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Socialization and Education on The Benefits of Probiotics for Children's Health in Primary School Until Senior High School Students in Tanjung Morawa Henni Cintya; Lisda Rimayani; Hafid Syahputra
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 6 No. 2 (2021): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (384.263 KB) | DOI: 10.32734/abdimastalenta.v6i2.5024

Abstract

Dysbiosis is a condition in which there is an imbalance in the number of microorganisms in the human digestive tract. This condition often occurs in children. An imbalance in the number of microorganisms in the digestive tract in humans (microflora) occurs when bacterial overgrowth. This can cause infection or inflammation localized in the intestine which has the potential to cause various diseases. However, knowledge about probiotics is still not understood by the public. This community service activity aims to provide knowledge about the role of probiotic microorganisms for children's health, especially for elementary-high school children in Tanjung Morawa District. This Community Service activity was carried out by means of a lecture method by disseminating the activity plan to the children of the Yayasan Pauly Mandiri, then a demonstration by conducting counseling and displaying animated videos related to the socialization that was carried out. Community service activities in general received a very good response and high enthusiasm from students, and several teachers who attended as well as the chairman of the Pauly Mandiri Education Foundation in Kec. Tanjung Morawa asked to continue. The results of community service, especially practicing drinking probiotic drinks. The enthusiasm of the participants hopes that this outreach activity can be resumed regarding the manufacture of food or drinks containing probiotics so that children can apply them daily, and consume them to increase body immunity in the midst of a pandemic.
Pelayanan Informasi dan Konseling oleh Apoteker tentang Penyakit Degeneratif serta Pemeriksaan Kesehatan kepada Masyarakat di Desa Ndokum Siroga: Information and Counseling Services by an Apothecary about Degenerative Diseases and Health Checks to the Community in Ndokum Siroga Village Hafid Syahputra; Aminah Dalimunthe; Nazliniwaty Nazliniwaty; Lisda Rimayani Nasution
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 7 No. 4 (2022): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v7i4.3040

Abstract

Degenerative disease is a disease experienced by many people, such as hypertension, coronary heart disease, diabetes mellitus, gout, and others. Pharmacists play a role in providing information and education about health, primarily pharmacological and non-pharmacological drugs. The purpose of the activity is to increase public understanding regarding degenerative diseases from the side of treatment by pharmacists by adopting a healthy lifestyle and understanding the importance of health checks as the first step to early detection of degenerative diseases. The implementation method is in the form of health checks in the form of blood pressure, cholesterol, uric acid, and blood sugar levels so that it can be early detection of degenerative diseases. Information and counseling services by pharmacists regarding healthy lifestyles and information related to treatment and degenerative diseases using brochures and individual direct delivery. The activity was carried out in Ndokum Siroga Village, Karo Regency. The service results were carried out at the village hall with 35 participants. The activity was full of enthusiasm, and many questions arose during the service by the pharmacist. It is known that participants' understanding of degenerative diseases is very low, with only 24% who know about degenerative diseases, 32% who know the symptoms of the disease, 27% who know the risks, and 30% who apply preventive and promotive efforts. 14% of participants do not know that they have the degenerative disease, so it can be concluded that this activity is very helpful and provides good benefits to the community.
Characterization, Phytochemical Screening of Phyllanthus emblica L. Fruit Nanoherbal and Determination of the Estrus Cycle of Female Rats Nurul Suci; Masfria; Aminah Dalimunthe; Hafid Syahputra
International Journal of Science, Technology & Management Vol. 4 No. 1 (2023): January 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i1.727

