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All Journal Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Jurnal Farmasi Indonesia Jurnal Ilmu Kefarmasian Indonesia Journal of Pharmascience
Adji Prayitno Setiadi
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Informasi Obat pada Pasien Diabetes Mellitus Rawat Jalan di RSUD X Surabaya: Apa yang diberikan dan apa yang diketahui? Shieny Agustin Santoso; Adji Prayitno Setiadi; Karina Kumaladewi Widjaja; Yosi Irawati Wibowo
JURNAL ILMU KEFARMASIAN INDONESIA Vol 21 No 1 (2023): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v21i1.1104

Abstract

The prevalence of Diabetes Mellitus (DM) in Indonesia has increased 0.5% in the last five years. This study aimed to evaluate information provided and level of knowledge among DM patients on their treatment at the outpatient clinic at the X Public Hospital (Rumah Sakit Umum Daerah, RSUD), Surabaya, Indonesia. This was a cross-sectional study using a checklist developed by The Food And Drug Supervisory Agency which consists of 11 types of information. The data were analysed descriptively; to test the relationship between the amount of information provided and the patient's level of knowledge, Spearman correlation analysis was used. A total of 110 patients were included in this study (response rate 90.91%). The mean of information provided and understood by patients was 6.48/11±0.73 and 7.48/11±0.90, respectively. There was a significant relationship between information provided to and known by patients (p=0.001). Characteristic factors such as age (p=0.001), education level (p=0.001), and sources of information related to DM (p=0.014) were shown to influence DM patients' knowledge of their treatment. This study indicated the importance of providing clear and complete drug information, especially for patients on long-term therapy, to improve their knowledge, thus potentially increasing adherence and optimizing therapy outcomes.
a Kajian Naratif Pengukuran Kualitas Peresepan Pasien Diabetes Mellitus Lanjut Usia Fisia Niti Admadja; Yosi Irawati Wibowo; Karina Kumaladewi Widjaja; Adji Prayitno Setiadi
Jurnal Farmasi Indonesia Vol 20 No 1 (2023): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v20i1.1468

Abstract

The aging populations has increased worldwide, resulting in higher prevalences of non-communicable diseases, including Diabetes Mellitus (DM). Elderly with DM requires long-term prescribing which warrants special considerations. Hence, this narrative review aims to identify quality measurement tools and quality prescribing in elderly patients with DM. This review included literature searching in three databases [i.e., Pubmed (MEDLINE), Science Direct, and CINAHL] with combination of keywords: (Diabetes) AND (Elderly OR older OR geriatric) AND (“Potentially inappropriate medication” OR “potentially inappropriate prescribing” OR “inappropriate prescribing” OR “quality prescription” OR “rational prescribing”). The searching resulted in 1059 articles; and after the selection process, 10 articles were included in this study. The extracted data indicated that tools with explicit criteria (such as Beer's Criteria) were more commonly used to measure quality prescribing in elderly patients with DM compared to those with implicit criteria (i.e., Prescribing Quality Assessment Checklist) (9 articles versus 1 article, respectively). Varying quality prescribing were reported dependent on the tools used. The percentage of Potentially Inappropriate Medication (PIM) measured using explicit tools ranged from 22,7% to 68,1%; glibenclamide or glyburide were among the most common PIM. Whereas, 83.2% of precriptions measured with the implicit criteria in one article indicated poor quality. This finding demonstrated the needs of strategy to improve the quality of prescribing in elderly patients with DM.
Studi Efektivitas Ketorolak Versus Metamizol Untuk Nyeri Paska Operasi Transurethral Resection Of The Prostate (TURP) Ita Octafia; Riza Mazidu Sholihin; Yosi Irawati Wibowo; Adji Prayitno Setiadi
Jurnal Ilmu Farmasi dan Farmasi Klinik No 1 (2024): JIFFK Special Edition Suppl. 2
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/jiffk.v2i1.9197

