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All Journal Indonesian Journal of Urology Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) ASEAN Journal of Chemical Engineering Jurnal Sosial dan Teknologi Ahmar Metastasis Health Journal (AMHJ) Jambura Medical and Health Science Journal
Riza Mazidu Sholihin
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Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Dentistry Engineering Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health

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ESWL EFFECTIVENESS FOR LOWER POLE KIDNEY STONES Sholihin, Riza Mazidu; Soetojo, Soetojo; Muris, Haviv
Indonesian Journal of Urology Vol 26 No 1 (2019)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v26i1.443

Abstract

Objective: To describe the profile of lower pole kidney stone patients who underwent Extracorporeal Shock Wave Lithotripsy (ESWL) and the clearance rate of ESWL for lower pole kidney stones at Soetomo General Hospital from 2012 to 2016. Material & Methods: This research design was analytical retrospective, lower pole kidney stone patients who underwent ESWL in Soetomo General Hospital from 2012 to 2016 who fulfill inclusion criteria become samples in this research. Samples were divided into two group, stone size <15 mm and 15-20 mm. Results: Total samples in this study were 128, consist of 81 males and 47 females. The age average was 48 ± 11.124. The stone size average was 9.5 ± 4.5 mm consisted of 109 patients with stone size <15 mm and 19 patients with stone size 15-20 mm. There were 119 single lower pole kidney stones and 9 multiple ones. From all patients, 77 patients (60.2%) were stones free and the rest (39.8%) were not. Stone free rate for lower pole kidney stones was higher in stone size <15 mm compared with 15-20 mm, 65.2% and 31.5% respectively. Statistical analysis with Chi-square showed significant ESWL clearance rate difference between lower pole kidney stone size <15mm group and 15-20 mm (p<0.05). Conclusion: ESWL was a safe option for lower pole kidney stones with high success rate. There was significant relationship between stone size and stone clearance rate. ESWL was effective for lower pole kidney stones size <15 mm. 
THE EFFECTIVITY OF EUTECTIC MIXTURE OF LOCAL ANESTHETICS CREAM AS EXTRACORPOREAL SHOCKWAVE LITHOTRIPSY ADJUVANT ANALGESIA IN SOETOMO GENERAL HOSPITAL Sholihin, Riza Mazidu; Hakim, Lukman; M. Soebadi, Doddy
Indonesian Journal of Urology Vol 26 No 2 (2019)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v26i2.509

Abstract

Objective: The Extracorporeal Shockwave Lithotripsy (ESWL) procedure is the first choice for kidney stone therapy with the size ≤20mm. One of the complications of ESWL is the pain. Pain control during ESWL is essential to maintain the focus point of ESWL and give enough time to achieve complete stone fragmentation. Until now there is still no data about the effectiveness of Eutectic Mixture of Local Anesthetics (EMLA) cream as an adjuvant analgesic for ESWL procedure in Soetomo Hospital Surabaya. To compare the onset of pain and ESWL Wong-Baker Pain Scale (WBPS) between the EMLA group and placebo group. Material & Methods: The design of this study was a single-blind randomized control trial comparing the onset of pain and Wong Baker pain scale between the patient in EMLA group and placebo one. WBPS is assessed in minute 15, 30, 45, and 60 of ESWL sessions and 60 minutes post ESWL procedure. The results were analyzed with SPSS. Pain onset and differences of WBPS were tested by using independent T-test if the data is normally distributed and using Mann-Whitney test if the data is not normally distributed. Results: 10 patients were obtained in each group. The mean onset of pain in the EMLA group was longer than the mean onset of pain in the placebo group but statistically not significant (p>0.05). The WBPS in the EMLA group was significantly lower compared with the placebo group in the 30, 45, and 60 minutes of ESWL (p<0.05). Conclusion: EMLA cream application before ESWL was effective and safe as an adjuvant analgesic to reduce pain during ESWL.
Extractive Distillation of Ethanol/Water with 1-Butyl-3-Methylimidazolium Bromide Ionic Liquid as a Separating Agent: Process Simulation Hartanto, Dhoni; Handayani, Prima Astuti; Astuti, Widi; Kusumaningtyas, Ratna Dewi; Purwana, Yulian Candra; Maftukhaturrizqiyah, Maftukhaturrizqiyah; Wijayanti, Reni Titis; Wulansari, Durroti Zuhriah; Wulansarie, Ria; Pradnya, Irene Nindita; Hadikawuryan, Danang Subarkah; Wibowo, Agung Ari; Sholihin, Riza Mazidu; Chafidz, Achmad; Khoiroh, Ianatul
ASEAN Journal of Chemical Engineering Vol 23, No 3 (2023)
Publisher : Department of Chemical Engineering, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ajche.72250

