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All Journal The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal Penyakit Dalam Indonesia
Puspadina, Shafira
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Medicine & Pharmacology

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Effectivity of Opioid Rotation Compared to Opioid Combination for Cancer Pain: An Evidence Case Report Faisal, Edward; Puspadina, Shafira; Puranto, Rudi; Shatri, Hamzah
Jurnal Penyakit Dalam Indonesia Vol. 9, No. 2
Publisher : UI Scholars Hub

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Abstract

Pain is the main symptom in cancer patients that needs to be addressed immediately because it can reduce the quality of life. Concern or the ineffectiveness of using one type of opioid makes it necessary for clinicians to understand how to rotate opioids. Therefore, this evidence-based case report was conducted to identify the effectiveness of opioid rotation and combined opioids for the cancer pain management through a literature search on three databases. Literature searching was performed by using Pubmed, Cochrane library, and EBSCO according to clinical inquiries. Of the 24 studies obtained, only one study met the criteria and was then critically assessed. The study found that pain score in both opioid rotation group (fentanyl transdermal) and combined opioids group (oral oxycodone and fentanyl transdermal) was decreased from 2.9 to 2.0 (p=0.22) and 3.0 to 1.8 (p<0.06), respectively. In addition, therapeutic success was achieved in 11 patients in the opioid rotation group and 12 patients in the combined opioids group (p=0.98). Based on the study, it can be concluded that opioid rotation is as effective as combined opioids in managing pain in cancer patients.
Diagnostic Approach and Management of Solid Pancreatic Mass Puspadina, Shafira; Simadibrata, Marcellus
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 23, No 3 (2022): VOLUME 23, NUMBER 3, December 2022
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2332022234-239

Abstract

The pancreas is a complex organ in which a suspicious lesion can appear which can be benign or malignant. Clinical manifestation can guide the clinician to choose the appropriate tests such as autoimmune tests, tumor markers, imaging with ultrasonography (USG), computerized tomography (CT), magnetic resonance imaging (MRI), or magnetic resonance cholangiopancreatography (MRCP), and endoscopic or surgical tissue biopsy. Pancreatic nodule therapy is tailored to the nature of the nodule, etiology-appropriate therapy for benign nodules or surgery, chemotherapy, and radiotherapy for cancerous nodules. Knowledge of the diagnostic approach of pancreatic solid mass is important for clinician to make prompt and accurate treatment for patients and to prevent unnecessary examination or intervention.
Co-Authors E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Faisal, Edward Marcellus Simadibrata Puranto, Rudi