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All Journal Indonesian Journal of Urology Indian Journal of Forensic Medicine & Toxicology Jurnal Rekonstruksi dan Estetik
Indri Lakhsmi Putri, Indri Lakhsmi
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Health Professions Medicine & Pharmacology Public Health

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Time Recommendation and Alternative Parameters for Severe Maxillofacial Trauma Reconstruction Indri Lakhsmi Putri1, Magda Rosalina Hutagalung1, Ida Bagus Narmada2, David Sontani Perdanakusuma1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3160

Abstract

Background: Severe maxillofacial trauma often associated with other injuries, therefore the delay of reconstruction often occur until the patients are stable. Early reconstruction results a better facial function and appearances. Aim: The aim of this study to give the recommendation and alternative parameters for severe maxillofacial trauma reconstruction. Methods: The method of this study is adult patients with bimaxillary and bilateral maxillofacial trauma were eligible for this study, while pregnant women were excluded. Nine patients with maxillofacial trauma were involved in this study and we measured 15 facial anthropometric and 41 lateral cephalometricon 7, 14, 21 days compared to 3 months post-reconstruction. Results: The result of this study showed reconstruction can be planned 14 days after trauma for lower jaw fracture and 21 days after bimaxillary fracture. Lateral cephalometry was a reliable method to measure facial edema following surgery which combined facial anthropometry with lateral cephalometry using parameters that are not affected by edema. This can be applied as an additional guiding tool in surgical planning for maxillofacial trauma patients especially those with bimaxillary and bilateral fractures. Conclusion: Combination of anthropometric and cephalometric parameters which are not affected by edema can be applied as an additional guiding tool in surgical planning for maxillofacial trauma patients.
THE EFFECT OF CONDITIONED-MEDIUM HUMAN ADIPOSE-DERIVED MESENCHYMAL STEM CELL IN APOPTOSIS OF BLADDER CANCER CELLS Mawdudi, Ari Alauddin; Hidayatullah, Furqan; Bachtiar, Indra; Rachman, Arif; Putri, Indri Lakhsmi; Castiglione, Fabio; Djatisoesanto, Wahjoe; Hakim, Lukman
Indonesian Journal of Urology Vol 28 No 1 (2021)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v28i1.653

Abstract

Objective: To determine the effect of conditioned medium human Adipose-Derived Mesenchymal Stem Cells (CM-hADMSC) on apoptosis of urothelial bladder cancer cells. Material & Methods: Bladder (5637) cancer cell lines cultured in conditioned media harvested from human adipose-derived mesenchymal stem cells (hADMSC). Flow cytometry tests were carried out using the Flowcytometry Acquisition cell sorting (FACS) Calibur to measure apoptosis. Results: There was a significant difference in the percentage of late apoptosis in the group receiving culture medium treatment: CM-hADMSC 1: 1 to the entire study group. Further analysis revealed no difference in the average percentage of late apoptosis in groups exposed to culture medium: CM-hADMSC 1: 2 and culture medium: CM-hADMSC 1: 4 (p> 0.05). Conclusion: CM-hADMSC at a 1: 1 dose concentration to culture medium obtain a significant increase of apoptosis in bladder cancer cells.
THE EFFECT OF CONDITIONED MEDIUM ADIPOSE DERIVED MESENCHYMAL STEM CELLS IN UROTHELIAL CARCINOMA CULTURE CELLS VIABILITY Prasetyo, Suryo; Hidayatullah, Furqan; Bachtiar, Indra; Rachman, Arif; Putri, Indri Lakhsmi; Castiglione, Fabio; Soebadi, Doddy M.; Hakim, Lukman
Indonesian Journal of Urology Vol 28 No 1 (2021)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v28i1.654

