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All Journal Jurnal EduHealth
Nuroh Najmi
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Health Professions Public Health Veterinary

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The Role Of Entamoeba Gingivalis In Periodontal Disease: A Literature Study Emma Rachmawati; Rizky Farida Berlian; Ina Hendiani; Nuroh Najmi; Achmad Syawqie
Jurnal EduHealth Vol. 14 No. 02 (2023): Periode April-June, 2023
Publisher : Sean Institute

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Abstract

Background: Periodontal disease can affect the supporting structures of the teeth and can cause tooth loss. Periodontal disease is caused mainly by bacteria in dental plaque, but protozoa can also be found in deep pockets. The most common protozoa existing in periodontal disease is Entamoeba gingivalis. This study aims to determine the role of E. gingivalis in periodontal disease. Method: This research was a rapid review which is a method of synthesizing and assessing existing research. Articles were searched using the PubMed database from February 2021 to April 2021 with inclusion criteria in English from 2010 to 2020 and discussing the presence of E. gingivalis in periodontal disease. Result: Articles that comply with the inclusion criteria of this study are 11 articles. The study designs included case-control, cross-sectional, cohort, and case series. All articles concluded that E. gingivalis was found in patients with periodontal disease. Conclusion: The presence of E. gingivalis in large numbers in inflamed periodontal tissues indicates that E. gingivalis has a role in the course of periodontal disease.
Dental Biofilm Formation: A Scoping Review Febriane Balafif, Felisha; Anggun Rafisa; Faisal Kuswandani; Nuroh Najmi
Jurnal EduHealth Vol. 16 No. 03 (2025): Jurnal EduHealt, Edition July - September , 2025
Publisher : Sean Institute

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Abstract

Dental biofilm is a structured microbial community that adheres to the tooth surface and becomes embedded within a self-produced extracellular matrix. This matrix, rich in polysaccharides, proteins, and nucleic acids, enables microorganisms to survive environmental stresses and contributes to the onset of oral diseases such as caries and periodontitis. The purpose of this scoping review is to determine current knowledge the dental biofilm formation. The articles published from 2020 until 2025 were searched for using the keywords: "dental and biofilm and formation" in the PubMed, ScienceDirect, and Google scholar databases. Using PRISMA-Scr, existing articles were chosen based on inclusion and exclusion criteria. There were five articles found that were suitable for review. The data presented in the article vary according to the study's location, purpose, method, and samples. The major classes of extracellular polymeric substances that form the matrix are common to most biofilms and comprise carbohydrates, proteins, nucleic acids, and cell wall polymers, such as peptidoglycans and lipids. Several unique resistance mechanisms make biofilms particularly tough to manage. Biofilm bacteria employ multiple defense mechanisms, such as capsule protection, efflux pumps, membrane modifications, genetic adaptations, quorum sensing, metabolic dormancy, and stress responses, making them highly resistant to treatment and contributing to persistent infections.
Co-Authors Achmad Syawqie Anggun Rafisa Faisal Kuswandani Febriane Balafif, Felisha Ina Hendiani Nurwijayanti Rizky Farida Berlian