Abstract

One of a plant that is thought to have quite high antioxidant activity is kemloko (Phyllanthus emblica L.). This plant is a material that is often used by the community as a traditional medicine. This plant in India has been used to treat cancer, diabetes, liver (liver), heart problems and anemia. This biological activity is thought to be caused by the presence of bioactive compounds from secondary metabolites contained therein, especially compounds from the phenolic and flavonoid groups. The short length of the estrus cycle of rats makes them ideal for investigation of changes occurring during the reproductive cycle. The estrus cycle lasts four days and is characterized as: proestrus, estrus, metestrus and diestrus, which may be determined according to the cell types observed in the vaginal smear. Since the collection of vaginal secretion and the use of stained material generally takes some time, the aim of the present work was to provide researchers with some helpful considerations about the determination of the rat estrus cycle phases in a fast and practical way. This study began with macroscopic examination, examination of water content, examination of water-soluble extract levels, examination of ethanol-soluble extracts, examination of total ash content, and also an examination of acid-insoluble ash levels, phytochemical screening of Phyllanthus emblica L. fruit nanoherbal and determination of the estrus cycle of female rats. The results of phytochemical screening showed that the compound of Phyllanthus emblica L. Fruit nanoherbal contained a class of secondary metabolites of alkaloids, flavonoids, tannins, saponins, steroids/triterpenoids, and glycosides. And the estrus cycle of female rats can be determined by observing changes in vaginal epithelial cells.
Antibacterial Activity Ethanolic Extract of Ocimum basilicum L. Leaves in Inhibiting the Growth of Escherichia coli and Pseudomonas aeruginosa Muhammad Fauzan Lubis; Hafid Syahputra; Ririn Astyka
NSMRJ: Nusantara Scientific Medical Research Journal Vol. 1 No. 1 (2022): NSMRJ: Nusantara Scientific Medical Research Journal
Publisher : Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (454.792 KB) | DOI: 10.58549/nsmrj.v1i1.15

Abstract

Infectious disease is the biggest problem in the world. The problem with this infection is related to antibiotic resistance if its use is not consistent. Utilization of kemangi leaves, which are always used as fresh vegetables, has potential as an antibacterial in inhibiting the growth of Escherichia coli and Pseudomonas aeruginosa bacteria. This study aims to analyze the inhibition of an ethanol extract of kemangi leaves against Escherichia coli and Pseudomonas aeruginosa. The Kirby-Bauer method with the disc diffusion method was used to determine the minimum inhibitory diameter and to calculate the activity index value. The test results at a concentration of 500 mg/mL showed activity in the strong category, namely 13.70 ± 0.10 mm (Escherichia coli) and 12.93 ± 0.06 mm (Pseudomonas aeruginosa), and the minimum inhibitory concentration was at a concentration of 3.125 mg/mL. Conclusion the ethanol extract of kemangi leaves shows antibacterial activity.
Training on the Use of Processed Herbal Plants as an Effort to Prevent Degenerative Diseases to the Community Masfria; Muchlisyam; Julia Reveny; Hafid Syahputra
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 1 (2023): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/abdimastalenta.v8i1.9518

Abstract

This community service aims to increase public knowledge in health and health efforts through promotive and preventive activities by conducting counselling and training in the use of medicinal plants and how to process herbal plants properly and correctly so that people in Ndokum Siroga village, Karo Regency understand the importance of health and a healthy paradigm. by using herbal plants. This community service activity is to increase public awareness of health by introducing a healthy paradigm. The implementation method used is lectures and training where lectures are conducted to increase public knowledge about the health paradigm and the importance of health as well as the introduction of herbal plants to make family medicinal plants while the training is carried out by providing facilities and infrastructure for community service activities to increase community knowledge and skills, including delivery papers on various types of herbal plants used, things to consider in-plant processing, and their properties, as well as the practice of processing plants into drinks that are easy to consume. The conclusion of this activity is very helpful and provides good benefits to the community because this activity can have a direct impact on the community. The analysis technique and activity results are seen from the knowledge of the community before and after the training and counselling by asking questions in an objective form that can describe the different levels of understanding of the participants.
Training on Manufacture of Processed Cassava to Improve the Economy in Serasi Jaya Farmer Group Julia Reveny; Masfria; Hafid Syahputra; Nur Aira Juwita; Ade Sri Rohani
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 1 (2023): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/abdimastalenta.v8i1.9525

