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PERBANDINGAN SEDIAAN SIRUP ANTIDIARE EKSTRAK DAUN SAWO (Manilkara zapota L.) DENGAN SEDIAAN SIRUP ANTIDIARE DI PASARAN TERHADAP MENCIT PUTIH (Mus musculus L.) Linta Meliala; Anggun Syafitri
Jurnal Penelitian Farmasi & Herbal Vol 4 No 1 (2021): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i1.746

Abstract

Background: the Sapodilla leaves (Manilkara zapota L.) contain chemical compounds of tannins and flavonoids which have antidiarrheal activity. Tannins are astringent and flavonoids inhibit intestinal motility which can reduce fluid and electrolytes. Methods: This purpose research is to determine the effectiveness and comparison of sapodilla leaf extract syrup with Diapet Kids syrup as antidiarrheal against white mice induced by castor oil. The research used experimental method, the sample was macerated using 70% ethanol as solvent. The thick extract was formulated in syrup dosage form, and stability test was carried out. The syrup doses used were 60 mg/kg BW, 90 mg/kg BW, and 120 mg/kg BW, syrup without extract as a negative control and Diapet Kids syrup as a comparison syrup. The effectiveness of antidiarrhea was carried out by using the diarrhea protection method for 6 hours and comparing the effectiveness of the sapodilla leaf extract syrup with the Diapet Kids syrup. The results of research : is showed that the stability of sapodilla leaf extract syrup met the standard requirements. The data analysis using one way ANOVA then continued with Tukey HSD test. The antidiarrheal activity of sapodilla leaf extract syrup at 90 and 120 mg/kg BW and Diapet Kids syrup have significant different with positive control and syrup of sapodilla leaf extract at 60 mg/kg BW dose (p < 0.05). The comparison of syrup of sapodilla leaf extract dose of 120 mg/kg BW with syrup Diapet Kids was not in significantly difference (p > 0.05). The Sapodilla leaf extract syrup at 90 and 120 mg/kg BW had antidiarrheal activity and Sapodilla leaf extract syrup at 120 mg/kg BW had no significant difference with Diapet Kids syrup (p > 0.05).
EDUKASI PEMANFAATAN DAUN KOPI ARABIKA (Coffea arabica L.) SEBAGAI PENURUN KADAR KOLESTEROL DALAM DARAH DI RSU SEMBIRING DELI TUA Linta Meliala; Anggun Syafitri; Masria Phetheresia Sianipar; Delisma Simorangkir; Pintata Sembiring; Sofia Eliasari Br Bangun
Jurnal Pengabdian Masyarakat Putri Hijau Vol 3 No 2 (2023): Jurnal Pengabdian Masyarakat Putri Hijau
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpmph.v3i2.1193

Abstract

Hiperkolesterolemia adalah suatu kondisi dimana kolesterol dalam darah meningkat diatas keadaan normal yang mana dapat menjadi salah satu faktoer resiko untuk penyakit kardiovaskular. Dalam menurunkan kadar kolesterol dalam darah, masyarakat sering memilih alternatif sebagai penyembuhan yaitu adalah obat-obatan. Obat-obatan sendiri terbagi menjadi dua jenis yaitu pengobatan secara konvensional dan pengobatan secara tradisional. Penggunaan obat tradisional untuk menurunkan kadar kolesterol masih sangat sedikit, sehingga dalam menurunkan kadar kolesterol darah masyarakat masih banyak menggunakan obat-obat konvensional, sehingga bahan alam sangat sia-sia karena tidak dimanfaatkan. Salah satu tanaman yang dapat menurunkan kadar kolesterol dalam darah adalah Daun Kopi Arabika yang memiliki kandungan senyawa berupa flavonoid, saponin, asam klorogenik yang mana dapat menurunkan kadar kolesterol. Daun Kopi Arabika sendiri banyak terdapat di dalam Indonesia. Tujuan dari PKM ini adalah untuk memberikan atau meningkatkan pengetahuan pasien dalam masa terapi rawat jalan utnuk pengobatan penyakit tingginya kadar kolesterol dalam darah di RSU Sembiring dengan metode edukasi tentang pemanfaatan Daun Kopi Arabika sebagai penurun kadar kolesterol dalam darah. Setelah mengikuti kegiatan sosialisasi ini, para peserta memiliki pengetahuan yang baru tentang pemanfaatan Daun Kopi Arabika sebagai penurun kadar kolesterol dalam darah, selain itu para peserta juga dapat mengeksekusi Daun Kopi Arabika menjadi suatu sediaan yang simple dan mudah digunakan.
UPAYA PENINGKATAN PENGETAHUAN HIPERTENSI KEPADA LANSIA DI PUSKESMAS NAMORAMBE Linta Meliala; Anggun Syafitri; Puji Lestari; Atika Patnisuri
Jurnal Pengabdian Masyarakat Putri Hijau Vol 3 No 4 (2023): Jurnal Pengabdian Masyarakat Putri Hijau
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpmph.v3i4.1518

