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All Journal Nusantara Scientific Medical Research Journal
Muhammad Fauzan Lubis
Department of Pharmaceutical Biology, Faculty of Pharmacy Universitas Sumatera Utara
Dentistry Health Professions Medicine & Pharmacology Nursing Veterinary

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Antibacterial Activity Ethanolic Extract of Ocimum basilicum L. Leaves in Inhibiting the Growth of Escherichia coli and Pseudomonas aeruginosa Muhammad Fauzan Lubis; Hafid Syahputra; Ririn Astyka
NSMRJ: Nusantara Scientific Medical Research Journal Vol. 1 No. 1 (2022): NSMRJ: Nusantara Scientific Medical Research Journal
Publisher : Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (454.792 KB) | DOI: 10.58549/nsmrj.v1i1.15

Abstract

Infectious disease is the biggest problem in the world. The problem with this infection is related to antibiotic resistance if its use is not consistent. Utilization of kemangi leaves, which are always used as fresh vegetables, has potential as an antibacterial in inhibiting the growth of Escherichia coli and Pseudomonas aeruginosa bacteria. This study aims to analyze the inhibition of an ethanol extract of kemangi leaves against Escherichia coli and Pseudomonas aeruginosa. The Kirby-Bauer method with the disc diffusion method was used to determine the minimum inhibitory diameter and to calculate the activity index value. The test results at a concentration of 500 mg/mL showed activity in the strong category, namely 13.70 ± 0.10 mm (Escherichia coli) and 12.93 ± 0.06 mm (Pseudomonas aeruginosa), and the minimum inhibitory concentration was at a concentration of 3.125 mg/mL. Conclusion the ethanol extract of kemangi leaves shows antibacterial activity.
Co-Authors Hafid Syahputra Ririn Astyka