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All Journal Jurnal Ilmiah Farmasi Jurnal Penelitian Sains Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Jurnal Kesehatan Saelmakers PERDANA (JKSP) Jurnal Ilmiah Bakti Farmasi
Sari Meisyayati, Sari
STIFI Bhakti Pertiwi Palembang
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health

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Efek Analgetik Kombinasi Infusa Daun Sirih (Piper betle L.) dan Infusa Daun Kemangi (Ocimum sanctum L.) terhadap Mencit Putih Jantan Galur Swiss Webster Sari Meisyayati; Jelin Wulandari; Erjon
Jurnal Ilmiah Bakti Farmasi Vol 4 No 2 (2019): Jurnal Ilmiah Bakti Farmasi
Publisher : Lembaga Penelitian & Pengabdian Kepada Masyarakat (LPPM) STIFI Bhakti Pertiwi Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (342.861 KB)

Abstract

Telah dilakukan penelitian uji efek analgetik kombinasi daun sirih (Piper betle L.) dan daun kemangi (Ocimum sanctum L.) terhadap mencit putih jantan yang diinduksi dengan asam asetat 1% v/v secara intraperitoneal. Mencit putih jantan galur Swiss Webster umur 2-3 bulan dengan berat 20-30 g dibagi menjadi 6 kelompok perlakuan. kelompok I sebagai kontrol negatif diberi ssediaan aquadest, kelompok II sebagai kontrol positif diberi sediaan suspensi aspirin, kelompok III diberi sediaan infusa daun kemangi 20%b/v, kelompok IV diberi sediaan daun sirih 40%b/v, kelompok V diberi sediaan kombinasi infusa daun kemangi 10%b/v dan infusa daun sirih 20%b/v, kelompok VI diberi sediaan kombinasi infusa daun kemangi 5%b/v dan infusa daun sirih 10%b/v yang diberikan secara peroral. Pengamatan dilakukan setiap 5 menit selama 1 jam setelah diinduksi dengan asam asetat 1% v/v secara intraperitoneal. Data geliat kumulatif rata-rata dihitung % proteksi. Kemudian data jumlah respon geliat kumulatif yang diperoleh dianalisis dengan uji ANOVA. Hasil penelitian menunjukan bahwa sediaan infusa memiliki efek analgetik terhadap mencit putih jantan, dan adanya efek yang aditif dari kombinasi infusa daun kemangi 10%b/v dan infusa daun sirih 20%b/v.
Activity Antifungi Of Oil Atsiri Sereh Wangi (Cymbopogon Nardus (L) Rendle). Nilda Lely; Hetty Sulastri; Sari Meisyayati
Jurnal Kesehatan Saelmakers PERDANA (JKSP) Vol. 1 No. 1 (2018): Jurnal Kesehatan Saelmakers PERDANA
Publisher : Fakultas Ilmu Kesehatan Universitas Katolik Musi Charitas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32524/jksp.v1i1.100

Abstract

Citronella fragrance is one of the many plants in Indonesia. Citronella fragrance is widely used by Indonesian people as a spice dish and has traditionally been used for various treatments. Citronella fragrance contains essential oils that have the potential to have anti- fungal effects and have traditionally been used for the treatment of skin diseases. Isolation of citronella essential oil with the method of vapor distillation. The tested fungi are opportunistic fungi that often infect human skin. In testing the antifungal activity of the citronella essential oil (Cymbopogonnardus (L.) Rendle) against the fungal causing skin infection. The research was done by using agar diffusion method and using the density disc as the diffusion medium against A research of antifungal?s activity of essential oil of citronella (Cymbopogon nardus (L.) Rendle ) to fungus that cause disease in humans has been done. This research used agar diffusion method to the fungus test Tricophyton rubrum, Tricophyton mentagrophytes and Candida albicans. The concentration that used 1%, 0,5%, 0,25% and 0,1%. The results showed that in concentration 1% essential oil of citronella (Cymbopogon nardus ( L.)Rendle) has the highest activity with Candida albicans with an average of inhibition diameter was 19,4mm ± 0,15. In 0,1% concentration of essential oil of citronella (Cymbopogon nardus (L.) Rendle) does not have antifungal?s activity to Tricophyton mentagrophytes that without inhibition diameter around the paper discs. Meanwhile, in concentration 0,1%, the essential oil of citronella (Cymbopogon nardus (L.) Rendle) still have antifungal?s activity to Tricophyton rubrum and Candida albicans with an average of inhibition diameter 7,4 mm ± 0,35 dan 8,5 mm ± 0,15.
Co-Authors Ade Arinia Rasyad Agnes Leorina Ahmad Fatoni Aisah Aisah Alex Ferianto Ayu Lestari Budi Untari David Darwis Erjon Erjon Erjon, . Frelis Setya Nanda Geby Patriani Hetty Sulastri Jelin Wulandari Josafin Immanuel Jouliyano Dwiputri Lidia Lidia Lidia Lidia, Lidia Marisyah Dewiwaty, Marisyah Nilda Lely Petrus Chanel Aprianto Ramona Rizki Wahyudi Sulastri, Hetty Sulastri, Hetty Wahyudi Apriyanto Yenni Sri Wahyuni Yopi Rikmasari, Yopi