Abstract

Promotive health development is one way to increase public knowledge. Hypertension is a condition that is often found and is the highest cause of death in the world. Hypertension is a condition that is often found and is the highest cause of death in the world. The purpose of this community service activity is for the community to have, understand and maximize knowledge about hypertension. The method carried out is in the form of two-way counseling using a power point instrument containing hypertension material and questionnaires before and after counseling. The target of this activity is the village community of 30 people. The implementation time will be on Saturday, June 10, 2023, located at the Namorambe Health Center. After counseling activities and questionnaire tests, it showed an increase in public knowledge about hypertension to 82%. Increasing good knowledge is expected to make people more aware and able to apply this knowledge in their daily lives.
SAKU SEHAT MILENIAL : EDUKASI PEMANFAATAN PARE (Momordica charantia L.) DAN BUNGA ROSELLA (Hibiscus sabdariffa L.) DALAM MENGOBATI DIABETES DI MADRASAH ALIYAH SWASTA AL-WASHLIYAH 30 BINJAI Syafitri, Anggun; Rahmi, Sofia; Hayati, Silmi; Tamba, Agnes Clara; Br Barus, Lidia Klorida
Jurnal Pengabdian Masyarakat Putri Hijau Vol 4 No 1 (2023): Jurnal Pengabdian Masyarakat Putri Hijau
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpmph.v4i1.1633

Abstract

Diabetes melitus merupakan penyakit gangguan metabolik yang disebabkan oleh gagalnya organ pankreas dalam memproduksi hormon insulin secara memadai. Terapi farmakologi diabetes melitus saat ini masih terbatas pada penggunaan obat-obatan seperti hipoglikemik oral (OHO) dan masyarakat yang menderita diabetes sebagian besar melakukan swamedikasi dengan obat tradisonal yang digunakan bersamaan dengan obat antidiabetes sintesis. Salah satu contoh tanaman yang dapat menurunkan kadar glukosa darah adalah buah pare dan bunga rosella yang memiliki kandungan flavonoid untuk menurunkan glukosa darah dengan cara meningkatkan sensitivitas sel terhadap insulin dan merangsang pelepasan insulin pada sel β pancreas. Tujuan dari kegiatan ini adalah untuk memberikan edukasi kepada siswa Madrasah Aliyah Swasta Al-Washliyah tentang obat antidiabetes yang berasal dari bahan alam yaitu buah pare dan bunga rosella. Setelah mengikuti kegiatan ini peserta memiliki pengetahuan yang baru tentang cara pengolahan bahan alam seperti buah pare dan bunga rosella sebagai terapi pengobatan diabetes melitus yang aman dan efektif.
Pengenalan Tumbuhan Lokal Untuk Kosmetik Kepada Gen Z : Edukasi Formulasi Sediaan Pomade Estrak Daun Meniran ((Phyllanthus Niruri L ) Sebagai Perangsang Penumbuh Rambut Syafitri, Anggun; Rahmi, Sofia; Tamba, Agnes Clara; Hayati, Silmi
Jurnal Pengabdian Masyarakat Putri Hijau Vol 4 No 3 (2024): Jurnal Pengabdian Masyarakat Putri Hijau (JPMPH)
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpmph.v4i3.1828

