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All Journal Indonesian Journal of Chemistry Biosaintifika: Journal of Biology & Biology Education
Venny Santosa
Universitas Kristen Satya Wacana, Graduate Program Of Biology
Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Chemistry

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PHOTODYNAMIC THERAPY: NEW LIGHT IN MEDICINE WORLD Venny Santosa; Leenawaty Limantara
Indonesian Journal of Chemistry Vol 8, No 2 (2008)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (210.004 KB) | DOI: 10.22146/ijc.21638

Abstract

Photodynamic therapy (PDT) is a considerably new kind of photochemotherapeutic treatment in medical field. It combines the use of three components, which are a photosensitizer, light and oxygen. Photosensitizer is a compound activated by light. The application can be oral, topical or intravenous. It usually member of porphyrin group with ampiphilic characteristics. Photosensitizer can be of generation I, II or III, each generation step develops more specificity, selectivity and deeper tissue application. This review will discuss photosensitizer development consecutively, with its benefit and lackness. The light used is usually on red region, while the oxygen is involved in reactive oxygen species generation. Its mechanism action can go through either in type I or type II reaction. This kind of therapy is usually being used in oncology, especially in superficial and in-lining cancers, dermatology and ophthalmology field. This therapy can be safely given to patients with complication and has distinct advantages compare with other treatment such as chemotherapy and surgery. It also considerably has lesser side effects and risks. Broader application is being developed through various experiments and photosensitizer modification.
Retracted: Characterization of the Interaction between RIN13 (RPM1-Interacting13) and Sumo Proteins in Arabidopsis thaliana. This article has been retracted at the request of the author. The reason is due to poor quality of the publication, which may reflect poorly on the scientific quality of the authors. Venny Santosa; Mio Nagabuchi; Sachiko Okada; Katsunori Tanaka
Biosaintifika: Journal of Biology & Biology Education Vol 9, No 2 (2017): August 2017
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v9i2.9487

Abstract

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Co-Authors Katsunori Tanaka Leenawaty Limantara Mio Nagabuchi Sachiko Okada