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Lie T. Merijanti, Lie T.
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Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Dietary fat and cardiovascular disease? Merijanti, Lie T.
Universa Medicina Vol 34, No 3 (2015)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2015.v34.159-160

Abstract

Dietary saturated fat (SF) intake has been shown to increase low density lipoprotein (LDL) cholesterol and therefore has been associated with increased risk of cardiovascular disease (CVD). This evidence coupled with inferences from epidemiologic studies and clinical trials, had led to longstanding public health recommendations for limiting SF intake as a means of preventing CVD. However the relationship between SF and CVD risk remains controversial, due at least in part to the intrinsic limitations of clinical studies that have evaluated this relationship. A recent meta analysis showed that current evidence does not clearly support cardiovascular guidelines that encourage high consumption of polyunsaturated fatty acids (PUFA) and low consumption of total SF. They found weak positive associations between circulating palmitic and stearic acids (found largely in palm oil and animal fats, respectively) and CVD, whereas circulating margaric acid (a dairy fat) significantly reduced the risk of CVD.(2,3) Saturated fat are not associated with all cause mortality, CVD, CHD, ischemic stroke or type 2 diabetes, but the evidence is heterogenous with methodological limitations.
Body mass index as predictor of carpal tunnel syndrome among garment workers Merijanti, Lie T.
Universa Medicina Vol 28, No 3 (2009)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2009.v28.146-151

Abstract

Of the nerve entrapment syndromes the most well-known is the carpal tunnel syndrome (CTS) involving the median nerve. In the field of occupational medicine this condition is categorized as an occupational disease, for which industrial workers may claim compensation if the CTS occurs as a consequence of their job. However, although several occupational risk factors have been suggested as causing the development of CTS, a definitive role of work activities as the central cause of CTS is unclear. The aim of the present study was to evaluate both non-occupational and occupational factors associated with CTS in garment home-industry workers. A cross-sectional study was performed from April to June 2008 in the garment home industry in North Jakarta. A total of 99 workers, consisting of 45 males and 54 females were included in this study. Historical data were obtained from a self-administered detailed questionnaire, while anthropometric and provocative median nerve test variables were measured directly. The results showed that body mass index (BMI) was a significant predictor of CTS in male workers (p=0.031), while the risk of CTS was three-fold higher in female workers using hormonal contraceptives (Prevalence Ratio/PR = 3.3 ; 95% Confidence of Interval/CI = 1.0 – 10.5). In conclusion it appears that BMI and hormonal contraceptive use were CTS predictors.
The role of night shift work on blood pressure among healthy female nurses Merijanti, Lie T.; Samara, Diana; Tandean, Reza; Harrianto, Ridwan
Universa Medicina Vol 27, No 2 (2008)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2008.v27.65-71

Abstract

Although hypertension is probably the most common disease on earth, little is known about the association between shift work and hypertension. The aim of this study was to determine the relationship of night shift work and blood pressure among healthy nurses. A cross-sectional study was performed from March to April 2007 among 152 healthy female nurses from one hospital in Central Jakarta. Historical data were obtained from a self-administered detailed questionnaire, while anthropometric and blood pressure variables were measured directly. Shift workers had a significantly lower age (29.2 ± 5.6 years) and shorter job experience (6.9 ± 5.9 years) than day workers (age = 36.5 ± 8.7 years; job experience 15.4 ± 8.4 years). There was a higher prevalence of overweight individuals among shift workers (31/43 = 72.1%) in comparison with day workers (12/43 = 27.9%), even though the difference in prevalence did not reach statistical significance (p=0.121). Analysis of covariance yielded a significant relationship between shift work and systolic blood pressure (p=0.046), even after taking into account age and job experience. Systolic blood pressure was significantly influenced by shift working, while diastolic blood pressure was not (p=0.283). Working in the hospital on a 24-hour shift leads to abnormally high systolic blood pressure in female nurses, thus suggesting that this type of work may be a risk factor for cardiovascular disease.
Novel swine origin influenza a (H1N1) virus in humans Merijanti, Lie T.
Universa Medicina Vol 28, No 1 (2009)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2009.v28.i-ii

Abstract

In March and early April 2009, while much of the world was focusing on the threat of avian influenza originating in Asia, intelligence gathering systems were also extracting evidence of an epidemic of acute respiratory infections in Mexico and southern California. Although the exact sequence of events is uncertain, the Centers for Disease Control and Prevention (CDC) had confirmed the presence of a novel reassortment of Influenza A strain H1N1 from avian, swine, and human strains. On 25 April 2009, The World Health Organization (WHO) declared the swine flu outbreak in North America a public health emergency of international concern. On 29 April 2009, the International Health Regulations emergency committee recommended a change from WHO pandemic influenza phase 4 to phase 5. This means that WHO views a pandemic as imminent. WHO and the CDC have confirmed that the new swine flu virus is transmitted between humans.
PENGARUH PENGGUNAAN RISPERIDONE TERHADAP INDEKS MASSA TUBUH PADA PASIEN SKIZOFERNIA Fabian, Jose; Merijanti, Lie T.
Jurnal Kesehatan Tambusai Vol. 7 No. 1 (2026): MARET 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v7i1.55015

Abstract

Skizofrenia merupakan gangguan mental kronis yang ditandai oleh gejala psikosis dan memerlukan terapi jangka panjang, salah satunya menggunakan risperidone. Meskipun efektif dalam mengontrol gejala, risperidone diketahui berpotensi menyebabkan perubahan metabolik, termasuk peningkatan indeks massa tubuh (IMT). Beberapa penelitian menunjukkan adanya kenaikan berat badan yang signifikan pada tahap awal terapi, namun temuan lain justru tidak menemukan perubahan bermakna, sehingga diperlukan kajian lebih lanjut. Penelitian ini bertujuan mengevaluasi apakah penggunaan risperidon berkaitan dengan perubahan IMT pada pasien skizofrenia. Penelitian dilakukan di RS Ernaldi Bahar, Palembang, antara Agustus dan November 2025, dengan desain observasional analitik dan potong lintang (cross-sectional). Sebanyak 89 pasien yang menggunakan risperidon dan memiliki data tinggi serta berat badan terbaru dimasukkan ke dalam studi. Data dikumpulkan dari rekam medis serta pengukuran langsung, kemudian dianalisis menggunakan uji Wilcoxon Signed-Rank Test. Hasil penelitian menunjukkan mayoritas responden berada pada usia 18–59 tahun (93,3%) dan berjenis kelamin laki-laki (74,2%). Uji statistik menunjukkan adanya perbedaan bermakna antara IMT sebelum dan sesudah penggunaan risperidone dengan nilai p < 0,001, di mana 67 dari 89 pasien mengalami peningkatan IMT. Temuan ini menunjukkan bahwa risperidone berhubungan dengan perubahan IMT secara signifikan pada populasi penelitian. Berdasarkan hasil penelitian, penggunaan risperidone berpengaruh terhadap peningkatan IMT pada pasien skizofrenia, sehingga pemantauan status nutrisi perlu dilakukan secara berkala untuk mencegah risiko metabolik jangka panjang.
Co-Authors Fabian, Jose Reza Tandean Ridwan Harrianto, Ridwan Tjam Diana Samara