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All Journal Jurnal Biomedika dan Kesehatan Journal of Urban Health Research
Mikhael Aditya
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Potential Factors related to COVID-19 Vaccine Hesitancy in Indonesia: A Literature Review Kevin Kristian; Anisya Lutfia Andini; Fransiska Eka Putri; Julian; Karina Sylvana; Kenji Sungkhar; Mentari Artanti Jelita; Mikhael Aditya
Journal of Urban Health Research Vol. 1 No. 2 (2023): Journal of Urban Health Research
Publisher : School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/juhr.v1i2.4205

Abstract

Introduction: The pandemic of COVID-19 has become a burden to the world's health system, in which strategic measures are needed, especially vaccination. However, numbers of challenge have been reported regarding the so-called most effective public health intervention, such as vaccine hesitancy. On top of that, WHO has acknowledged vaccine hesitancy in the top list of 10 most dangerous threats to global health. The spectrum related to the reluctance to receive vaccination in society has also occurred in previous infectious diseases management and during the COVID-19 pandemic. This review aimed to identify factors and mechanism related to COVID-19 vaccine hesitancy in Indonesia. Method: This study provided a review of 14 literatures from 2019 to 2021 using ProQuest and Google Scholar discovered through the selected keywords. The SAGE WG model for vaccine hesitancy framework was used as the main reference in identifying and explaining the associated factors of phenomenon. Results: Based on the analysis of framework, determinants related to confidence crucial in affecting the acceptance level of COVID-19 vaccine in the community. In regard to that aspect, various factors within the scope of individual and social influences, vaccine and vaccination-specific issues, as well as contextual influences may well-explained the plausible mechanism that build hesitancy over vaccination. Accordingly, this study found that mistrust and skepticism related to the effectiveness of vaccine, safety concerns, and adverse reactions discouraged people from getting vaccinated. Furthermore, religious matters such as unavailable halal certification, along with poor socioeconomical factors, and misinformation that were spread through the media also prevent people to receive COVID-19 vaccine and risk the development of herd-immunity toward COVID-19 in the community. Conclusions: Various factors were identified regarding the development of vaccine hesitancy in Indonesia. Understanding the plausible factors and mechanism that prevented people to get COVID-19 vaccine are substantial to strategically address the phenomenon and successfully manage the COVID-19 pandemic in Indonesia. Keywords: COVID-19 – Indonesia - vaccine hesitancy – asia – outbreak - prevention
Kesesuaian hasil ultrasonografi dan diagnosis klinis terhadap pemeriksaan histopatologis penderita limfadenitis tuberkulosis regio servikal Mikhael Aditya; Yopi Simargi
Jurnal Biomedika dan Kesehatan Vol 2 No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2019.v2.20-26

Abstract

LATAR BELAKANGLimfadenopati regio servikal merupakan kasus yang sering terjadi sebagai manifestasi berbagai penyakit, termasuk tuberkulosis. Teknik pemeriksaan kelenjar getah bening yang menjadi standar baku adalah histopatologi. Pemeriksaan non-invasif berupa ultrasonografi (USG) dapat menjadi alternatif untuk menegakkan diagnosis tuberkulosis kelenjar getah bening. Oleh karena itu, penelitian dilakukan untuk mengetahui nilai kesesuaian USG sebagai alat diagnosis limfadenitis tuberkulosis, termasuk nilai akurasi, sensitivitas, spesifisitas, nilai duga positif, dan nilai duga negatif dibandingkan dengan standar baku. METODEPenelitian dilakukan secara deskriptif retrospektif dengan teknik pengambilan sampel potong lintang (cross-sectional) menggunakan 100 rekam medis pasien limfadenopati regio servikal di rumah sakit (RS) Atma Jaya, Jakarta. Waktu pemeriksaan ultrasonografi dan histopatologi pada periode Oktober 2015 hingga Oktober 2017. Analisis data dilakukan untuk mengetahui akurasi, sensitivitas, spesifisitas, nilai duga positif, dan nilai duga negatif, serta tingkat kemaknaan hasil ultrasonografi dan diagnosis klinis dalam mendiagnosis tuberkulosis. Analisis data menggunakan uji proporsi sampel dengan tingkat kemaknaan p<0.05. HASILSebanyak 59 pasien (59.0%) terdiagnosis tuberkulosis berdasarkan pemeriksaan histopatologi. Akurasi, sensitivitas, spesifisitas, nilai duga positif, dan nilai duga negatif ultrasonografi berturut-turut sebesar 69.0%; 59.3%; 83.0%; 83.3%; dan 58.6%. Pengujian data menunjukkan perbedaan bermakna hasil ultrasonografi terhadap hasil histopatologi (p=0.0005), sehingga hasil ultrasonografi dianggap belum sesuai secara statistik. KESIMPULANUltrasonografi belum dapat menjadi alternatif pilihan untuk menegakkan diagnosis tuberkulosis secara statistik, namun dapat menjadi alat evaluasi tuberkulosis yang baik. Penelitian lebih lanjut masih perlu dilakukan.
Co-Authors Anisya Lutfia Andini Fransiska Eka Putri Julian Karina Sylvana Kenji Sungkhar Kevin Kristian Mentari Artanti Jelita Yopi Simargi