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All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Universa Medicina JURNAL PENGABDIAN KEPADA MASYARAKAT Jurnal Biomedika dan Kesehatan JURNAL ILMIAH KESEHATAN SANDI HUSADA Medika Kartika : Jurnal Kedokteran dan Kesehatan Jurnal Ilmiah Kesehatan Masyarakat : Media Komunikasi Komunitas Kesehatan Masyarakat Jurnal Penelitian dan Karya Ilmiah Lembaga Penelitian Universitas Trisakti Jurnal AKAL: Abdimas dan Kearifan Lokal Jurnal Lentera Kesehatan Masyarakat (JLKM) Jurnal Pengabdian Masyarakat Trimedika Jurnal Ilmiah Kesehatan Sandi Husada
Tjam Diana Samara
Department Of Anatomy, Faculty Of Medicine, Universitas Trisakti/Department Of Occupational Medicine, Faculty Of Medicine, Universitas Trisakti, West Jakarta, Indonesia
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Manual handling as risk factor of low back pain among workers Harrianto, Ridwan; Samara, Diana; Tjhin, Purnamawati; Wartono, Magdalena
Universa Medicina Vol 28, No 3 (2009)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2009.v28.170-178

Abstract

Disorders of the musculoskeletal system constitute a considerable health problem in industrialized societies. Low back pain (LBP) remains a common and costly problem among the workers. Workplace injuries, primarily musculoskeletal disorders, are a persistent problem for nursing. A cross-sectional study was conducted to investigate prevalence of LBP as well as the potential risk factors associated with LBP. These potential risk factors include individual characteristics, job duration, type of work, and manual handling knowledge and practice. Seventy-six subjects consisting of 30 nurses and 46 administrative workers were recruited into the study. Symptoms of LBP cases were assessed by means of a simple questionnaire, and the diagnosis of LBP was confirmed by clinical examination. The study showed that the overall point prevalence rate of LBP was 42.1%, while the overall 12-month prevalence rate was 69.7%. Occupational group and manual handling practice were independent predictors for point prevalence of LBP. Nursing occupation significantly increased the risk of point prevalence rate of LBP by 2.703 (95% C.I. OR 1.046 – 6.984) compared to administrative workers. Nurses with frequent manual handling practice had a 2.917-fold higher risk of developing a point prevalence of LBP, although this risk was statistically not significant (OR=2.917;95% C.I. 0.094-3.003). The study indicates that an association exists between manual handling practice and LBP prevalence.
The association between shift work and body mass index among female nurses Samara, Diana; Merijanti, Lie T; Tandean, Reza; Harrianto, Ridwan
Universa Medicina Vol 27, No 2 (2008)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2008.v27.72-77

Abstract

Possibly due to a disturbance of biological rhythms, shift work is associated with several health problems, particularly an increased risk of coronary heart disease (CHD). Obesity is a well known independent cardiovascular risk factor and has been shown to be more prevalent among shift workers. The objective of this study was to examine the association between shift work and body mass index in nurses working in one hospital in Central Jakarta. A cross-sectional study was conducted among 152 female nurses, ranging from 22 to 55 years of age, with determination of body mass index (BMI), and systolic and diastolic blood pressure (SBP and DBP). The results show a mean age of 30.9 ± 7.2 years and mean job experience of 8.9 ± 7.6 years. There was no significant difference in the prevalence of gastrointestinal disorders between shift and day workers. Mean BMI (23.1 ± 3.6) and mean job experience (6.9 ± 5.9 years) in shift nurses were significantly different from those in day workers (BMI = 24.8 ± 3.8; job experience 15.4 ± 8.4 years). In shift working nurses the BMI increased significantly in proportion to job experience (p=0.014). In conclusion, the present study has proven that job experience significantly increased BMI in shift working nurses.
Restless legs syndrome and impact on work performance Samara, Diana
Universa Medicina Vol 28, No 1 (2009)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2009.v28.42-48