Abstract

Limited evidence was available on the use of analgesic post-transurethral resection among patients with Benign Prostate Hyperplasia (BPH). This research was conducted at dr. Harjono Ponorogo Regional Public Hospital in September – November 2021. A total of 90 patients with BPH was randomly assigned to receive Ketorolac injection 30 mg (n=45) and Metamizole 1000 mg injection (n=45) post-TURP. Numeric Rating Scale (NRS) was used to measure the level of pain before surgery (T0); and 30 minutes (T1), 1 hour (T2), 2 hours (T3), 4 (T4) and 6 hours (T5) after surgery. In addition, haemoglobin (Hb) values and adverse events were observed. Inferential statistical tests were used to analyze differences between the two groups. The level of pain in the Metamizole group was lower than Ketorolac group at T1 and T2 (2.71 versus 2.18, p=0.001; and 2.51 versus 2.11, p=0.000; respectively). The AUC values between the two groups showed a statistical difference (p=0.02). The Hb values pre- and post-TURP were significantly different in Metamizole as well as Ketorolac groups (all p=0.001), but there was no difference between groups. This finding indicates that Metamizole injection can be considered as an alternative  for post-TURP analgesic with better availability and lower cost
Analysing Factors Contributing to Length of Stay (LoS) Among Patients with COVID-19 in Indonesian Hospital Setting Sonny Edbert; Yosi Irawati Wibowo; Adji Prayitno Setiadi
Journal of Pharmascience Vol. 12 No. 2 (2025): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v12i2.22557

Abstract

Penyakit COVID-19 masih menjadi ancaman konstan bagi kesehatan masyarakat global. Penggunaan obat dan lama rawat inap (LoS) merupakan indikator utama kualitas pelayanan di rumah sakit. Penelitian ini bertujuan untuk mengamati LoS dan faktor yang mempengaruhinya (termasuk karakteristik pasien dan penggunaan obat) pada pasien rawat inap COVID-19 di Rumah Sakit X di Surabaya, Indonesia. Penelitian observasional dilakukan dengan menggunakan rekam medis pasien rawat inap COVID-19 di Rumah Sakit X selama tahun 2022. Data karakteristik pasien dan profil obat dianalisis secara deskriptif. Kesesuaian terapi obat ditentukan berdasarkan pedoman terapi. Uji korelasi dilakukan untuk hubungannya dengan LoS. Total terdapat 203 pasien rawat inap COVID-19, meliputi: neonatus/anak/remaja (12,32%), dewasa (66,5%), dan lanjut usia (21,2%). Sebagian besar pasien laki-laki (54,2%) dengan keparahan sedang (80,8%), dan 36,4% memiliki komorbiditas. Kesesuaian terapi pada pasien neonatus/anak/remaja, dewasa, dan lanjut usia adalah: 12% (3/25), 76% (103/135), 60% (26/43), secara berurutan. Rata-rata LoS adalah 7,0±3,11 hari, dimana LoS terendah pada neonatus/anak/remaja (6,1±2,43 hari) dan tertinggi pada lansia (7,4±3,02 hari). Faktor yang secara signifikan mempengaruhi LoS adalah status vaksinasi (p= 0,000) dan tingkat keparahan COVID-19 (p= 0,002), namun tidak dipengaruhi oleh kesesuaian terapi (p= 0,864). Hasil penelitian merupakan data awal tuntuk mengembangkan strategi perbaikan kualitas layanan untuk pasien COVID-19 rawat inap. Kata Kunci: COVID-19, Faktor Risiko, Penggunaan Obat, Lama Rawat Inap, Rumah Sakit  ABSTRACT COVID-19 disease remains a constant threat to global public health. Drug use and Length of Stay (LoS) are among main indicators of service quality in hospitals. Object of this research were understanding of LoS and the contributing factors (including patient characteristics and drug use) among COVID-19 inpatients at Hospital X Surabaya, Indonesia. Observational research was conducted using medical records of COVID-19 inpatients at Hospital X in 2022. Data on patient characteristics and drug profiles were analyzed descriptively. Drug therapy conformity was determined based on guidelines. Correlation tests were used to determine factors associated to LoS. The results were 203 COVID-19 inpatients, including: neonate/child/adolescent (12.32%), adults (66.5%) and elderly (21.2% ). Most patients were males (54.2%) with moderate severity (80.8%), and 36.4% had comorbidities. Therapy conformity in neonate/child/adolescent, adult and elderly patients were: 12% (3/25), 76% (103/135), 60% (26/43), respectively. The average LOS was 7.0±3.1 days, where neonate/child/adolescent was the lowest (6.1±2.43 days), and elderly was the highest (7.4 ± 3.02 days). Significant contributing factors to LoS included vaccination status (p= 0.000) and COVID-19 severity (p= 0.002), but not with therapy conformity (p=0.864). The study findings provide a preliminary data to guide the development of strategies to improve service quality for hospitalised patients with COVID-19.
Co-Authors Fisia Niti Admadja Ita Octafia Karina Kumaladewi Widjaja Riza Mazidu Sholihin Shieny Agustin Santoso Sonny Edbert Wibowo, Yosi Irawati