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Predictors of Virological Failure in HIV Patients Receiving FirstLine Antiretroviral Therapy with Good Adherence Kurniawan, Farid; Djauzi, Samsuridjal; Yunihastuti, Evy; Nugroho, Pringgodigdo
Jurnal Penyakit Dalam Indonesia Vol. 4, No. 1
Publisher : UI Scholars Hub

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Abstract

Introduction. Antiretroviral therapy (ART) effectively suppress HIV replication. Viral load (VL) measurement is better predictor than clinical or immunological criteria to evaluate success or failure of ART. However, in country with limited resources, viral load measurement is not easily accessible by HIV patients receiving ART. Therefore, it is necessary to know which factors that can predict virological failure. In previous studies, adherence was an important factor for suppression of HIV viral load. This study is aimed to know predictors of virological failure in HIV patients receiving recent first line ART regimen with good adherence in Indonesia. Methods. A retrospective cohort study was conducted among adult HIV patients in Out-patient Clinic of Cipto Mangunkusumo Hospital that started ART during periode of January 2011-June 2014. HIV patients with good adherence that had viral load data 6-9 months after initiation of ART were included in this study. Virological failure was defined as viral load ≥ 400 copies/ mL after minimum of 6 months therapy with good adherence. Age at starting ART, risk factor for HIV infection, HIV clinical stage, HIV-TB co-infection, baseline CD4 value, CD4 count increase, baseline hemoglobin level and body mass index, weight changes during therapy, and ART based regimen were analyzed in this study. Results. A total of 197 patients were included in this study. Virological failure was found in 21 patients (10,7%). CD4 increase /mm3 after minimum 6 months of ART was predictor of virological failure (p = 0,003; OR 5,802, 95%CI 1,842-18,270). Conclusion. CD4 increase /mm3 after minimum 6 months therapy can predict virological failure in HIV patients receiving first line ART with good adherence
Instrument Test Service Forehand & Backhand Tenis Meja Kurniawan, Farid; Safari, Indra; Sudrazat, Adang
Jurnal Ilmu Keolahragaan Undiksha Vol. 10 No. 3 (2022): October
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23887/jiku.v10i3.50719

Abstract

Masalah yang terjadi saat ini yaitu belum ada alat uji untuk menilai kemampuan seorang atlet sebelum dan sesudah menyelesaikan suatu program Latihan. Hal ini berdampak pada penilaian kemampuan atlet yang kurang. Penelitian ini bertujuan untuk mengembangkan Instrument tes service forehand dan backhand tenis meja. Jenis penelitian ini yaitu pengembangan. Metode yang digunakan dalam penelitian ini adalah metode penelitian Research and Development (R&D). Karakteristik partisipan dalam penelitian ini di mulai dari usia kadet, junior, remaja, dan Senior sebanyak 100 orang. Metode yang digunakan dalam mengumpulkan data yaitu observasi dan kuesioner. Instrumen yang digunakan dalam mengumpulkan data yaitu kuesioner. Teknik yang digunakan untuk menganalisis data yaitu analisis deskriptif kualitatif dan kuantitatif. Analisis data untuk uji validitas menggunakan CVR (Content Value Ratio) dan reliabilitas menggunakan Alpha Crobanch. Hasil analisis data yaitu hasil validitas instrument service forehand dan backhand memiliki validitas validitas yang tinggi serta memiliki reliabilitas instrument service forehand yang reliabel. Disimpulkan bahwa pengembangan instrument service forehand dan backhand tenis meja ini dapat dinyatakan layak digunakan.
SIMULACRA AND HYPERREALITY IN BLADE RUNNER 2049 (2017) Kurniawan, Farid
LINGUA LITERA : journal of english linguistics and literature Vol 9 No 2 (2024): Journal Lingua Litera
Publisher : STBA Prayoga Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55345/stba1.v9i2.253

Abstract

Today's world is characterized by the era of simulation and hyperreality, with manyartificial realities that take over or even replace reality itself. Many aspects can now becreated or simulated through the manipulation of advanced technology, Jean Baudrillardcalls this the phenomenon of “hyperreality”. The movie Blade Runner 2049 tells the storyof this condition where artificial things are flooding the reality, and the replicants can evenreplace the role of humans themselves. In this movie, the artificially engineered human iscalled 'replicant'. Jean Baudrillard's simulacra analysis is the methodology that theresearcher uses to analyze the film, as well as taking a qualitative approach. This method isdone by observing the entire content of the movie, as well as examining various signs, bothverbal and non-verbal, to see the relationship between the Blade Runner 2049 with JeanBaudrillard's hyperreality concept. The phenomenon of artificial humans or replicants, aswell as advanced virtual technology and advanced manipulation by technology is veryrepresentative of Baudrillard's thinking. Where the world of the future, depicted as full ofdarkness due to the development of technology itself. Not only does it replace the role ofhumans, but even trying to surpass God.