Abstract

Restless legs syndrome (RLS) is a neurological sensorimotor disorder characterized by unpleasant sensations in the legs and an uncontrollable urge to move them for relief. The RSL prevalence in the general population is 0.1% - 11.5%, and increases with age, with the highest effect of producing a primary sleep disorder (70%-80%). Women appear to be at increased risk, as do individuals with certain chronic conditions, including renal failure and anemia. The pathophysiology of RLS is incompletely understood, but it probably results from derangements in dopamine and iron metabolism, and has a genetic component. RSL could be idiopathic or secondary (usually related with iron deficiency, terminal renal failure, pregnancy, and spinal cord lesions). RLS patients usually have sleep disorders, so the disease can cause difficulties and problems in occupational and social life. Subjects with RLS symptoms appear to experience significantly more daytime problems, including being late for work, making errors at work, or missing work because of sleepiness. The diagnosis of RLS is made by following the criteria of the International Restless Legs Syndrome Study Group (IRLSSG). Pharmacologic RLS therapy, in which dopaminergic drugs constitute the first line, is effective and may have a dramatic effect on symptoms and quality of life. Identifying and treating RLS may improve sleep quality, daytime function and work performance.
Prognosis and management of polymyalgia rheumatica Samara, Diana
Universa Medicina Vol 30, No 1 (2011)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2011.v30.63-70

Abstract

Polymyalgia rheumatica (PMR) is commonly found in Northern Europe and in persons of Scandinavian extraction in the US, with an annual incidence of around 50 per 100,000 population over 50 years of age, in whom it should be           considered in the differential diagnosis of musculoskeletal disorders. The     disorder is twice more common in women than in men. PMR is closely related to giant cell arteritis and both disorders are considered to have a common    pathogenesis, associated with genetic and environmental factors (viral and   bacterial infections). There is no gold diagnostic standard for PMR and the diagnosis rests on a high index of suspicion in persons older than 50 years with musculoskeletal symptoms. As an aid in diagnosis, several sets of diagnostic criteria have been used, usually related to age at onset, duration, symptoms, inflammatory markers, and response to corticosteroids. Patients with PMR   usually present with acute onset of stiffness and pain in the shoulder and pelvic musculature, which may be accompanied by fever, malaise, and weight loss. The symptoms of PMR seem to be related to synovitis of proximal joints and extra-articular synovial structures. PMR may occur as an isolated syndrome or accompany other diseases, mainly giant cell arteritis. It usually responds quickly to once-daily, low-dose prednisone, but some patients require treatment for  several years. Monitoring for corticosteroid-associated side effects such as   osteoporosis and diabetes, as well as for relapses and flare-ups, is key to chronic management.
Nyeri muskuloskeletal pada leher pekerja dengan posisi pekerjaan yang statis Samara, Diana
Universa Medicina Vol 26, No 3 (2007)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2007.v26.137-142

Abstract

Nyeri leher pada pekerja pada umumnya lebih sering disebabkan oleh gangguan muskuloskletal di mana terjadi ketegangan dan peregangan otot dan ligamentum sekitar leher. Sebuah studi menunjukkan prevalensi nyeri muskuloskeletal pada leher di masyarakat selama satu tahun besarnya 40% dan prevalensi ini lebih tinggi pada wanita. Beberapa pekerjaan yang dapat memicu terjadinya nyeri leher antara lain bekerja dengan komputer dalam waktu yang lama atau bekerja di depan meja dengan posisi membungkuk dalam waktu lama. Mengangkat, mendorong atau membawa barang, penari, dan pengemudi angkutan umum. Gejala-gejala nyeri leher antara lain terasa sakit di daerah leher dan kaku, nyeri otot-otot leher, sakit kepala, dan migraine. Nyeri bisa menjalar ke bahu, lengan, dan tangan disertai keluhan terasa baal atau seperti ditusuk jarum selain itu nyeri juga bisa menjalar ke kepala menyebabkan rasa sakit kepala. Kebanyakan kasus nyeri leher dapat mengalami perbaikan dengan sendirinya. Hal yang penting bagi pekerja yang mengalami nyeri leher adalah modifikasi pekerjaan termasuk manajemen administrasi dan pengaturan ergonomik.
The role of night shift work on blood pressure among healthy female nurses Merijanti, Lie T.; Samara, Diana; Tandean, Reza; Harrianto, Ridwan
Universa Medicina Vol 27, No 2 (2008)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2008.v27.65-71

