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M Atik Martsiningsih
Poltekkes Kemenkes Yogyakarta
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Pengaruh Pemberian Jus Buah Naga Merah (Hylocereus polyrhizus) Terhadap Kadar Trigliserida Tikus Putih (Rattus norvegicus) Hiperlipidemia Wira Surya Rizqi, Afrida; Widada, Subrata Tri; Martsiningsih, M Atik
Jurnal Teknologi Laboratorium Vol 3 No 1 (2014): 2014 (1)
Publisher : POLTEKKES KEMENKES YOGYAKARTA

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Abstract

Cardiovascular disease is a disease that causes the most deaths in the world. One of its main risk factor is triglyceride levels which make the emergence of plaque in coronary artery. Statin as an option drug in reducing triglyceride levels apparently reported to cause myopathy and kidney failure when used in a long term. Natural product like red dragon fruit began to be developed as a safer alternative. The content of various substances such as niacin, vitamin C and fiber in it useful as antihypertriglyceridemia. This study aims to determine the effect of red dragon fruit (Hylocereus polyrhizus) juice to the decrease of triglyceride levels in hyperlipidemic white rats (Rattus norvegicus). This study was an experimental study with pre and post test with control group design. The subjects were 24 male experimental animals (Rattus norvegicus) were divided into 4 groups: one positive control group given simvastatin 0.18 mg/ 200 gram of weight and three groups treated with red dragon fruit juice doses of 3.6; 5.4 and 7.2 gram/ 200 gram of weight. Then, data were analyzed escriptively with One-Way ANOVA test using SPSS 16.0 for Windows. Results with descriptive analysis obtained that mean of positive control’s pre-test triglyceride level was 104.80 mg/ dl and treatment groups I, II and III respectively 108.15 mg/ dl, 106.47 mg/ dl and 107.43 mg/ dl whereas positive control’s post-test triglyceride level was 51.09 mg/ dl and for the treatment groups were 94.64 mg /dl, 71.01 mg/ dl and 58.75 mg/ dl. One Way ANOVA test obtained p <0.05 which indicated the difference between the treatment of various doses of red dragon fruit juice to white rats’ triglyceride levels. Based on that, means there is the effect of various doses of red dragon fruit (Hylocereus polyrhizus) juice to the decrease of triglyceride levels in hyperlipidemic white rats (Rattus norvegicus).
Pengaruh Pemberian Jus Buah Naga Merah (Hylocereus polyrhizus) Terhadap Kadar Trigliserida Tikus Putih (Rattus norvegicus) Hiperlipidemia Rizqi, Afrida Wira Surya; Widada, Subrata Tri; Martsiningsih, M Atik
Jurnal Teknologi Laboratorium Vol 3 No 2 (2014): 2014 (2)
Publisher : POLTEKKES KEMENKES YOGYAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (319.942 KB)

Abstract

Cardiovascular disease is a disease that causes the most deaths in the world. One of its main risk factor is triglyceride levels which make the emergence of plaque in coronary artery. Statin as an option drug in reducing triglyceride levels apparently reported to cause myopathy and kidney failure when used in a long term. Natural product like red dragon fruit began to be developed as a safer alternative. The content of various substances such as niacin, vitamin C and fiber in it useful as antihypertriglyceridemia.This study aims to determine the effect of red dragon fruit (Hylocereus polyrhizus) juice to the decrease of triglyceride levels in hyperlipidemic white rats (Rattus norvegicus).This study was an experimental study with pre and post test with control group design. The subjects were 24 male experimental animals (Rattus norvegicus) were divided into 4 groups: one positive control group given simvastatin 0.18 mg/ 200 gram of weight and three groups treated with red dragon fruit juice doses of 3.6; 5.4 and 7.2 gram/ 200 gram of weight. Then, data were analyzed descriptively with One-Way ANOVA test using SPSS 16.0 for Windows.Results with descriptive analysis obtained that mean of positive control’s pre-test triglyceride level was 104.80 mg/ dl and treatment groups I, II and III respectively 108.15 mg/ dl, 106.47 mg/ dl and 107.43 mg/ dl whereas positive control’s post-test triglyceride level was 51.09 mg/ dl and for the treatment groups were 94.64 mg /dl, 71.01 mg/ dl and 58.75 mg/ dl. One Way ANOVA test obtained p <0.05 which indicated the difference between the treatment of various doses of red dragon fruit juice to white rats’ triglyceride levels. Based on that, means there is the effect of various doses of red dragon fruit (Hylocereus polyrhizus) juice to the decrease of triglyceride levels in hyperlipidemic white rats (Rattus norvegicus).
Gambaran Perbedaan Kadar Kolesterol Total Metode CHOD-PAP (Cholesterol Oxidase – Peroxsidase Aminoantypirin) Sampel Serum dan Sampel Plasma EDTA Widada, Subrata Tri; Martsiningsih, M Atik; Carolina, Stephanie Cicilia
Jurnal Teknologi Laboratorium Vol 5 No 1 (2016): 2016 (1)
Publisher : POLTEKKES KEMENKES YOGYAKARTA