Abstract

Objective: This study aimed to gives a perspective in CM-ADMSCs effect in urothelial bladder cancer viability. Material & Methods: Human bladder cell carcinoma type 5637 was used as the subject of this in vitro study. This study contains four different groups: untreated control group, Culture medium: hADMSCs with 1:1, 1:2, and 1:4 concentration group. Each group consists of 6 replications to prevent bias of the study. Viability was determined with MTT assay methods and evaluation performed after 48 h exposure of conditioned medium. Results: A post hoc test was conducted to analyze the data. The 5637 bladder cancer cell line demonstrated significantly decreased viability after exposure to culture medium: CM-hADMSCs 1:1 (p: 0.002) compared to the negative control group, but there are no significant differences in viability between the control groups with groups that were exposed to culture medium: CM-hADMSCs 1:2 and culture medium: CM-hADMSCs 1:4 with p: 0.480 and p: 0.060 respectively. Conclusion: Decreased viability of urothelial bladder cancer cells after exposure to CM-hADMSCs occurs at a concentration of 1:1 and Dosage addition more than 1:1 concentration doesn’t give any advantages.
QUANTITATIVE MEASUREMENT OF BILATERAL CHEILORRHAPHY: A RETROSPECTIVE STUDY Zarasade, Lobredia; Wulandari, Pratidina; Indri Lakhsmi Putri
Jurnal Rekonstruksi dan Estetik Vol. 5 No. 1 (2020): Jurnal Rekonstruksi dan Estetik, June 2020
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (789.047 KB) | DOI: 10.20473/jre.v5i1.24324

Abstract

Highlights: There were no significant differences in anthropometric measurements across various groups indicating consistent results in these facial parameters. Bilateral cheilorrhaphy using the Djohansjah technique at the Surabaya CLP Center achieved satisfactory symmetry of the lips, nose, and philtrum, with consistent anthropometric measurements in preoperative cleft conditions. Abstract: Introduction: Bilateral cheilorraphy has higher complexity compared to unilateral cheilorraphy. Anthropometric measurements provide nasolabial identification of the surgery result objectively. This study aims to assess the outcome of bilateral cheilorrhaphy with the Djohansjah technique at Surabaya CLP Center. Methods: 26 patients underwent bilateral cheilorrhaphy from January 1 to December 31, 2018, at the Surabaya CLP Center. Anthropometric measurements were performed on control photos one-year post-surgery with the GIMP application (GNU Image Manipulation Software) version 2.10.12 to measure the cupid's bow width ratio, hemilabial length ratio, nasal width ratio, and philtrum ridge length ratio. A statistical analysis was performed using Independent Sample t-Tes and Mann-Whitney Test. Results: An anthropometric size difference test based on preoperative condition was performed. No significant difference of the cupid's bow width ratio, hemilabial length ratio, nasal width ratio, and philtrum ridge length ratio between the group of identical cleft lip and unidentical cleft lip with p > 0.05 was found. Likewise, there was no difference between the identical cleft alveolar and unidentical cleft alveolar, as well as the group with or without cleft palate. Conclusions: Symmetry of lips, nose, and philtrum was achieved with bilateral cheilorrhaphy with the Djohansjah technique at the Surabaya CLP Center and there was no significant difference in cupid's bow width ratio, hemilabial length ratio, nasal width ratio, and philtrum ridge length ratio on preoperative cleft condition.
ORTHOGNATHIC SURGERY COMBINED WITH ORTHODONTIC TREATMENT IN A PATIENT WITH BILATERAL CLEFT LIP, PALATE AND ALVEOLUS, WITHOUT ALVEOLAR BONE GRAFT: A CASE REPORT Siswanto, Yudi; Hutagalung, Magda Rosalina; Sjamsudin, Jusuf; Indri Lakhsmi Putri
Jurnal Rekonstruksi dan Estetik Vol. 3 No. 1 (2018): Jurnal Rekonstruksi dan Estetik, June 2018
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1329.008 KB) | DOI: 10.20473/jre.v3i1.24365

