Magfira Satya Apada
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Activity Test of bitter melon Leaf Infusion (Momordica charantia) as an anthelmintic toward Ascaridia galli worms in vitro Jamaluddin, Abdul Wahid; Andi Muhammad Taufan; Adriyani Ris; Magfira Satya Apada
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 7, No 1, JANUARY 2023
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jrvi.v7i1.25154

Abstract

Ascaridia galli is a gastrointestinal parasite in poultry which can cause weight loss, slow growth and affect egg production. Chickens that are infected can cause damage to the integrity of the intestinal villi to severe inflammation of the intestinal mucosa. Bitter melon leaf (Momordica charantia) is known to have an anthelmintic effect which can be used as an alternative in the treatment of worms disease. The purpose of the research is to determine activity of bitter melon leaf infusion toward Ascaridia galli conducted in vitro. In the research, it uses 72 Ascaridia galli that divided into 4 groups consisting of positive control group (Levamid), negative control group (Aquadest), and 2 treatment group with 10%, and 20% bitter melon leaf infusion concentration, respectively. Each group replicated three times. The worms were immersed in the test solution and observations were performed every 15 minutes and counted the number of worms that died. The results showed that pare leaf infusion with concentrations of 10% and 20% had an anthelmintic effect but was no better than Levamid as a positive control.
The Description Blood Profile In Hemorrhagic Shock Rabbits Treated With Ringer's Lactate and Gelatin Resuscitation monica, waode santa; Magfira Satya Apada; Muhammad Nur Amir; Nurul Sholihah Budiyana; Anggini Putri Husada
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 7, No 2, JULY 2023
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jrvi.v7i2.24109

Abstract

Background: Hemorrhagic shock is a condition that causes rapid and significant loss of intravascular blood volume, further leading to hemodynamic instability, decreased oxygen delivery, decreased tissue perfusion, cellular hypoxia, organ damage, and death. In conditions of hemorrhagic shock, measures are needed to prevent death in both humans and animals, one of which is by providing fluid therapy such as lactate ringer and gelatin. The purpose of the study: to see the effect of resuscitation of lactate and gelatin ringer fluid from the aspect of animal blood profile includes total erythrocytes, hematocrit (HCT) and hemoglobin (Hb). Research method: the sample in the study using male rabbits as many as 12 rabbits was divided into four groups: The negative control group (NC) was a healthy group without bleeding, the positive control group (PC) was the group given the bleeding treatment, the treatment group 1 (TG1) was the bleeding group and was treated with lactate ringer, and the treatment group 2 (TG2) was the bleeding group and treated a combination of lactate ringer and gelatin. Rabbits are bleeding with a presentation of 30% until they reach a state of hemorrhagic shock then shock is maintained for 45 minutes before resuscitation of fluid and for 60 minutes given fluid resuscitation. The results of the study: showed that the NC, PC, TG1, and TG2 groups showed a decrease in HCT values of 1.6%, 11.3%, 9% and 12%, respectively. Meanwhile, Hb values in rabbits decreased on average to 22 gr / dl, 13 gr / dl, 24.4 gr / dl and 20.9 gr / dl. Meanwhile, the total erythrocyte value showed a decrease in the average value reaching 2.48 x 106 / μL, 3.16 x 106 / μL, 4.2 x 106 / μL, and 3.9 x 106 / μL. The decline that occurs in the NC group is normal because the decrease that occurs is influenced by blood sampling, but in the PC, TG1, and TG2 groups are affected by the bleeding process. Based on the results of the study, it shows an increase in the indicators of Hb and Total Erythrocytes, this shows that giving fluid resuscitation to rabbits who experience hemorrhagic shock gives better results to the blood profile picture. Background: Hemorrhagic shock is a condition that causes rapid and significant loss of intravascular blood volume, further leading to hemodynamic instability, decreased oxygen delivery, decreased tissue perfusion, cellular hypoxia, organ damage, and death. In conditions of hemorrhagic shock, measures are needed to prevent death in both humans and animals, one of which is by providing fluid therapy such as lactate ringer and gelatin. The purpose of the study: to see the effect of resuscitation of lactate and gelatin ringer fluid from the aspect of animal blood profile includes total erythrocytes, hematocrit (HCT) and hemoglobin (Hb). Research method: the sample in the study using male rabbits as many as 12 rabbits was divided into four groups: The negative control group (NC) was a healthy group without bleeding, the positive control group (PC) was the group given the bleeding treatment, the treatment group 1 (TG1) was the bleeding group and was treated with lactate ringer, and the treatment group 2 (TG2) was the bleeding group and treated a combination of lactate ringer and gelatin. Rabbits are bleeding with a presentation of 30% until they reach a state of hemorrhagic shock then shock is maintained for 45 minutes before resuscitation of fluid and for 60 minutes given fluid resuscitation. The results of the study: showed that the NC, PC, TG1, and TG2 groups showed a decrease in HCT values of 1.6%, 11.3%, 9% and 12%, respectively. Meanwhile, Hb values in rabbits decreased on average to 22 gr / dl, 13 gr / dl, 24.4 gr / dl and 20.9 gr / dl. Meanwhile, the total erythrocyte value showed a decrease in the average value reaching 2.48 x 106 / μL, 3.16 x 106 / μL, 4.2 x 106 / μL, and 3.9 x 106 / μL. The decline that occurs in the NC group is normal because the decrease that occurs is influenced by blood sampling, but in the PC, TG1, and TG2 groups are affected by the bleeding process. Based on the results of the study, it shows an increase in the indicators of Hb and Total Erythrocytes, this shows that giving fluid resuscitation to rabbits who experience hemorrhagic shock gives better results to the blood profile picture.