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All Journal International Research Journal of Management, IT & Social Sciences International Journal of Education Research and Development
R. Jamuna, R.
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Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Languange, Linguistic, Communication & Media Mathematics Social Sciences

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Data Mining Technique Applied To DNA Sequencing Jamuna, R.
International Research Journal of Management, IT & Social Sciences Vol 2 No 7: July 2015
Publisher : International Journal of College and University (IJCU)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21744/irjmis.v2i7.70

Abstract

CpG islands (CGIs) play a vital role in genome analysis as genomic markers.  Identification of the CpG pair has contributed not only to the prediction of promoters but also to the understanding of the epigenetic causes of cancer. In the human genome [1] wherever the dinucleotides CG occurs the C nucleotide (cytosine) undergoes chemical modifications. There is a relatively high probability of this modification that mutates C into a T. For biologically important reasons the mutation modification process is suppressed in short stretches of the genome, such as ‘start’ regions. In these regions [2] predominant CpG dinucleotides are found than elsewhere. Such regions are called CpG islands. DNA methylation is an effective means by which gene expression is silenced. In normal cells, DNA methylation functions to prevent the expression of imprinted and inactive X chromosome genes. In cancerous cells, DNA methylation inactivates tumor-suppressor genes, as well as DNA repair genes, can disrupt cell-cycle regulation. The most current methods for identifying CGIs suffered from various limitations and involved a lot of human interventions. This paper gives an easy searching technique with data mining of Markov Chain in genes. Markov chain model has been applied to study the probability of occurrence of C-G pair in the given   gene sequence. Maximum Likelihood estimators for the transition probabilities for each model and analgously for the  model has been developed and log odds ratio that is calculated estimates the presence or absence of CpG is lands in the given gene which brings in many  facts for the cancer detection in human genome.
Challenges Faced by Visually Impaired Teachers Working in Blind Schools in Online Teaching During Covid 19 Zuber, Mohd.; Jamuna, R.; Muthmainnah, Muthmainnah
International Journal of Education Research and Development Vol. 1 No. 2 (2021): October
Publisher : Yayasan Corolla Education Centre

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52760/ijerd.v1i2.8

Abstract

This study aims to examine the isssues in translating cultural terms between English and Malay. Thus, the researcher will thoroughly introduce the issue and analyse the findings by collecting data from books, conversation and social media, making this research a qualitative research. Thus, this research paper seeks to find a practical and professional solution for translators who are having the same issues whilst translating. In addition to that, the researcher has used Mona Baker’s equivalence typology to help complete this research.
Co-Authors Muthmainnah Muthmainnah Zuber, Mohd.