Abstract

Although hypertension is probably the most common disease on earth, little is known about the association between shift work and hypertension. The aim of this study was to determine the relationship of night shift work and blood pressure among healthy nurses. A cross-sectional study was performed from March to April 2007 among 152 healthy female nurses from one hospital in Central Jakarta. Historical data were obtained from a self-administered detailed questionnaire, while anthropometric and blood pressure variables were measured directly. Shift workers had a significantly lower age (29.2 ± 5.6 years) and shorter job experience (6.9 ± 5.9 years) than day workers (age = 36.5 ± 8.7 years; job experience 15.4 ± 8.4 years). There was a higher prevalence of overweight individuals among shift workers (31/43 = 72.1%) in comparison with day workers (12/43 = 27.9%), even though the difference in prevalence did not reach statistical significance (p=0.121). Analysis of covariance yielded a significant relationship between shift work and systolic blood pressure (p=0.046), even after taking into account age and job experience. Systolic blood pressure was significantly influenced by shift working, while diastolic blood pressure was not (p=0.283). Working in the hospital on a 24-hour shift leads to abnormally high systolic blood pressure in female nurses, thus suggesting that this type of work may be a risk factor for cardiovascular disease.
Musculoskeletal pain and posture decrease step length in young adults Rachmawati, Maria Regina; Samara, Diana; Tjhin, Purnamawati; Wartono, Magdalena; Bastian, Yefta
Universa Medicina Vol 28, No 2 (2009)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2009.v28.92-99

Abstract

Pain of the musculoskeletal system, especially low back pain, is one of the most frequent problems with a high risk of disability. The aim of this research study was to determine the existence of an association between low back pain on one hand,  posture and step length on the other. This cross-sectional study was conducted on 77 healthy young adult subjects. Step length was measured with the Biodex Gait Trainer 2 (230 VAC). The study results indicate that 62.3% of the young adult subjects had suffered from low back pain. There was no significant association between gender and pain. In male subjects no significant association was found between pain on one hand and mean difference in step length and posture on the other. However, in female subjects with abnormal posture, there was a highly significant difference in left step length between subjects with back pain and those without (p=0.007).  The results of a multiple regression analysis indicate that posture has the greatest influence on left step length (B=4.135; 95% Confidence Interval 0.292-7.977). It is recommended that in the examination of low back pain an assessment be made of posture, step length and difference in step lengths.
Gastrointestinal symptoms and sleep disturbance in female nurses Samara, Diana
Universa Medicina Vol 28, No 2 (2009)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2009.v28.100-105

Abstract

Sleep disturbance is a common symptom in the general population. An association between sleep disturbances and functional gastrointestinal (GI) disorders has been reported by several investigators. GI symptoms are more common among people with sleep disturbance in female nurses. To explore this issue further, a study using a cross sectional design was conducted to determine whether unexplained GI symptoms are more common in female nurses with self-reported sleep disturbance. This study was conducted from February through April 2007 in Hospital X in Central Jakarta. A total of 152 female nurses participated in this study. A questionnaire consisting mainly of items concerning sleep disturbance was distributed to the subjects. Significant associations were observed between gastrointestinal symptoms such as anorexia and constipation and sleep disturbance. Constipation was significantly more common in female nurses with sleep disturbance (prevalence ratio=6.1;95% C.I. 1.76 – 20.56), but the association between shift work and sleep disturbance was not statistically significant (prevalence ratio=1.67;95% C.I. 0.53-5.24). Both constipation and anorexia are more prevalent in female nurses with self-reported sleep disturbance. Further research to understand the associations between GI symptoms and sleep disturbance is warranted.
Cullin 1 is not associated with late-onset preeclampsia Samara, Tjam Diana; Liem, Isabella Kurnia; Prijanti, Ani Retno; Andrijono, Andrijono
Universa Medicina Vol 38, No 1 (2019)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (653.458 KB) | DOI: 10.18051/UnivMed.2019.v38.4-9