Abstract

Health Vocational High School is a place of education where students study. Busy student activities can sometimes reduce students' knowledge regarding the use of natural materials. The method applied in community service activities is providing counseling and education in the form of lectures and questions and answers directly by practicing making pomade cosmetics. Students' lack of knowledge regarding the use of natural ingredients from meniran leaves (Phyllanthus niruri L) as the main ingredient in natural pomade cosmetics which functions as a hair growth stimulant. For this reason, students are given education and understanding about the formulation of meniran leaf extract pomade preparations. The aim of holding service activities for students is "Introducing Local Plants for Cosmetics to Gen Z: Education on the Formulation of Meniran Leaf Extract Pomade Preparations as a Hair Growth Stimulator". To provide knowledge and understanding to Dewantara Husada Health Vocational School students regarding the introduction of local plants for cosmetics in the formulation of meniran leaf extract pomade as a hair growth stimulant. The conclusion of this PKM activity was carried out using the lecture and question and answer method, and practice. Based on the high level of participation in this PKM activity, it was classified as very good, participants in the question and answer session were considered to have a special interest in the material
GAMBARAN UMUM PASIEN RAWAT JALAN DI RUMAH DAN EVALUASI PELAYANAN INFORMASI OBAT DI INSTALASI FARMASI RUMAH SAKIT UMUM SEMBIRING DELI TUA Syafitri, Anggun; Marbun, Viktor Edyward
Jurnal Penelitian Farmasi & Herbal Vol 6 No 1 (2023): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Drug Information Service (PIO) is one of the standards that must be applied to improve the best pharmaceutical services. Drug information services are very necessary for patients because complete drug information can determine the success of self-therapy at home, especially for outpatients. Provision of drug information has an important role to achieve optimal treatment results, Provision of drug information has an important role to achieve optimal treatment results, so as to improve the quality of life of patients. Pharmaceutical services at this time have shifted their orientation from drugs to patients referring to pharmaceutical care. This study used a descriptive observational research method with a cross sectional design and used a quantitative approach. This research was conducted at the Outpatient Installation of Sembiring Deli Tua General Hospital. The population is the entire object used in the study.
Formulasi Sediaan Pomade Ekstrak Daun Meniran (Phyllanthus niruri L.) Sebagai Perangsang Penumbuh Rambut Pada Kelinci Syafitri, Anggun; Marbun, Viktor Edyward; Laia, Sardamai
Jurnal Penelitian Farmasi Dan Herbal Vol 6 No 2 (2024): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v6i2.1688

Abstract

Background: Meniran petroleum ether extract 2% which contains lignans and terpenoids can increase hair growth activity by inhibiting 5α-reductase. In addition, the ethanol extract of candlenut seeds from the same family as meniran Flavonoids and phenols can also stimulate hair growth. Previous studies have also shown that quercetin also has activity to increase hair growth. Meniran is also known to contain the flavonoids quercetin, nirurin, rutin, quercitrin, astragalin and galocatechin. So meniran ethanol extract was chosen for this study. Based on a literature search about this research, the researcher was interested in formulating meniran leaf extract pomade (Phyllanthus niruri L.) as a hair stimulant in rabbits (Oryclolagus cunucilus). Purpose: To determine the formulation of meniran leaf extract pmade (Phyllanthus niruri L.) which is good in stimulating hair growth in rabbits. Methods: The method used was an experimental study to test the characteristics of pomade preparations with meniran leaf extract concentrations of 5%, 7.5% and 10% with organoleptic, homogeneity, spreadability, pH, irritation and freeze-thaw parameters. Results: From the results of the research on the characteristic test of pomade preparations on formulations of formula I, formula II and formula III it was found that they fulfilled the characteristics of pomade while F0 did not meet the spreadability requirements. Conclusion: Among the three formulations, it was found that pomade with formula III had the effectiveness of a good hair growth stimulant and could compete with the positive control.
HUBUNGAN PERSONAL HYGIENE DAN PENGGUNAAN ALAT PELINDUNG DIRI (APD) DENGAN KEJADIAN DERMATITIS KONTAK PADA PETUGAS PENGANGKUT SAMPAH DI TEMPAT PEMBUANGAN AKHIR (TPA) TADUKAN RAG MARBUN, VIKTOR EDYWARD; Sembiring, Johannes; syafitri, anggun
Jurnal Penelitian Keperawatan Medik Vol 6 No 1 (2023): JURNAL PENELITIAN KEPERAWATAN MEDIK
Publisher : Fakultas Keperawatan Institut Kesehatan Deli Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpkm.v6i1.1597

