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All Journal E-Jurnal Medika Udayana Jurnal Penyakit Dalam Indonesia
Handayani, Putu Novi
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Health Professions Medicine & Pharmacology

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Atherogenic Index of Plasma is Correlated with Prolonged Length of Stay in COVID-19 Patients with Type 2 Diabetes Mellitus in RSUP Sanglah Denpasar Sastrawan, I Gede Gita; Upadhana, Putu Satyakumara; Handayani, Putu Novi; Laela, Tika Rizki Nur; Dewi, Kadek Aprilia Sukma; Wiguna, I Nyoman Bayu Andika; Trisna, Cindy Gracia; Putri, Komang Anjani; Agrasidi, Komang Adya Data; Sudarmika, Putu
Jurnal Penyakit Dalam Indonesia Vol. 9, No. 2
Publisher : UI Scholars Hub

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Abstract

Introduction. Atherogenic index of plasma (AIP) is a logarithmic calculation of the ratio of triglycerides to HDL cholesterol as a marker of lipid profile abnormalities. In COVID-19 patients with comorbid type 2 diabetes mellitus (T2DM), higher AIP tend to worsen the patient conditions. This study aims to assess the correlation between AIP and length of stay (LOS) in COVID-19 patients with T2DM.Methods. An analytical observational study with a cross-sectional approach was conducted among COVID-19 patients with comorbid T2DM. Data were collected from online medical records of confirmed COVID-19 patients with comorbid T2DM who were treated at Sanglah Hospital Denpasar during the period August 1-December 31, 2021. Patients who were <18 years old and did not have lipid profile data during>treatment, were excluded from this study.Results. There were 83 data samples that met the study criteria. The median age of the patients was 64 (23- 91) years, the majority were male (59%; n=49), and 30 patients died during treatment (36.1%). The median LOS for all patients was 10 (1-26) days. Patients with prolonged LOS (≥10 days) had higher triglyceride levels (171.8 vs. 120 mg/dL; p<0.001) and AIP values (0.442 vs. 0.286; p=0.02). There was a strong relationship between AIP and LOS values in COVID-19 patients with T2DM (r=0.632; p<0.001). The AIP value can well-discriminated in prolonged LOS conditions (AUC=0.883; 95%CI 0.792-0.974) with the optimal cut-off value of 0.3045 (sensitivity 75.9% and specificity 83.3%).Conclusion. AIP is correlated with prolonged LOS in COVID-19 patients with T2DM. Holistic management of COVID-19 patients with T2DM is urgently needed, including lipid profile control.
HUBUNGAN SHIFT MALAM TERHADAP PENYAKIT REFLUKS GASTROESOFAGUS PADA PERAWAT DI RUMAH SAKIT UMUM PUSAT SANGLAH Handayani, Putu Novi; Kumbara, Cokorde Istri Yuliandari Krisnawardani; Widiana, I Gde Raka; Merati, Ketut Tuti Parwati
E-Jurnal Medika Udayana Vol 12 No 1 (2023): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2023.V12.i01.P14

Abstract

Gastroesophageal reflux disease is one of the most frequently diagnosed gastrointestinal diseases in the world with a prevalence that continues to increase every year. There are several studies state that night shifts can increase the risk of GERD. One group of workers who often undergo night shift rotation are nurses who work in hospitals. This study aims to determine the correlation between night shift work and gastroesophageal reflux disease among nurses. This study is an analytical study with a cross-sectional design. The data collection technique was carried out by purposive sampling by distributing questionnaires to 161 nurses on duty at Single Hospital which were divided into 85 Inpatient Installation nurses who worked night shifts and 76 Outpatient Nurses who worked morning shifts. This study found a significant correlation between night shift work and gastroesophageal reflux disease (p value = 0.013; Prevalence Ratio = 3; 95% Confidential Interval 1.18-7.84) by the chi square test. Furthermore, by the logistic regression analysis of night shift and GERD, the AOR (Adjusted Odd Ratio) was 3.61 with 95% CI (1.05-12.52) and other variable like age, gender, BMI and fast food consumption habits on GERD did not shown any significant result. There is a significant correlation between night shift work and gastroesophageal reflux disease. Nurses who undergo night shifts have a 3.61 times higher risk of experiencing GERD. Keywords : Night Shift Work, Gastroesophageal Reflux Disease, Nurse
Co-Authors Agrasidi, Komang Adya Data Dewi, Kadek Aprilia Sukma I Gde Raka Widiana Ketut Tuti Parwati Merati Kumbara, Cokorde Istri Yuliandari Krisnawardani Laela, Tika Rizki Nur Putri, Komang Anjani Sastrawan, I Gede Gita Sudarmika, Putu Trisna, Cindy Gracia Upadhana, Putu Satyakumara Wiguna, I Nyoman Bayu Andika