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The effect of ethanol extract of Sarang Semut plant (Hypnophytum formicarum) towards Angiogenesis for wound healing after tooth extraction: Experimental research on Marmot (Cavia cobaya) Putri, Sartika Amelia; Ismardianita, Efa
Padjadjaran Journal of Dentistry Vol 28, No 3 (2016): November
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

Introduction: Tooth extraction causing injuries, to accelerate wound healing was given medication. Drugs commonly used for wound healing after tooth extraction is povidone iodine act as bacteriostatic for all germs. Excessive use of povidone iodine can cause side effects such as itching, pain in the area around the wound, swelling and dermatitis, so it sought a safe substitute drugs derived from herbs. One of the herbs are often used by people in the Mentawai Islands is a Sarang Semuts root species of Hypnophytum formicarum. This study was aimed to determine the effect of sarang semutâs extract orally for angiogenesis in wound healing after tooth extraction. Methods: This research was experimental with posttest only control group design. Subjects were 48-animal marmots were divided into 4 groups, will be deprived of his left mandibular insisivus. Group I (control 0,5% CMC, treatment group II, III, IV with 4,65mg, and 9.3 mg 6,2 mg dose tuber ethanol extract dissolved anthill in CMC 0.5%), were given 3 ml orally, 3 times a day until the day of decapitation. Futher histological preprations made by HE staining and the observed area is apex, medial, servical,and lateral used 400x magnification. The data was analyzed with parametric test One-Way ANOVA, and to see the significance between dose used LSD test. Results: The results showed that the extract of sarang semut effect (p<0,05) on the angiogenesis in wound healing after tooth extraction. Conclusion: The most effective concentration was 4,65 mg.

The effect of ethanol extract of Sarang Semut plant (Hypnophytum formicarum) towards Angiogenesis for wound healing after tooth extraction: Experimental research on Marmot (Cavia cobaya) Putri, Sartika Amelia; Ismardianita, Efa
Padjadjaran Journal of Dentistry Vol 28, No 3 (2016): November 2016
Publisher : Universitas Padjadjaran

Introduction: Tooth extraction causing injuries, to accelerate wound healing was given medication. Drugs commonly used for wound healing after tooth extraction is povidone iodine act as bacteriostatic for all germs. Excessive use of povidone iodine can cause side effects such as itching, pain in the area around the wound, swelling and dermatitis, so it sought a safe substitute drugs derived from herbs. One of the herbs are often used by people in the Mentawai Islands is a Sarang Semut's root species of Hypnophytum formicarum. This study was aimed to determine the effect of sarang semut’s extract orally for angiogenesis in wound healing after tooth extraction. Methods: This research was experimental with posttest only control group design. Subjects were 48-animal marmots were divided into 4 groups, will be deprived of his left mandibular insisivus. Group I (control 0,5% CMC, treatment group II, III, IV with 4,65mg, and 9.3 mg 6,2 mg dose tuber ethanol extract dissolved anthill in CMC 0.5%), were given 3 ml orally, 3 times a day until the day of decapitation. Futher histological preprations made by HE staining and the observed area is apex, medial, servical,and lateral used 400x magnification. The data was analyzed with parametric test One-Way ANOVA, and to see the significance between dose used LSD test. Results: The results showed that the extract of sarang semut effect (p<0,05) on the angiogenesis in wound healing after tooth extraction. Conclusion: The most effective concentration was 4,65 mg.

The effect of ant-plant (Hydnophytum formicarum) ethanol extract on collagen fibers for wound healing after tooth extraction in the guinea pig (Cavia cobaya) Velanita, Siti; Ismardianita, Efa; Pascawinata, Andries
Padjadjaran Journal of Dentistry Vol 31, No 3 (2019): November 2019
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol31no3.19328

Introduction: Tooth extraction causes tissue damage around the socket. Wound healing is essential for repairing damaged tissues. One of the medicinal plants often used is ant-plant (Hydnophytum formicarum), which contains flavonoids, triterpenoids, saponins and tannins. This research was aimed to determine the effect of ant-plant ethanol extract on the density of collagen fibers for wound healing after tooth extraction in the guinea pig (Cavia cobaya). Methods: The type of research was true experimental with a post-test only control group design. The study used 48 male guinea pig divided into 4 groups. Experimental groups received lower left incisor extraction, the control group was orally administered with 0.5% CMC, and the treatment group was administered with ant-plant extract dissolved with 0.5% CMC with dose of 4.65 mg, 6.2 mg, and 9.3 mg respectively; each guinea pig was given 3 cc of the extract 3 times a day until the termination day. On day 3, 7, 14, and 21 respectively, the guinea pigs were terminated and to make the histological preparations. The difference in collagen fibers density of the two observation groups was tested with one-way ANOVA, and the LSD test to analyse the significance between groups. Results: Application of ant-nest ethanol extract showed significant effects on the density of collagen fibers in the wound healing process after tooth extraction. Results of the one-way ANOVA test showed significant value on all treatment groups (p < 0.05). There were also found significant differences between the control group and the treatment group (p < 0.05). Conclusion: Ant-plant (Hydnophytum formicarum) ethanol extract increase the collagen fibers density on the wound healing after tooth extraction with the effective dose of 4.65 mg.Keywords: Ant-plant, Hydnophytum formicarum, wound healing, collagen, guinea pig, Cavia cobaya.

