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All Journal Narra J The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal Penyakit Dalam Indonesia Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Faisal, Edward
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Effect of Advance Care Planning on Heart Failure Patients: An Evidence Based Case Report Shatri, Hamzah; Nurfitria, Nandika; Sinulingga, Dika; Irvianita, Vinandia; Faisal, Edward; Putranto, Rudi; Martina, Diah
Jurnal Penyakit Dalam Indonesia Vol. 9, No. 4
Publisher : UI Scholars Hub

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Abstract

Despite the advances in medical therapy, heart failure remains a disease that requires attention due to the course of the illness; it can lead to unpredictable, progressive, and fatal conditions. Existing therapy aims to improve the condition and prevent disease progression, with a balanced secondary therapy for various conditions that can trigger acute decompensated heart failure. Advances in technology and therapy may increase the prevalence of patients with heart failure, including prolonging the refractory phase of the disease. There are recommendations for advance care planning to support patient therapy and improve the quality of life of patients with heart failure. This evidence-based case report aims to investigate the benefits of advance care planning in heart failure patients. A heart failure patient is referred to the palliative care team for advance care planning. Literature searches were conducted on ProQuest, PubMed, Scopus, and Cochrane according to the clinical questions. The studies were selected based on the inclusion and exclusion criteria, then a critical review was conducted. One study showed significant results regarding the effectiveness of advance care planning on the quality of life of heart failure patients. Another study showed a significant improvement in depression among patients engaged in advance care planning. However, it showed no difference in the quality of life compared to usual care because the sample size was relatively small, and the quality of evidence was low. Therefore, it can be concluded that advance care planning can improve heart failure patients’ psychological symptoms and quality of life.
Effectivity of Opioid Rotation Compared to Opioid Combination for Cancer Pain: An Evidence Case Report Faisal, Edward; Puspadina, Shafira; Puranto, Rudi; Shatri, Hamzah
Jurnal Penyakit Dalam Indonesia Vol. 9, No. 2
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Pain is the main symptom in cancer patients that needs to be addressed immediately because it can reduce the quality of life. Concern or the ineffectiveness of using one type of opioid makes it necessary for clinicians to understand how to rotate opioids. Therefore, this evidence-based case report was conducted to identify the effectiveness of opioid rotation and combined opioids for the cancer pain management through a literature search on three databases. Literature searching was performed by using Pubmed, Cochrane library, and EBSCO according to clinical inquiries. Of the 24 studies obtained, only one study met the criteria and was then critically assessed. The study found that pain score in both opioid rotation group (fentanyl transdermal) and combined opioids group (oral oxycodone and fentanyl transdermal) was decreased from 2.9 to 2.0 (p=0.22) and 3.0 to 1.8 (p<0.06), respectively. In addition, therapeutic success was achieved in 11 patients in the opioid rotation group and 12 patients in the combined opioids group (p=0.98). Based on the study, it can be concluded that opioid rotation is as effective as combined opioids in managing pain in cancer patients.
Advanced Directives in Palliative Care Shatri, Hamzah; Faisal, Edward; Putranto, Rudi; Sampurna, Budi
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 2
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Initially palliative care is emphasized at the end of life, but the right thing is to begin identifying palliative care needs when the disease is diagnosed. Palliative care is the treatment needed to improve the quality of life of patients and their families that suffering from life threatening and progressive disease such as cancer, non-cancer diseases, and HIV/AIDS (human immunodeficiency virus/acquired immunodeficiency syndrome). Palliative care decision must be in place from the beginning of treatment, so the patient’s preferences are met. The goals of this care are to reduce physical, social, psychological, and spiritual suffers. Further treatment plan is based on discussion between patient, family, and health care worker. The final result is identification and decision that can be written in advanced directives.
Depression in Heart Failure: Psychosomatic Approachv Putranto, Rudi; Shatri, Hamzah; Wijaya, Ika Prasetya; Faisal, Edward
Jurnal Penyakit Dalam Indonesia Vol. 8, No. 3
Publisher : UI Scholars Hub

