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All Journal Agora Padjadjaran Journal of Dentistry
Anthony Hartanto, Anthony
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Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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The effect of apple (Malus Domestica) juice on the damage of mice liver cells due to paracetamol treatment Hartanto, Anthony; Dardjan, Murnisari; Kintawati, Silvi
Padjadjaran Journal of Dentistry Vol 21, No 2 (2009): July
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (163.675 KB) | DOI: 10.24198/pjd.vol21no2.14095

Abstract

The liver is an important organ for body metabolism process. Liver disease is one of serious health problems in developing countries including Indonesia. Liver damage is caused by viral infection, toxic agent exposure (medications, alcohol), hormonal disturbance, neoplasm and autoimmune diseases. The use of high dose paracetamol to reduce pain also leads to liver damage. Apple (Malus domestica) juice is a natural anti oxidant agent. This laboratory experimental study was performed to discover the effect of giving apple juice on damaged cell regeneration due to the use of paracetamol. The study was performed in 21 male mice from Swiss-Webster strain that were divided into group I, II, and III. Group, I served as control while group II received 1 mg/ml paracetamol dose for 5 days and Group III received 1 mg/ml paracetamol for 5 days and 1 ml of apple juice on the 5th to 10th day. The observation of the mice liver cells was conducted using a light microscope with 400x magnification to get the number of necrotic liver cells per view field. The results of this study showed a difference in the number of necrotic liver cells between Group II and III. ANOVA statistical test ( = 0.05) concluded that apple juice significantly helps regeneration process in damaged liver cells caused by paracetamol.
PENGARUH KUALITAS PRODUK, KUALITAS LAYANAN, DAN LINGKUNGAN FISIK TERHADAP LOYALITAS PELANGGAN MELALUI KEPUASAN PELANGGAN SEBAGAI VARIABEL MEDIASI DI DE MANDAILING CAFE SURABAYA Hartanto, Anthony
Agora Vol 7, No 1 (2019): Agora, Jurnal Mahasiswa Manajemen Bisnis
Publisher : Agora

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (503.239 KB)

Abstract

Penelitian ini bertujuan untuk melihat pengaruh kualitas produk, kualitas layanan, dan lingkungan fisik terhadap loyalitas pelanggan dan kepuasan pelanggan di De Mandailing Cafe Surabaya. Penelitian ini menggunakan metode penelitian kuantitatif. Sampel dalam penelitian ini sebanyak 100 orang responden yang diambil dengan teknik purposive sampling. Teknik analisis data menggunakan uji outer model, uji inner model, dan uji hipotesis (uji t). Proses perhitungan menggunakan program SmartPLS 3.0 for windows. Hasil penelitian menunjukkan bahwa kualitas layanan, dan lingkungan fisik berpengaruh positif dan signifikan terhadap kepuasan pelanggan. Dari hasil analisa penelitian juga ditemukan bahwa kepuasan pelanggan juga berpengaruh positif dan signifikan terhadap loyalitas pelanggan. Sementara variabel kualitas produk ditemukan tidak memiliki pengaruh yang signifikan terhadap kepuasan pelanggan. Faktor yang paling berpengaruh terhadap kepuasan pelanggan pada De Mandailing Cafe adalah kualitas layanan
Co-Authors Murnisari Dardjan, Murnisari Silvi Kintawati