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All Journal JURNAL BIOLOGI PAPUA
Corry N. Mahama
PDIB Fakultas Kedokteran Universitas Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Environmental Science Materials Science & Nanotechnology

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Analisis Polimorfisme Gen dan Aplikasinya Dalam Klinik Corry N. Mahama; Dwi A. Suryandari
Jurnal Biologi Papua Vol 15, No 1 (2023)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31957/jbp.2479

Abstract

Gene polymorphism refers to a variation in DNA sequence that occurs in a population with a frequency of 1% or higher. Polymorphism may be a variation in single nucleotide (SNP) or a variation in some repetitive DNA sequences (length polymorphism). Several methods can be used to analyze polymorphism, included Polymerase Chain Reaction (PCR), DNA sequencing from the conventional method to more sophisticated method such as Next Generation Sequencing (NGS), fluorescence in situ hybridization, comparative genomic hybridization, and DNA microarrays. Recently, more studies have been carried out to find the relationship between polymorphism and disease severity or prognosis, response to various drugs, susceptibility to environtmental factors such as toxins, susceptibility to infections and cancers.Key words: DNA; gene polymorphism; PCR; clinic.
Co-Authors Dwi A. Suryandari