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Depression is a common condition in heart failure (HF) and is considered a risk factor for cardiovascular disease. Depression disorder in patients with heart disease paradigmatically defines a psychosomatic-somatopsychic challenge to any health delivery. However, despite the devastating effects of depression, it is often underdiagnosed and receives little attention in heart failure patients. This review provides an extensive overview of HF regarding epidemiology, disease pathophysiology, diagnosis, and management from the latest literature. Based on the literature review, the prevalence of depression in heart failure in Indonesian patients was 5.3-42%. Psychological stress experienced by people suffering from depression can cause dysregulation in the sympathetic nervous system and hypothalamic–pituitary–adrenal (HPA) axis. This mechanism, in turn, has some deleterious downstream effects, including the development of hypertension, left ventricular hypertrophy, coronary vasoconstriction, endothelial dysfunction, platelet activation, and the production of pro-inflammatory cytokines. The Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5), published by the American Psychiatric Association, is used to diagnose depression in patients with HF. Meanwhile, the Patient Health Questionnaire (PHQ)-2 and PHQ-9 are commonly used as screening tools for depression in patients with HF. The Biopsychosocial-spiritual model as a psychosomatic approach have might reduce or prevent depression and thus improve quality of life and other outcomes. Evidence reveals that both psychotherapeutic treatment (e.g., cognitivebehavioral therapy) and pharmacologic treatment (e.g., use of the selective serotonin reuptake inhibitor sertraline) are safe and effective in managing depression in patients with cardiovascular disease. In conclusion, the review of articles in this paper shows that there is a high prevalence of depression in heart failure, but it is often not recognized by doctors, there is a relationship between psychosomatic, and heart failure, non-pharmacological interventions such as psychotherapy and pharmacological therapy have benefits. Future research is needed to create evidence-based evaluations and treatment algorithms tailored to the specific needs of the target population.
Pain Management in Advanced Hepatocellular Carcinoma:A Case Study Fitrianti, Fita; Shatri, Hamzah; Faisal, Edward; Putranto, Rud; Agung, Ratih Arianita; Nainggolan, Leonard; Kalista, Kemal Fariz; Irawan, Cophiadi
Jurnal Penyakit Dalam Indonesia Vol. 9, No. 1
Publisher : UI Scholars Hub

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Hepatocelullar carcinoma (HCC), the most common primary liver malignancy is the fifth most common cancer and the third most frequent cause of cancer related death globally. Pain comprises one the most common symptoms of HCC and may have severely negative effects on patient’s quality life. Furthermore, patients with HCC often presented with a cirrochis,so to control pain in this patient poses a clinical challenge. This case report discuss about a young 26-years-old male patient who presented with a four-month history of right upper quadrant abdominal pain and weight loss. HbsAg positive and serum alpha-fetoprotein level was high. Computed tomography (CT) and liver biopsy confirmed the presence of primary hepatocellular carcinoma.,with lung metastatic from the radiologic x-ray. Patient came with a loss of consciousness due to hypoglicemia. During hospitalization, patient complaint of abdominal pain and was given morphine intermediate release (MIR) to control the pain. By administering measurable and well-controlled opioids, the patient’s suffering can be reduced, thus improving the patient’s quality of life
Depresi pada Populasi Lanjut Usia yang Menjalani Hemodialisis Faisal, Edward
Jurnal Penyakit Dalam Indonesia Vol. 8, No. 4
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Menurut laporan tahunan European Renal Association–European Dialysis and Transplant Association (ERA-EDTA), pasien yang menjalani transplantasi ginjal dari tahun 2014 sampai 2018 memiliki kesempatan hidup hanya setengah dari usia dengan sisa fungsi ginjal yang ditransplantasikan, sedangkan untuk pasien yang dilakukan hemodialisis (HD) adalah 70% lebih pendek.
Etika Publikasi di Bidang Kedokteran Jasirwan, Chyntia Olivia Murine; Faisal, Edward; Yunihastuti, Evy
Jurnal Penyakit Dalam Indonesia Vol. 11, No. 1
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Publikasi ilmiah merupakan penjelasan sistematis mengenai hipotesis, bukti, dan kesimpulan dari sebuah penelitian yang dimaksudkan untuk mengedukasi masyarakat. Publikasi merupakan tujuan utama dari penelitian, dan peer-review dilakukan untuk memverifikasi temuan dan meningkatkan kepercayaan penulis untuk evaluasi penelitian yang dipublikasi. Publikasi merupakan salah satu persyaratan khusus dalam suatu institusi akademik dan dapat mendukung promosi ke jabatan akademis. Publikasi (nasional dan internasional) telah menjadi norma yang dapat dikatakan wajib dalam dunia pendidikan. Berbagai pelanggaran etika banyak terjadi dan kita temukan, seperti plagiarisme, tata bahasa yang tidak pantas, dan praktik pengelolaan data yang meragukan. Kurangnya pemahaman tentang etika penelitian seringkali menjadi akar dari masalah ini.
Selective Serotonin Reuptake Inhibitors and Risk of Gastrointesinal Bleeding In Dyspepsia: An Evidence-Based Case Report Shatri, Hamzah; Zulkifly, Steven; Putranto, Rudi; Makmun, Dadang; Fauzi, Achmad; Maulahela, Hasan; Faisal, Edward; Irvianita, Vinandia; Ardani, Yanuar
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 24, No 2 (2023): VOLUME 24, NUMBER 2, August, 2023
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2422023182-191

Abstract

Aim: This evidence-based case report aims to provide the latest evidence about the risk of gastrointesinal (GI) bleeding in selective serotonin reuptake inhibitor (SSRI) users with dyspepsia.Method: The literature search was conducted in four major electronic databases (PubMed, Cochrane, Scopus, ProQuest). The selected articles were sorted through screening abstract based on the inclusion and exclusion criteria. Critical appraisal was performed by using validated critical appraisal tool.Results: Of 247 records from extensive literature searching, three eligible studies (one randomized clinical trial and two cohort studies) were obtained to answer the clinical question. All studies showed SSRIs did not increase the risk of GI bleeding in patients with functional dyspepsia and peptic ulcer. However, the adverse event of SSRIs might be under-reported.Conclusion: According to the evidence, the risk of GI bleeding in SSRIs users with dyspepsia is still unclear. Larger size of sample of controlled trial study is recommended to be conducted to calculate the precise risk of GI bleeding in SSRI users with dyspepsia.
Validity and reliability testing of the Shatri Sinulingga psychosomatic test (SSPT) questionnaire as a screening instrument for psychosomatic disorders in Indonesia Shatri, Hamzah; Sinulingga, Dika I.; Faisal, Edward; Irvianita, Vinandia; Putranto, Rudi; Ardani, Yanuar; Erlita, Diana; Jeger, Dian P.; Browijoyo, Isa A.
Narra J Vol. 4 No. 3 (2024): December 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i3.1373