Abstract

Cassava (Manihot utilissima) is a local food commodity that is widely cultivated in Indonesia. The advantages of this plant are rich in carbohydrates, long harvest range, capable of producing in less fertile or infertile soils. However, cassava peel waste is still rarely processed into more useful products. Therefore, it is necessary to make efforts to increase the utilization of cassava peels into innovative products by conducting counseling and training in the manufacture of processed body scrubs with cassava peels as a base material to utilize regional natural resources into products with higher economic value, especially in the Serasi Jaya Village Farmer Group. The people's glare is located in Sei Rampah District, Serdang Bedagai Regency, North Sumatra. The method of service activities is carried out by lectures and demonstrations/training. The results of this activity were very satisfying because participants were able to make and use cassava peels into innovative products, namely body scrubs which were useful as skin care cosmetics so that they could help improve the community's economy
Formulation and Evaluation of Antibacterial and Anti-Inflammatory Capsules Containing Phyllanthus emblica L. Fruit Nanoparticles Masfria; Sumaiyah; Hafid Syahputra; Marwin Witarman
Science and Technology Indonesia Vol. 8 No. 4 (2023): October
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2023.8.4.607-615

Abstract

Phyllanthus emblica fruit has diuretic, antibacterial, hepatoprotective, antitumor, hypocholesterolemic, antioxidant, and antiulcerogenic activities making it possible as a traditional medicine in capsule form. Capsule preparations have the advantage of covering the unpleasant taste and smell of medicinal ingredients, easy to swallow, so they are practical to use. This study aimed to formulate Phyllanthus emblica fruit nanoparticles in capsules and to test the antibacterial activity against Streptococcus mutans and Pseudomonas aeruginosa and anti-inflammatory activity by observing denaturation inhibition in vitro. The method used to manufacture Phyllanthus emblica fruit simplicia nanoparticles was used using a High Energy Ball mill grinding machine. Capsule formulation was carried out with various doses of nanoparticles (100, 150, and 200 mg). Evaluation includes weight uniformity and disintegration time. Test of its antibacterial activity against Streptococcus mutans and Pseudomonas aeruginosa and its anti inflammatory activity in vitro. The study found that all formulas could be made into capsules that met the evaluation test requirements. The results of the evaluation of disintegration time ranged from 6.17-11.33 minutes. For the evaluation results of weight uniformity, it was found that weight deviations in columns A1 and A2 were in the range between 0.9% to 2.8% and 0.9 to 1.3%. The study reports on the antibacterial activity of Phyllanthus emblica fruit nanoparticle capsules (PFNP) against Streptococcus mutans and Pseudomonas aeruginosa. The results indicate that PFNP exhibits a dose-dependent antibacterial effect, with inhibition zone diameters of 10.83 mm, 11.6 mm, and 12.63 mm observed at 100 mg, 150 mg, and 200 mg, respectively, against Streptococcus mutans. Similarly, PFNP demonstrated a dose-dependent antibacterial effect against Pseudomonas aeruginosa, with inhibition zone diameters of 10.7 mm, 11.4 mm, and 12.1 mm observed at doses of 100 mg, 150 mg, and 200 mg, respectively. PFNP capsules showed inhibition results with a value of 5.63%, 6.13%, and 6.80%. It was concluded that Phyllanthus emblica fruit nanoparticles (Phyllanthus emblica L.) could be formulated in capsule dosage forms with doses of 100 mg, 150 mg, and 200 mg; has antibacterial activity against Streptococcus mutans and Pseudomonas aeruginosa, and has no anti-inflammatory activity.
KAJIAN KARAKTERISASI SELULOSA MIKROKRISTALIN DARI KERTAS BEKAS DENGAN VARIASI KONSENTRASI ASAM KLORIDA hafid Syahputra; Sri Yuliasmi; Sumaiyah Sumaiyah
Parapemikir : Jurnal Ilmiah Farmasi Vol 11, No 2 (2022): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v11i2.3209