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Abstract

Pemeriksaan laboratorium sangat diperlukan untuk membantu menegakkan diagnosa suatu penyakit dan memperoleh hasil pemeriksaan yang akurat. Pemeriksaan kadar kolesterol dapat membantu perubahan pola dan gaya hidup sehat, untuk menghindari makanan yang mengandung kolesterol tinggi berisiko meningkatkan kadar kolesterol darah. Pemeriksaan kadar kolesterol biasanya menggunakan sampel serum dan sampel plasma. Penelitian ini bertujuan untuk mengetahui hasil pemeriksaan kadar kolesterol dan gambaran perbedaan hasil kadar kolesterol total metode CHOD-PAP dari sampel serum dan plasma EDTA. Jenis penelitian yang dilakukan adalah uji deskriptif disajikan dalam bentuk tabel untuk mengetahui selisih rata-rata kadar kolesterol total sampel serum dan plasma EDTA dan grafik untuk mengetahui yang lebih tinggi. Hasil uji deskriptif didapatkan kadar kolesterol total dengan rata – rata sampel serum 157,76 mg/dl, sedangkan pemeriksaan kadar kolesterol dengan rata – rata sampel plasma EDTA 153,71 mg/dl. Berdasarkan data penelitian analisa uji deskriptif dinyatakan perbedaan hasil pemeriksaan kadar kolesterol total antara sampel serum dan plasma EDTA yaitu 9,7 %.
Gambaran Kadar Glukosa Darah Metode GOD-PAP (Glucose Oxsidase – Peroxidase Aminoantypirin) Sampel Serum dan Plasma EDTA (Ethylen Diamin Terta Acetat) Subiyono, Subiyono; Martsiningsih, M Atik; Gabrela, Denni
Jurnal Teknologi Laboratorium Vol 5 No 1 (2016): 2016 (1)
Publisher : POLTEKKES KEMENKES YOGYAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (486.451 KB)

Abstract

Pemeriksaan laboratorium sangat diperlukan untuk membantu menegakkan diagnose suatu penyakit dan memperoleh hasil pemeriksaan yang akurat. Pemeriksaan kadar glukosa darah dapat membantu perubahan pola dan gaya hidup sehat, untuk menghindari makanan yang mengandung glukosa tinggi berisiko meningkatkan kadar glukosa darah. Pemeriksaan kadar glukosa biasanya menggunakan sampel serum dan sampel plasma. mengetahui hasil pemeriksaan kadar glukosa darah dan gambaran perbedaan hasil kadar glukosa darah metode GOD-PAP dari sampel serum dan plasma EDTA. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian deskriptif dalam bentuk table untuk mengetahui selisih rata-rata kadar glukosa darah sampel serum dan plasma EDTA dan grafik untuk mengetahui yang lebih tinggi. Hasil pemeriksaan kadar glukosa darah dengan sampel serum rata – rata 103,7 mg/dl, sedangkan pemeriksaan kadar glukosa darah dengan sampel plasma rata –rata 101,3 mg/dl. Berdasarkan analisa uji deskriptif dinyatakan ada perbedaan hasil pemeriksaan kadar glukosa darah antara sampel serum dan plasma EDTA. Ada perbedaan hasil pemriksaan kadar glukosa darah metode GOD-PAP dengan menggunakan sampel serum dan plasma EDTA.
Co-Authors Afrida Wira Surya Rizqi, Afrida Afrida Wira Surya Rizqi, Afrida Wira Surya Denni Gabrela, Denni Stephanie Cicilia Carolina, Stephanie Cicilia Subiyono Subiyono, Subiyono Subrata Tri Widada, Subrata Tri