Abstract

The incidence of psychosomatic disorders is increasing in Indonesia, and therefore screening instruments that are culturally appropriate for the Indonesian population are needed. The aim of this study was to assess the validity and reliability of the Shatri Sinulingga psychosomatic test (SSPT) questionnaire as a screening instrument for psychosomatic disorders in Indonesia. An analytic descriptive cross-sectional study divided into two stages (questionnaire formulation and distribution through the Psikosom.id application) was conducted in 2023. The validity test was carried out using the product moment technique, and Cronbach's alpha assessment was carried out to evaluate the reliability of the questionnaire. A total of 372 participants were included, with a mean age of 39.24 years old. The SSPT questionnaire scores had strong correlations with the scores of hospital anxiety and depression scale (HADS) (r=0.668; p<0.001) and the Symptom Checklist-90 (SCL-90) (r=0.674; p<0.001); and moderately correlated with the score of fatigue severity scale (FSS) (r=0.505; p<0.001) and Pittsburgh Sleep Quality Index (PSQI) (r=0.492; p<0.001). The correlation coefficient (r) value of each SSPT question ranged from 0.389–0.726, and all r higher than r table with an overall Cronbach’s alpha of 0.744. The SSPT questionnaire's strong predictive performance: had a sensitivity of 75.6% and specificity of 71.4% with an area under the curve (AUC) of 81% (95%CI: 76.6–85.4%; p<0.001) to HADS; sensitivity of 80% and specificity of 58.6% with an AUC of 75.1% (95%CI: 70–80.2%; p<0.001) to FSS; sensitivity of 64% and specificity of 67.5% with an AUC of 71.2% (95%CI:  65.4–77%; p<0.001) to PSQI; and had sensitivity of 78% and specificity of 67.4% with an AUC of 80.9% (95%CI:  76.6–85.3%; p<0.001) to SCL-90. The study highlights that the SSPT questionnaire is valid and reliable to be used as a screening instrument for psychosomatic disorders in Indonesia.
Efek Hipnoterapi untuk Meningkatkan Kualitas Hidup pada Pasien Penyakit Ginjal Kronik: Suatu Laporan Kasus Berbasis Bukti Chairani, Aisha Putri; Putranto, Rudi; Shatri, Hamzah; Marbun, Maruhum Bonar Hasiholan; Faisal, Edward; Irvianita, Vinandia; Martina, Diah
Jurnal Penyakit Dalam Indonesia
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Chronic Kidney Disease (CKD) is a condition of kidney damage with a decrease in glomerulus filtration rate of 60 ml/min/1.73 m3 for a duration of more than three months. CKD is closely related to the patient’s quality of life because the patient must carry out various lifestyle restrictions to slow the progression of kidney damage. Lifestyle restrictions often cause problems in the psychosocial field that increase the severity of symptoms and decrease kidney function faster. This evidence-based case review was compiled to determine the effectiveness of hypnotherapy in improving the quality of life of CKD patients. Literature searches were conducted in four databases, namely PubMed, Cochrane, EMBASE, and Scopus. There are three literatures that fit the eligibility criteria. The critical review was conducted using guidelines created by the Centre for Evidence-Based Medicine, University of Oxford. Hypnotherapy consistently shows improved quality of life in the form of decreased symptoms of anxiety, depression, drowsiness, fatigue, and improved social functioning and relationships with family. Hypnotherapy can be considered a complementary therapy in the management of CKD patients with minimal side effects by considering the patient’s accessibility and preferences.
Co-Authors Achmad Fauzi Agung, Ratih Arianita Ardani, Yanuar Browijoyo, Isa A. Budi Sampurna Chairani, Aisha Putri Dadang Makmun Diah Martina, Diah E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Erlita, Diana Evy Yunihastuti Fitrianti, Fita Hasan Maulahela, Hasan Ika Prasetya Wijaya Irawan, Cophiadi Irvianita, Vinandia Jasirwan, Chyntia Olivia Murine Jeger, Dian P. Kemal Fariz Kalista, Kemal Fariz Kosasih, Kartika Anastasia Leonard Nainggolan Marbun, Maruhum Bonar Hasiholan Nurfitria, Nandika Poespitasari, Vinandya Irvianita Puranto, Rudi Puspadina, Shafira Putranto, Rud Raniah, Nida Rudi Putranto Sihwastuti, Sihwastuti Sinulingga, Dika Sinulingga, Dika I. Sumariyono Sumariyono Wulyo Rajabto Zulkifly, Steven