Abstract

Kandungan selulosa pada kertas HVS mencapai 90% dari beratnya. Salah satu turunan selulosa adalah selulosa mikrokristalin (MCC), dimanfaatkan sebagai eksipien untuk pencetakan tablet. Pembuatan MCC menggunakan asam klorida (HCl). Tujuan penelitian ialah memberikan informasi terkait proses pembuatan MCC dari kertas bekas dengan pengaruh konsentrasi HCl untuk alternatif lain pembuatan MCC dengan hasil yang optimal dari penggunaan HCl untuk hidrolisis. Metode penelitian ini dimana MCC diperoleh dengan memanaskan kertas dengan campuran NaN  dalam HN 3,5% dan NaOH 2% dalam S  2%. Diputihkan dengan NaOCl 3,5% dalam air. Lalu panaskan dengan NaOH 17,5%, kemudian dihidrolisis dengan HCl konsentrasi 1N; 2,5N; 5N dan 10N. Selulosa mikrokristal ditentukan karakteristiknya. Hasil rendemen MCC terbanyak pada konsentrasi 1 N sebesar 80,82%. Hasil karakterisasi seluruh MCC kertas bekas konsentrasi HCl dan Avicel PH 102 diperoleh adalah uji organoleptik yaitu berwarna putih, tidak berbau, dan tidak berasa. Sifat fiskokimia meliputi pH memenuhi persyaratan; kelarutan dalam air semuanya memenuhi persyaratan. Selanjutnya bobot jenis nyata hanya 10N dan Avicel PH 102 yang memenuhi persyaratan, bobot jenis mampat tidak memenuhi persyaratan. Analisis FT-IR seluruh konsentrasi MCC dan Avicel PH 102 menunjukkan kemiripan spektrum. Kesimpulan didapatkan bahwa seluruh seluruh MCC kertas bekas konsentrasi HCl dan Avicel PH 102 memilki karakteristik yang hampir sama, dan dapat digunakan sebagai alternatif selulosa mikrokristal.
Relationship between interleukin-6 (IL-6) levels and chest X-ray severity scoring in COVID-19 patients Kardiasyah, Alzi; Syarani, Fajrinur; Bihar, Syamsul; Lubis, Netty D.; Mutiara, Erna; Syahputra, Hafid
Narra J Vol. 4 No. 1 (2024): April 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i1.690

Abstract

The severity of coronavirus disease 2019 (COVID-19) may be measured by interleukin-6 (IL-6) and chest X-rays. Brixia score of the chest radiographs is usually used to monitor COVID-19 patients’ lung problems. The aim of this study was to demonstrate the relationship between IL-6 levels and chest radiographs (Brixia score) that represent COVID-19 severity. A retrospective cohort study was conducted among COVID-19 patients who had a chest X-ray and examination of IL-6 levels at H. Adam Malik General Hospital, Medan, Indonesia. A multinomial logistic regression analysis was conducted to evaluate the association between IL-6 levels and the severity of the chest radiograph. A total of 76 COVID-19 patients were included in the study and 39.5% of them were 60–69 years old, with more than half were female (52.6%). A total of 17.1%, 48.7%, and 34.2% had IL-6 level of <7 pg/mL, 7–50 pg/mL and >50 pg/mL, respectively. There were 39.5%, 36.8% and 23.7% of the patients had mild, moderate and severe chest X-rays based on Brixia score, respectively. Statistics analysis revealed that moderate (OR: 1.77; 95% CI: 1.05–3.32) and severe (OR: 1.33; 95% CI: 1.03–3.35) lung conditions in the chest X-rays were significantly associated with IL-6 levels of 7–50 pg/mL. IL-6 more than 50 pg/mL was associated with severe chest X-ray condition (OR: 1.97; 95% CI: 1.15–3.34). In conclusion, high IL-6 levels significantly reflected COVID-19 severity through chest X-rays in COVID-19 patients.
Analysis of Vitamin C (ascorbic acid) in Cucumis mel L. var reticulatus Naudin and Averrhoa bilimbi L. Fruit using UV-Vis Spectrophotometry Hafid Syahputra; Muhammad Rivai; Shafira Mahrani; Yasmeen Nazhifah
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 6 No. 2 (2023): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v6i2.13557

Abstract

Cucumis mel L. var reticulatus Naudin and Averrhoa bilimbi L. are known to possess significant chemicals that offer health benefits, including the presence of vitamin C. Vitamin C, classified as a water-soluble vitamin, possesses the potential to exert a significant influence in the prevention of several diseases. The objective of this experiment was to analyze the concentrations of vitamin C present in Cucumis mel L. var reticulatus Naudin and Averrhoa bilimbi L. using the UV-Vis spectrophotometry method. The test was performed qualitatively with FeCl3 reagen and quantitatively with 2,6-dichlorophenol indophenol using UV-Vis spectrophotometry. The results showed that the levels of vitamin C in Cucumis mel and Averrhoa bilimbi fruit were 44.523 mg/100g and 48.666 mg/100 g, respectively.