Abstract

BackgroundLate-onset preeclampsia (PE) is preeclampsia occurring after 34 weeks of gestational age or later.  Cullin 1 (CUL1), a proangiogenic protein, is expressed in the placenta, where an imbalance between proangiogenic and antiangiogenic proteins during gestation can cause disturbance of trophoblast invasion. This defect results in vascular ischemia that may produce preeclampsia. The objective of this study was to determine the correlation between CUL1 as proangiogenic factor and late-onset preeclampsia. MethodsThis study was of analytical observational cross-sectional design and involved 44 preeclampsia patients with ³34 weeks of gestational age (late-onset PE). The CUL1 level in the subjects’ sera, taken before they gave birth, and in homogenates of their placenta, obtained per vaginam or by cesarean section, were examined by the ELISA technique.  Statistical analysis was performed with the Spearman correlation test with significant p value of <0.05.ResultsMedian maternal age was 31 years and median gestational age was 37 weeks.  Median serum CUL1 was 41.78 pg/mL and median placental homogenate CUL1 was 32.24 pg per milligram of total placental tissue protein. There was no significant correlation between serum CUL1 level and late-onset preeclampsia (r=-0.281; p=0.065). There was also no significant correlation between placental CUL1 level and late-onset preeclampsia (r=-0.166; p=0.281).ConclusionSerum CUL1 and placental CUL1 were not correlated with late-onset preeclampsia. However, this study indicated that low serum CUL1 tends to prolong gestational age in preeclampsia.
Comparison of matrix metalloproteinase-9 and E-cadherin expression in early- and late-onset preeclampsia Samara, Tjam Diana; Wibowo, Heri; Liem, Isabella Kurnia; Prijanti, Ani Retno; Andrijono, Andrijono
Universa Medicina Vol. 40 No. 3 (2021)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2021.v40.200-206

Abstract

BACKGROUNDPreeclampsia (PE) is one of the most common pregnancy complications worldwide. Turnover of villous trophoblast is affected by impaired placental perfusion in preeclampsia. Among the various factors that influence pro and antiangiogenic factors in trophoblast invasion of PE are E-cadherin and matrix metalloproteinase-9 (MMP-9). The current classification scheme differentiates PE into two variants early-onset (EO) and late-onset (LO) PE. The aim of this study was to compare MMP-9 and E-cadherin expression between early- (EO) and late-onset (LO) PE. METHODSThis study used a cross-sectional design involving 26 women with gestational age <34 weeks (EO) and 38 women with gestational age ≥34 weeks (LO) from PE patients. Placentas born to preeclamptic mothers were taken in the form of small pieces of the maternal side to measure the levels of MMP-9 and E-cadherin by the ELISA method. Statistical analysis was assessed using the Mann Whitney and independent t-test with a significant p value <0.05. RESULTSSemiquantitative proteinuria levels were significantly higher in EO-PE group compared to LO-PE group (p=0.000). Mean E-cadherin levels were significant lower in the EO-PE group (125.94 ± 54.22 pg/mg) compared to LO-PE group (157.95 ± 54.12 pg/mg) (p=0.024). However, there was no significance difference in median MMP-9 levels between EO-PE group and LO-PE group (p=0.376). CONCLUSIONThis study demonstrate that E-cadherin had lower levels in preeclampsia patients who gave birth <34 weeks. This study indicated that lower levels of e-cadherin can lead to early delivery in preeclampsia patients.
Co-Authors Adrianus Kosasih Alvin M. Ridwan Amirah, Najah Andrijono Andrijono Ani Retno Prijanti Anindra Novita Wulandari Briliant, Permaisonya Danardono, Anindya Diptapratita Dewandhana, Aurelius Ariel Dian Mediana, Dian Dietha Kusumaningrum Dina Rahmayanti Emanuela, Febrina Hairunisa, Nany Haryo Ganeca Widyatama Joice Viladelvia Kalumpiu, Joice Viladelvia KARTINI Kurniasari Kurniasari Kurniasari Kurniasari Kusumaputra, Muhammad Faisal Lenny Setiawati Lestari, Ade Dwi Lie T Merijanti, Lie T Lie T. Merijanti Lie T. Merijanti, Lie T. Liem, Isabella Kurnia Limbong, Herdima Meinardo Luh Putu Ratna Sundari Magdalena Wartono Maharani, Astrid Winesti Maria Regina Rachmawati, Maria Regina ML Edy Parwanto Muflih, Raihan Nany Hairunisa Nany Hairunnisa Noviyanti Noviyanti Nuryani Sidarta, Nuryani Nuryani Sidharta Permasisonya Brilliant Purnamawati Tjhin Purnamawati Tjhin, Purnamawati Rachma, Alya Karunia Ramadhina, Azzahra Putri Reza Tandean Ridwan Harrianto Ridwan Harrianto, Ridwan Ridwan, Alvin Mohamad Riharsono, Galih Chandra Riskita, Fira Salsabila Ayu Widyasyifa Simon, Monica Laurencia Sophian, Azzellia Danivaleiszhka Sutanto, Hans Utama Wulandari, Anindra Novita Yefta Bastian, Yefta Zahrotusyifa, Laila