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Hubungan Konsumsi Harian Rokok Terhadap Antibodi IgG S1RBD Pasca Vaksinasi COVID-19 pada Civitas Akademik Putri, Amalia; Norsiah, Wahdah; Herlina, Tini Elyn; H. Haitami; Rakhmina, Dinna
Jurnal Karya Generasi Sehat Vol. 1 No. 1 (2023): Edisi Desember 2023
Publisher : Poltekkes Kemenkes Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/jkgs.v1i1.29

Abstract

Vaksinasi dinilai sebagai cara paling efektif untuk penanganan pandemi akibat COVID-19. Vaksinasi memiliki efek yang berbeda pada tiap individu. Kandungan nikotin dalam rokok diduga menghambat aktivasi kekebalan bawaan dan adaptif, sehingga mempengaruhi pembentukan antibodi yang diinduksi dari vaksinasi.Tujuan penelitian ini untuk mengetahui ada atau tidaknya hubungan konsumsi harian rokok seseorang dengan kadar antibodi IgG S1RBD. Jenis penelitian yang digunakan adalah survei analitik dengan metode cross sectional study pada civitas akademik yang memiliki kebiasaan merokok. Hasil penelitian dari 28 responden didapatkan kadar rata-rata antibodi IgG S1RBD pada responden dengan konsumsi harian rokok 1-10 batang/ hari sebesar 255,59 IU/mL, 11-20 batang/ hari sebesar 173,15 IU/mL, lebih dari 20 batang/hari sebesar 143,79 IU/mL, dan pada non perokok sebesar 279,21 IU/mL. Uji statistik menunjukkan nilai signifikansi 0,000 sehingga disimpulkan semakin tinggi konsumsi harian rokok seseorang maka semakin menurun antibodi IgG S1RBD dalam tubuhnya.
Uji Efektivitas Air Perasan Daun Jeruk Limau Kuit ( Citrus hystrix ) Sebagai Insektisida Nabati Terhadap Mortalitas Kutu Rambut Pediculus humanus capitis Secara In Vitro Pusvita, Nidha; Thuraidah, Anny; Rifqoh, Rifqoh; Rakhmina, Dinna
Jaringan Laboratorium Medis Vol. 4 No. 2 (2022): November 2022
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v4i2.8579

Abstract

Lemongrass leaves are a typical plant of South Kalimantan which contain anti-insecticide, namely secondary metabolites such as alkaloids, saponins, tannins, steroids and triterpenoids. Pediculosis is a disease caused by a tick infection which is still neglected and becomes a health problem. One way to get rid of head lice is to use natural ingredients that contain anti-insecticide substances. This study aims to examine the possibility of using natural ingredients in lime leaves as vegetable insecticides against head lice mortality. The research method used is experimental, with a research design that is a post-test only control group, which measures and compares the mortality variable of Pediculus humanus capitis after being treated with lime leaf juice with concentrations of 10%, 30%, 60%, 100% during 1, 6, 12 and 24 hours and compared them with the negative control group with aquadest and the positive control with pemethrin. The sample of this study was lime leaf extract which was extracted by the method of squeezing using water. From the results of the study obtained the highest percentage of death at 12 and 24 hours with 100% mortality at a concentration of 100%. Based on the results of statistical tests using mortality observation data, the LC99 values were obtained within 1 hour (197.678%), 6 hours (126.055%), 12 hours (89.847%), and 24 hours (60.758%). Based on the results of the analysis of the data obtained, it can be concluded that there is effectiveness of lime leaf juice (Citrus hystrix) on the mortality of head lice (Pediculus humanus capitis) in vitro. Then the juice of lime leaves can be used as an alternative to getting rid of head lice with natural ingredients.