Abstract

Ethanol purification has become of great interest recently because ethanol can be used as renewable energy, solvent in many industries, and for medicinal purposes. The separation of ethanol from water is challenging because the azeotropic point has appeared in this binary mixture. Extractive distillation technology is one of the most interesting methods to separate ethanol from water due to the competitiveness of its energy consumption and capital investment costs. Ionic liquids such as 1-butyl-3-methylimidazolium bromide [BMIM] [Br], categorized as a green solvent, produce a significant salting-out effect in the ethanol-water system. This makes ionic liquid a promising solvent in ethanol-water separation. This study simulated the extractive distillation of an ethanol-water system with 1-butyl-3-methylimidazolium bromide as a solvent. The simulation and sensitivity analysis were performed on the Aspen Plus Process Simulator to obtain the optimum configuration. The NRTL thermodynamic model was used in this study. The effects of the number of stages (NS), binary feed stage (BFS), entrainer feed stage (EFS), and reflux ratio (RR) on the ethanol concentration with minimum energy requirements were studied. The most optimal configurations to produce a high ethanol concentration with less energy are NS 28, BFS 22, EFS 4, and RR 1.5.
Delayed Management of Pediatric Testicular Torsion with Absence of Severe Pain : An Evidance-Based Case Report Kartika, Pramudita Angga; Sholihin, Riza Mazidu
Jambura Medical and Health Science Journal Vol 2, No 2 (2023): Jambura Medical and Health Science Journal
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/jmhsj.v2i2.21818

Abstract

Testicular torsion is a surgical emergency. To protect the affected gonad, early diagnosis and surgical therapy are essential. The pediatrician's difficulty in communicating his complaints is one of the potential patient-specific causes for a delayed diagnosis related to any of these symptoms. We describe a case of unilateral testicular torsion in a 13-year-old child who had complained of swelling but hadn't experienced intense scrotal discomfort in six days. His right testicle was completely shattered. When the right testicle was discovered to have a 360-degree torsion and to be detorted but not viable in the operating room, it had an orchidectomy, and the left testis underwent an orchidopexy. Three internet databases—PubMed, Google Scholar, and Science Direct—were used to search the literature. An English journal that discusses pediatric testicular torsion has inclusion criteria. There is insufficient research on testicular torsion that manifests with painless symptoms. Treatment could be postponed if this phenomenon isn't considered appropriately.Keywords : Delayed management, painless, pediatrics, testicular torsion
Studi Efektivitas Ketorolak Versus Metamizol Untuk Nyeri Paska Operasi Transurethral Resection Of The Prostate (TURP) Ita Octafia; Riza Mazidu Sholihin; Yosi Irawati Wibowo; Adji Prayitno Setiadi
Jurnal Ilmu Farmasi dan Farmasi Klinik No 1 (2024): JIFFK Special Edition Suppl. 2
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/jiffk.v2i1.9197

Abstract

Limited evidence was available on the use of analgesic post-transurethral resection among patients with Benign Prostate Hyperplasia (BPH). This research was conducted at dr. Harjono Ponorogo Regional Public Hospital in September – November 2021. A total of 90 patients with BPH was randomly assigned to receive Ketorolac injection 30 mg (n=45) and Metamizole 1000 mg injection (n=45) post-TURP. Numeric Rating Scale (NRS) was used to measure the level of pain before surgery (T0); and 30 minutes (T1), 1 hour (T2), 2 hours (T3), 4 (T4) and 6 hours (T5) after surgery. In addition, haemoglobin (Hb) values and adverse events were observed. Inferential statistical tests were used to analyze differences between the two groups. The level of pain in the Metamizole group was lower than Ketorolac group at T1 and T2 (2.71 versus 2.18, p=0.001; and 2.51 versus 2.11, p=0.000; respectively). The AUC values between the two groups showed a statistical difference (p=0.02). The Hb values pre- and post-TURP were significantly different in Metamizole as well as Ketorolac groups (all p=0.001), but there was no difference between groups. This finding indicates that Metamizole injection can be considered as an alternative  for post-TURP analgesic with better availability and lower cost
Analisis Waktu Kunjungan Pasien Kronis di Depo Farmasi Rawat Jalan RSUD dr. Hardjono S. Ponorogo dalam Sistem Layanan BPJS Kesehatan Octafia, Ita; Hardiana, Luvia; Andari, Susilowati; Sholihin, Riza Mazidu; Aini, Iffah Qurratu
Jurnal Sosial Teknologi Vol. 6 No. 1 (2026): Jurnal Sosial dan Teknologi
Publisher : CV. Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jurnalsostech.v6i1.32650

