Monica Suryani
Jurusan Farmasi, Fakultas Farmasi dan Ilmu Kesehatan, Universitas Sari Mutiara Indonesia

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Effect Of The Addition Of VCO (Virgin Coconut Oil) Oil In Clay Mask Formulation Alfa-Tocoferol As Anti-Aging Monica Suryani; Suharyanisa Suharyanisa; Jon Kenedy Marpaung
Jurnal EduHealth Vol. 14 No. 03 (2023): Jurnal EduHealt, Edition September 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54209/jurnaleduhealth.v14i3.2640

Abstract

Premature aging is a natural process in life. Usually premature aging is caused by excessive sun exposure, pollution, and stress. Vitamin E and lauric acid and oleic acid from VCO oil as antioxidant that can protect the skin from free radicals and which work as maoisturizers to prevent dry skin. to formulate and evaluate clay mask preparations from alpha-tocopherol and vco oil as anti-aging. this research was conducted experimentally. The preparations of Clay mask was carried out by adding alpha-tocopherol and vco oil with concentrations of 1%:5% (F1), 1%:7% (F2), and 1%:9% (F3) respectively into the base of the clay mask and preparations. The blank (F0) was used as a clay mask base witout the additionof alpha-tocopherol and Vco oil. Tests on clay mask preparations include homogeneity test, stability test, pH test, irritation test, mask drying time test and anti-aging effectiveness measurement test using a skin analyzer on volunteers‟ faces. Parameters tested include water content, large pores, many blemishes and wrinkles. The treatment was carried out for four weeks. the results of the study showed that alpha-tocopherol and vco oil could be formulated in clay mask preparations and werw stable for 12 weeks of storage, homogeneous mask preparations, pH 5,6-6,1, stable during storage, could not irritate the skin. The higher the concentration used indicates a change in skin condition for the better with the highest concentration for four weeks for thr better with increasing water content (22,33 to 40,66), smaller pore (39,66 to 20,00), reduced blemishes (40,66 to 21,00), less wrinkles (34,00 to 16,00). alpha-tocopherol with vco oil can be formulated into a clay mask preparation and its good effevtiveness as an anti-aging can be seen in clay mask with 9% vco oil concentration. Imparoved skin condition with increased moisture content (percent recovery 33,54%), smaller pores (prcent recovery 45,96%), reduced blesmishes (percent recovery 49,11%) and reduced wrinkles (percentage recovery 44,85%). However, for some people, using a clay mask can cause allergic reactions and itching. In addition, excessive use of clay masks can also make the skin dry, which triggers excess oil production. It is hoped that future researchers will be able to make clay mask formulas with different samples.
TESTING OF THE ACTIVITY OF FLAVONOIDS FROM THE ETHANOL EXTRACT OF MELINJO LEAF (GNETUM GNEMON LINN.) AS AN ANTIOXIDANT Natanael Priltius; Monica Suryani; Devina Chandra; Nadya Purba
Jurnal Scientia Vol. 12 No. 03 (2023): Education, Sosial science and Planning technique, 2023 (June-August)
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58471/scientia.v12i03.1809

Abstract

Indonesia has various types of plants that have the potential to be developed into modern medicines. The main source of antioxidants comes from plants. Antioxidants can be defined as compounds capable of delaying, slowing down, or inhibiting oxidation reactions. An antioxidant group that has great potential has the ability to prevent the occurrence of premature aging, inflammatory diseases, and degenerative diseases. The availability of antioxidants in the body must be maintained and increased to be able to ward off free radicals. The purpose of this study was to determine or study the nature of the activity of flavonoid compounds from the ethanol extract of melinjo leaves (Gnetum gnemon Linn.), which can be used as antioxidants using the DPPH (1,1-diphenyl-2-pikrilhidrazyl) method. The sample used in this study was melinjo leaves obtained from Kutacane, Southeast Aceh. Samples were extracted using ethanol solvent, and antioxidant activity testing was carried out by visible spectrophotometry using the DPPH (1,1-diphenyl-2-picrylhidrazyl) method. This method uses an analysis of the Inhibitory Concentration of 50% (IC50) as a determination of free radical scavenging activity; this value describes the concentration of the test compound that can trap free radicals by 50%. The results of this study indicate that the IC50 value of the ethanol extract of melinjo leaves has a very strong effect, with an IC50 value of 28.92 μg/mL. In this study using quercetin as a reference solution, which has a very strong effect with an IC50 value of 6.2933 μg/mL, so it can be concluded that the ethanol extract of melinjo leaves has activity asan antioxidant using the DPPH method.