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All Journal Best Journal (Biology Education, Sains and Technology) Jurnal Penelitian Farmasi dan Herbal Jurnal Pengabdian Masyarakat Putri Hijau
Elysa Elysa
Institut Kesehatan Deli Husada
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Formulasi Dan Uji Efektivitas Sediaan Gel Ekstrak Etanol Daun Sambung Rambat (Mikhania mikranta) Sebagai Antiinflamasi Pada Tikus Putih Jantan Elysa Elysa; Sembiring Pintata; Barita Esman Dabukke
BEST Journal (Biology Education, Sains and Technology) Vol 6, No 1 (2023): Juni 2023
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v6i1.7090

Abstract

Latar Belakang: Peradangan merupakan respon normal akibat sistem kekebalan tubuh untuk mengeliminasi patogen, mencegah meluasnya kerusakan jaringan dan memperbaiki jaringan yang rusak akibat gejala patologis suatu penyakit, Tujuan: Mengetahui konsentrasi yang memberikan efektivitas sebagai antiinflamasi terhadap kulit putih pria tikus diinduksi dengan karagenan 1%. . Metode: Tanaman merambat diekstraksi menggunakan etanol 96% sebagai pelarut. Tikus wistar diadaptasi selama tujuh hari sebanyak 15 ekor. Tikus secara acak dibagi menjadi 5 kelompok. Kelompok I (kontrol negatif) berbasis gel, kelompok II (kontrol positif) gel voltaren, kelompok III ekstrak etanol tanaman merambat dengan konsentrasi 5%, kelompok IV ekstrak etanol daun tanaman merambat 10%, kelompok V ekstrak etanol daun tanaman merambat dari daun 15%. Semua kelompok perlakuan disublantasikan dengan karagenan 1%. Edema pada kaki tikus diukur pada 30 menit hingga 180 menit. Analisis data menggunakan metode one way ANOVA. Hasil: dari hasil penelitian menunjukkan bahwa masing-masing kelompok perlakuan mengalami penurunan inflamasi, pada 5 kelompok perlakuan, penurunan inflamasi yang paling baik adalah konsentrasi 15% yang paling baik dibandingkan voltaren gel dalam menurunkan inflamasi, Kesimpulan: ekstrak etanol tanaman rambat memiliki efek yang hampir setara dengan obat voltaren tetapi obat voltaren lebih efektif mengurangi peradangan
PENYULUHAN TENTANG PENGGUNAAN DAUN AFRIKA (Vernonia amygdalina Del.) SEBAGAI OBAT ASAM LAMBUNG DI PUSKESMAS TALUN KENAS Wahyudi Wahyudi; Anggun Syafitri; Elysa Elysa
Jurnal Pengabdian Masyarakat Putri Hijau Vol 2 No 1 (2021): Jurnal Pengabdian Masyarakat Putri Hijau
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (349.007 KB) | DOI: 10.36656/jpmph.v2i1.620

Abstract

Gastric ulcer is a disease characterized by the presence of ulcers on the gastric mucosal wall which if not treated properly can cause death. African leaves contain tannin compounds that can form a protective layer on ulcers, saponins activate mucous membrane protective factors, and flavonoids that can increase inflammation. prostaglandin production and reduce gastric HCL secretion, all of which play a role in healing gastric ulcers. knowledge about African leaves (varnonia magdolyna del) and the use of plants in the environment around the house that have medicinal properties are also still lacking. The solution offered to overcome this problem is to provide education about African leaf plants (varnonia magdolyna del) and their health benefits in the form of: this activity is carried out by delivering material to the community then a question and answer session is held to ensure that the community understands the material provided. Gastric acid disease is one of the diseases that is often found, weak treatment using synthetic drugs (natural ingredients that are processed in a modern way). Some of them are side effects caused by the high price of synthetic drugs which are not friendly to people with low economy, so knowledge about the use of medicinal plants is very important to have. The results of the counseling in the village of talun kenas are that there are many diseases and are often found in the community, both young and old, one of which is stomach acid. There has been a question and answer session process to ensure understanding of the community about the material presented. The addition of knowledge to the community regarding this extension is seen from the activeness of the community during a discussion session on the type of outreach to the community.
UJI AKTIVITAS MOISTURIZER PROBIOTIK PRODUK KECANTIKAN TERHADAP BAKTERI Propionibacterium acnes dan Staphylococcus epidermidis Nina Irmayanti Harahap; elysa elysa; nurul dahlia harahap
Jurnal Penelitian Farmasi & Herbal Vol. 8 No. 2 (2026): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i2.2948

Abstract

Acne is one of the most common skin disorders affecting adolescents and young adults, with severity ranging from mild to severe. The pathogenesis of acne is influenced by multiple factors, including the presence of skin microbiota, particularly Propionibacterium acnes and Staphylococcus epidermidis. Objective: This study aims to evaluate the effectiveness of probiotics formulated in a moisturizer gel in inhibiting bacterial activity without compromising their moisturizing function. Methods: This study employed an experimental design to evaluate the antibacterial activity of moisturizer gel formulations using the well diffusion method, with inhibition zone diameter as the measured parameter. Additionally, a moisturizing test was conducted on 18 volunteers with dry skin conditions. Results: The results demonstrated that all moisturizer gel formulations exhibited moderate antibacterial activity, with inhibition zone diameters ranging from 5 to 10 mm. The moisturizing test conducted on 18 volunteers indicated that all formulations maintained skin moisture within the normal range, with values between 30% and 50%. Conclusion: Based on the antibacterial activity test, it can be concluded that probiotic-containing moisturizer gels exhibit antibacterial properties. However, their effectiveness remains moderate, as indicated by the inhibition zone diameters within the range of 5–10 mm.
Co-Authors Barita Esman Dabukke Nina Irmayanti Harahap nurul dahlia harahap Pintata Sembiring Syafitri, Anggun Wahyudi Wahyudi