Abstract

Highlights: The orthognathic surgery combined with orthodontic intervention, leads to positive functional and aesthetic outcomes in individuals diagnosed with bilateral cleft lip and palate. It emphasizes the continued importance of adhering to the standard protocol, including alveolar bone grafting before permanent canine eruption, to achieve optimal outcomes. Abstract: Introduction: The incidence of cleft lip and palate is 8 in every 10,000 live births. A patient with this condition experiences a deficiency in maxillary growth. Maxillary hypoplasia leads to malocclusion and skeletal disharmony. Orthognathic surgery at skeletal maturity is the standard procedure at the end of the protocol to correct maxillary hypoplasia resulting in malocclusion not correctable with orthodontics alone. Case Illustration: We report the result of orthognathic surgery performed on a 23 year old male with complete bilateral cleft lip, palate, and alveolus. We proceeded with bimaxillary surgery despite the alveolar cleft. We also recorded a neglected alveolar cleft in which he should have had undergone alveolar bone graft prior to the current procedure. The pre-maxillary segment was stabilized with miniplate followed by Le Fort 1 advancement and mandibular setback guided by an occlusal wafer. Malar augmentation was done by onlay bone grafts. Mandibulo-maxillary fixation was maintained. Postoperatively, a good occlusion and better facial harmony were achieved. He was planned to undergo a septorhinoplasty in the near future. Discussion: Despite adequate treatments following the protocol recommended by many centres, some patients developed some degree of maxillary hypoplasia. A quarter of this population need osteotomies and Le Fort I maxillary osteotomy is the most common procedure to correct retrognathic maxilla. Conclusion: Orthognathic surgery combined with orthodontic treatment in a patient with bilateral cleft lip and palate provided good functional and aesthetic result. However, this procedure cannot replace the standard protocol of having an alveolar.
THE EPIDEMIOLOGY OF PLASTIC SURGERY CASES IN A TERTIARY GENERAL HOSPITAL IN SURABAYA, INDONESIA Dwika Intania Riano; Lavonia Berlina Adzalika; Indri Lakhsmi Putri; Rachmaniar Pramanasari
Jurnal Rekonstruksi dan Estetik Vol. 8 No. 1 (2023): Jurnal Rekonstruksi dan Estetik, June 2023
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jre.v8i1.45272

Abstract

Highlights: Medical data registries play a crucial role in improving medical knowledge and enhancing patient care. Burn injuries, microtia, and orofacial clefts were identified as the most common occurrences among the patients The demographic patterns observed provide valuable insights into the patient population seeking plastic surgery services. Abstract: Introduction: Medical data registries are useful databases with well-defined data collection mechanisms. A well-designed and implemented registry can give surgeons a wealth of data for research and quality improvement efforts. The aim is describe the epidemiology of plastic surgery cases in a tertiary general hospital in Surabaya, Indonesia. Methods: A retrospective assessment of patients' medical records from 2016 to 2019 at Plastic Reconstructive and Aesthetic Surgery Unit, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia was conducted. A variety of factors were recorded and evaluated, including the patients' age, gender, diagnosis, and year. Results: We found that among 736 individuals' medical records during a four-year period, burn injuries (17.4%), microtia (11.7%), and orofacial clefts (11.5%) were the most prevalent occurrences. The majority of patients with burn injuries (31.3%), those with microtia (39.5%), those with cleft lip and palate (33%), and those with microtia (between the ages of 15 and 24) were all between the ages of 45 and 64. Patients who were men (52.6%) outnumbered those who were women (47.4%). This data indicates that there were more patients in 2019 than in previous years (397.%). Conclusion: The analysis of plastic surgery cases revealed a steady increase in the number of cases each year. Burns accounted for the biggest percentage of patient requests for care (17.4%). The majority of patients were male, and 21.9% of them were between the ages of 15 and 24 who were seeking care most frequently.
Co-Authors Arif Rachman Castiglione, Fabio Doddy M. Soebadi Dwika Intania Riano Furqan Hidayatullah Hutagalung, Magda Rosalina Indra Bachtiar Jusuf Sjamsudin Lavonia Berlina Adzalika Lukman Hakim Mawdudi, Ari Alauddin Prasetyo, Suryo Rachmaniar Pramanasari wahjoe djatisoesanto Wulandari, Pratidina Yudi Siswanto Zarasade, Lobredia