agista; Sinsanta Sinsanta; Nicolas Layanto; Deby Deby
Jurnal MedScientiae Vol. 1 No. 2 (2022): Desember
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscie.v1i2.2567

Abstract

Clostridium difficile (C. difficile) is a gram-positive, anaerobic, spore-forming bacterium, and is an important pathogen in antibiotic-associated diarrhea. These bacteria are normal flora in the human digestive tract but can become pathogenic and form toxins consisting of 2, namely toxin A and toxin B. Due to antibiotics including risk factors for C. difficile infection (CDI), the treatment that can be given is probiotics. Probiotics may be effective in the prevention and treatment of CDI in several ways: alteration of gut flora, enhancement of antimicrobial activity, and as immunomodulators. The effect of probiotics, the method of administration, and the varying duration of administration make probiotics unable to be used as a therapy for C. difficile infection. However, probiotics can still be an option for adjuvant therapy in the treatment of CDI.
Overview of Routine Hematology Results in COVID-19 Patients at UKRIDA Hospital in 2021 Sinsanta Sinsanta; Inneke Kusumawati Susanto; Chandra Priawan
Jurnal MedScientiae Vol. 2 No. 1 (2023): April
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v2i1.2963

Abstract

Coronavirus Disease 2019, more commonly known as COVID-19, is an infectious disease that has a contagious nature, the etiologic cause is Severe Acute Respiratory Syndrome Coronavirus 2. Several clinical manifestations that commonly occur when infected with COVID-19 include acute respiratory system disorders, for example cough, fever and shortness of breath. on March 12 2020, WHO confirmed that COVID-19 was a pandemic case. This research was conducted in a cross-sectional descriptive manner, using consecutive sampling with a total sample of 110 patients, using secondary data in the form of medical records. It was concluded that the results of routine hematological examinations (hemoglobin, hematocrit, erythrocytes, leukocytes, platelets) were mostly normal, this was because the patients in the study sample were patients who had recently been infected with the Covid-19 virus, and the medical records taken were the results of a hematological examination. the first time when I entered the hospital. On examination of hemoglobin found 22 patients (20%) decreased. On leukocyte examination, it was found that 28 patients (25.5%) experienced a decrease in platelets, 15 patients (13.6%) decreased.
Co-Authors Ade Dharmawan Chandra Priawan Deby Deby Dhimas Garin Dewa Agista Inneke Kusumawati Susanto Nicolas Layanto