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All Journal Jurnal Biologi Tropis Benih : Journal of Midwifery
Amelia Roza, Amelia
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Systematic Review: Cytotoxicity Test of Bioactive Compounds of Asteraceae Family Plant Extracts on HeLa Cell Line Yanti, Windi Nofri; Hulrahma, Mifta; Aprilia, Kharisma Annisa; Roza, Amelia; Ilham, Kurniadi; Maliza, Rita
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7007

Abstract

HeLa cancer cells are cervical cancer cells due to Human Papillomavirus (HPV 18) infection and thus have different properties from normal cervical cells. In recent decades, the number of plant species used in alternative medicine for cervical cancer-related purposes has increased. This systematic review aims to facilitate the review of the potential bioactive compounds of plant medicines and analyze how medicinal plants affect cancer cells. Scientific related questions, databases to be used, selection of keywords, inclusion and exclusion criteria, definition of results and conclusions of selected articles are all elements included in this research search strategy. Eight articles met the inclusion criteria and examined plant-derived compounds for their toxicity to HeLa cell lines. The bioactive compounds of this plant inhibit the growth of cancer cells.
The Relationship Between Adolescents' Knowledge About the Dangers of Drugs and Health Behavior Roza, Amelia; Sinaga, Rosa
Benih : Journal of Midwifery Vol. 1 No. 01 (2022): Benih : Journal of Midwifery
Publisher : Cattleya Darmaya Fortuna

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54209/benih.v1i01.250

Abstract

This study investigates the relationship between adolescent knowledge of drug dangers and health behavior at SMA Negeri 1 Panyabungan Selatan, Mandailing Natal Regency. Narcotics, whether plant-based, synthetic, or semi-synthetic, are often associated with addiction and dependence. The abuse and illicit trafficking of drugs have severe consequences, including damage to individuals, communities, and the nation's future. Approximately 200 individuals were suspected of involvement in drug-related activities, prompting a community-oriented approach to address the issue. Using a descriptive research design, this study employed a questionnaire as the research instrument and utilized accidental sampling to select 36 respondents from class XI Science students in 2022. Univariate analysis, conducted using the SPSS program, revealed varying levels of knowledge among respondents: 20 individuals (55.6%) exhibited good knowledge, 6 individuals (16.7%) had sufficient knowledge, and 10 individuals (27.8%) possessed poor knowledge regarding drug dangers. This study sheds light on the importance of understanding the relationship between adolescent knowledge of drug dangers and their health behavior, offering insights for interventions aimed at promoting informed decision-making and healthy lifestyles among youth.  
Co-Authors Aprilia, Kharisma Annisa Hulrahma, Mifta Ilham, Kurniadi Maliza, Rita Sinaga, Rosa Yanti, Windi Nofri