MEMBANDINGKAN POLA SIDIK BIBIR SEBAGAI SARANA IDENTIFIKASI JENIS KELAMIN PADA SUKU MINANG DI FAKULTAS KEDOKTERAN GIGI UNIVERSITAS BAITURRAHMAH PADANG TAHUN 2017 Mardiah, Ainul; Firdaus, Firdaus; Ismardianita, Efa
B-Dent: Jurnal Kedokteran Gigi Universitas Baiturrahmah Volume 4, Nomor 2, Desember 2017
Publisher : Universitas Baiturrahmah

Pola sidik bibir dapat dipengararuhi oleh jenis kelamin dan ras. Tujuan dari penelitian ini adalah untuk melihat gambaran pola sidik bibir berdasarkan jenis kelamin pada suku minang di Fakultas Kedokteran Gigi Universitas Baiturrahmah Padang tahun 2017. Desain penelitian ini adalah deskriptif observasional. Populasi dari penelitian ini adalah individu yang berjenis kelamin laki-laki atau perempuan suku minang dari dua generasi pada mahasiswa preklinik angkatan 2013-2016 di Fakultas Kedokteran Gigi Universitas Baiturrahmah Padang tahun 2017 dengan 133 sampel penelitian dengan metode total sampling, waktu penelitian 29 Mei 2017 dengan pemeriksaan klinis. Analisis data ditampilkan dengan tabel distribusi frekuensi dan grafik distribusi frekuensi dengan menggunakan program Microsoft Excel. Hasil penelitian menunjukkan bahwa pada responden laki-laki didominasi pola sidik bibir tipe 4 yaitu 22 orang (53.7%) dan pada responden perempuan didominasi pola sidik bibir tipe 2 yaitu 42 orang (45.7%) di Fakultas Kedokteran Gigi Universitas Baiturrahmah Padang tahun 2017.

PENGARUH PEMBERIAN EKSTRAK CABAI RAWIT (Capsicum Frustences, L) TERHADAP BAKTERI Streptococcus Sp PADA SOKET PASCA PENCABUTAN GIGI Sari, Vivin Nola; Ismardianita, Efa
B-Dent: Jurnal Kedokteran Gigi Universitas Baiturrahmah Volume 5, Nomor 1, Juni 2018
Publisher : Universitas Baiturrahmah

Streptococcus sp adalah salah satu bakteri yang banyak ditemukan pasca pencabutan gigi, untuk itu pencegahan infeksi dapat dilakukan dengan memberikan terapi antibiotik. Cabe rawit (Capsicum Frustecens, L) adalah salah satu tanam herbal yang memiliki efek sebagai anti mikroba terhadap bakteri Streptococcus Sp. Tujuan penelitian ini adalah untuk mengetahui pengaruh pemberian ekstrak cabai rawit (Capsicum Frustecens, L) terhadap bakteri Streptococcus Sp pada soket pasca pencabutan gigi. Jenis penelitian adalah eksperimental laboratorium dengan rancangan Post test only control group design, sampel penelitian yang digunakan adalah koloni bakteri Streptococcus sp yang dikultur langsung dari soket pasien pasca pencabutan gigi. Pengenceran ekstrak cabai rawit (Capsicum Frustecens, L) yaitu menggunakan 4 konsentrasi (20%, 40%, 60% dan 80%). Data hasil penelitian di uji dengan one way anova. Hasil penelitian menunjukan nilai rata-rata konsentrasi 20% adalah (11,01 mm), konsentrasi 40% (18,45 mm), konsentrasi 60% (18,62 mm) dan pada konsentrasi 80% yaitu19,34 mm, uji Anova didapat nilai fhitung> ftabel yaitu 6,211>3.24 dan p=0,005<0,05, dapat disimpulkan ekstrak cabai rawit (Capsicum Frustecens, L) dapat menghambat pertumbuhan bakteri Streptococcus sp pada konsentrasi 20%, 40%, 60% dan 80%, uji LSD ekstrak cabai rawit (Capsicum Frustecens, L). Hasil penelitian pengaruh pemberian ekstrak cabe rawit (Capsicum Frustecens, L) terhadap bakteri Streptococcus Sp pada soket pasca pencabutan gigi dengan dosis yang efektif 40%.

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