Abstract

Contact dermatitis is dermatitis caused by the presence of irritants or allergens attached to the skin. Epidemiological data in Indonesia shows that 97% of 389 cases of skin disease are contact dermatitis, 66.3% of these cases are irritant contact dermatitis and 33.7% are allergic contact dermatitis. This study aims to determine the relationship between personal hygiene and the use of personal protective equipment (PPE) with the incidence of contact dermatitis in waste collectors at the Tadukan Raga Deli Serdang final disposal site (TPA) in 2023. This study used a quantitative approach with a cross sectional study design. The research was conducted in March 2023 – June 2023 at the Tadukan Raga landfill in Tanjung Morawa. The population of this study were all garbage collectors at the Tadukan Raga TPA. The number of samples in this study were 43 people with the sampling technique being total sampling. Data was collected using a questionnaire with interviews. Data analysis was performed univariately and bivariately with the chi-Square test. The results showed that the variables associated with the incidence of contact dermatitis were: personal hygiene (pvalue=0.004), personal protective equipment (pvalue=0.013). There is a relationship between personal hygiene and the use of personal protective equipment (PPE) with the incidence of contact dermatitis.
FORMULASI DAN UJI EFEKTIVITAS SEDIAAN EKSTRAK ETANOL KULIT PEPAYA (Carica papaya L) SEBAGAI BRIGHTENING GEL SERUM Syafitri, Anggun; Sianipar, Masria Phetheresia; Fantika, Ardhana
Jurnal Penelitian Farmasi Dan Herbal Vol 7 No 1 (2024): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v7i1.1998

Abstract

Facial skin problems that often occur in women and adolescents are dull skin and dark looking skin. Papaya peel (carica papaya L) contains flavonoid compounds which function as antioxidants to brighten the skin. This study aims to formulate papaya peel extract into a serum gel dosage form and observe its effectiveness on the skin of volunteers for 4 weeks of treatment. The research was started by making papaya peel extract which was obtained by maceration method. Then the extract was formulated into serum gel preparations with varying concentrations of gelling agent Carbomer 940 4%, 5%, 6%. The preparations were eval_uated for their physical characteristics, namely organoleptic test, pH test, spreadability test, viscosity test, homogeneity test, irritation test, and test volunteer. The results showed that papaya peel extract could be formulated into a serum gel preparation that was homogeneous, light brown in color, had a spreadability of <5 cm, with a pH <6, and had a viscosity of >2000 cps. Serum gel formula containing Carbomer 940 with a concentration of 6% which has the best effectiveness.
UJI EFEKTIVITAS HIPERKOLESTEROLEMIA EKSTRAK ETANOL DAUN KECIPIR (Psophocarpus tetragonolobus L) PADA TIKUS PUTIH JANTAN (Rattus norvegicus) YANG DIINDUKSI KUNING TELUR BEBEK sianipar, masria phetheresia; Syafitri, Anggun; Sembiring, Pintata
Jurnal Penelitian Farmasi Dan Herbal Vol 7 No 1 (2024): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v7i1.2074

Abstract

This study explored the effectiveness of winged leaf ethanol extract (Psophocarpus tetragonolobus L) in lowering cholesterol levels in male white rats (Rattus norvegicus) induced with duck egg yolk. An experimental method was used to eval__uate the impact of the extract on cholesterol levels, with the aim of providing an alternative treatment of hyperglycoleemia based on natural ingredients. The results show the significant potential of the extract. This research method uses an experimental approach with laboratory design. Male white rats (Rattus norvegicus) were divided into treatment and control groups. Winged leaf ethanol extract was administered to the treatment group, while the control group did not receive the treatment. Cholesterol level measurements were carried out after induction with duck egg yolk, to eval__uate the effectiveness of the extract in lowering cholesterol levels. The results showed that the administration of winged leaf ethanol extract significantly reduced total cholesterol, LDL, and triglyceride levels in induced male white rats. The group that received the highest dose of the extract showed the most favorable reduction in cholesterol levels, close to the effects of simvastatin. These findings indicate the potential of winged leaves as an alternative in the management of hypercholesterolemia. The conclusion of this study showed that winged leaf ethanol extract (Psophocarpus tetragonolobus L) was effective in lowering cholesterol levels in induced male white rats. A dose of 300 mg/kgBB has been shown to be the most effective. Recommendations for further research are to explore different dosage forms and extract concentrations, as well as conduct toxicity studies to ensure their safe use as a hypercholesterolemia therapy.