Abstract

Chronic diseases are a major cause of morbidity and mortality in Indonesia. To ensure patients receive optimal therapy, BPJS Kesehatan (Indonesian Health Insurance) has established a regular patient visit schedule through the Referral Back Program (PRB). However, discrepancies often occur between patient visit times. To control medication administration, Dr. Harjono S Ponorogo Regional General Hospital (RSUD) formed a verification team. The purpose of this study was to analyze the visit times of chronic patients at the outpatient pharmacy depot of Dr. Harjono S Ponorogo Regional General Hospital within the BPJS Kesehatan service system. This study used a cross-sectional design. The research instrument was an observation sheet to record the number of prescriptions for chronic patients that were inconsistencies with the visit schedule from October to December 2024. Data analysis is the calculation of the number of chronic prescriptions against the visit schedule. Based on research at RSUD dr. Hardjono S. Ponorogo in October 2024 there was a rejection of 1.13%, in November 2024 there was a rejection of 0.93% and in December 2024 there was a rejection of 1.28%. Influencing factors are patient condition, compliance with treatment and external factors. Based on the results of research on the Analysis of Chronic Patient Visit Time at the Outpatient Pharmacy Depot RSUD dr. Harjono S. Ponorogo in the BPJS Health Service System, rejections still occur in the BPJS Health application system.
Safety and Efficacy Triple Drug Therapy (IDA) versus Two-drug therapy DA in Lymphatic Filariasis: A Systematic Review octafia, Ita; Sholihin, Riza Mazidu
Ahmar Metastasis Health Journal Vol. 5 No. 3 (2025): Ahmar Metastasis Health Journal
Publisher : Yayasan Ahmad Mansyur Nasirah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/amhj.v5i3.602

Abstract

Lymphatic filariasis (elephantiasis) is a parasitic disease caused by Wuchereria bancrofti, Brugia malayi, and Brugia timori, and is transmitted through the bite of infected mosquitoes. This disease is classified as a neglected tropical disease and has been targeted for global elimination through mass drug administration strategies. This systematic review aimed to evaluate the safety and effectiveness of a single-dose triple-drug therapy consisting of ivermectin, diethylcarbamazine, and albendazole (IDA) compared with the two-drug regimen of diethylcarbamazine and albendazole (DA) based on randomized clinical trials. A literature search was conducted in PubMed using the keyword “elephantiasis,” yielding eleven relevant studies published within the last five years. The results indicated that moderate adverse events occurred more frequently with IDA therapy, although most were mild in nature, while serious adverse events were more commonly reported with DA therapy. No significant differences were observed in filarial antigen levels between the groups. IDA therapy was well tolerated and considered as safe as DA, while demonstrating greater effectiveness in clearing microfilariae. With high coverage of mass drug administration, widespread use of IDA has the potential to accelerate the elimination of lymphatic filariasis.
Co-Authors Adji Prayitno Setiadi Agung Ari Wibowo Aini, Iffah Qurratu Chafidz, Achmad Dhoni Hartanto Hadikawuryan, Danang Subarkah Hardiana, Luvia Ita Octafia Kartika, Pramudita Angga Khoiroh, Ianatul Lukman Hakim M. Soebadi, Doddy Maftukhaturrizqiyah, Maftukhaturrizqiyah Muris, Haviv Octafia, Ita Pradnya, Irene Nindita Prima Astuti Handayani Purwana, Yulian Candra Ratna Dewi Kusumaningtyas Ria Wulansarie, Ria Soetojo Soetojo Susilowati Andari Wibowo, Yosi Irawati Widi Astuti Wijayanti, Reni Titis Wulansari, Durroti Zuhriah