Natanael Priltius
Fakultas Farmasi Dan Ilmu Kesehatan Universitas Sari Mutiara Indonesia

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TESTING OF THE ACTIVITY OF FLAVONOIDS FROM THE ETHANOL EXTRACT OF MELINJO LEAF (GNETUM GNEMON LINN.) AS AN ANTIOXIDANT Natanael Priltius; Monica Suryani; Devina Chandra; Nadya Purba
Jurnal Scientia Vol. 12 No. 03 (2023): Education, Sosial science and Planning technique, 2023 (June-August)
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58471/scientia.v12i03.1809

Abstract

Indonesia has various types of plants that have the potential to be developed into modern medicines. The main source of antioxidants comes from plants. Antioxidants can be defined as compounds capable of delaying, slowing down, or inhibiting oxidation reactions. An antioxidant group that has great potential has the ability to prevent the occurrence of premature aging, inflammatory diseases, and degenerative diseases. The availability of antioxidants in the body must be maintained and increased to be able to ward off free radicals. The purpose of this study was to determine or study the nature of the activity of flavonoid compounds from the ethanol extract of melinjo leaves (Gnetum gnemon Linn.), which can be used as antioxidants using the DPPH (1,1-diphenyl-2-pikrilhidrazyl) method. The sample used in this study was melinjo leaves obtained from Kutacane, Southeast Aceh. Samples were extracted using ethanol solvent, and antioxidant activity testing was carried out by visible spectrophotometry using the DPPH (1,1-diphenyl-2-picrylhidrazyl) method. This method uses an analysis of the Inhibitory Concentration of 50% (IC50) as a determination of free radical scavenging activity; this value describes the concentration of the test compound that can trap free radicals by 50%. The results of this study indicate that the IC50 value of the ethanol extract of melinjo leaves has a very strong effect, with an IC50 value of 28.92 μg/mL. In this study using quercetin as a reference solution, which has a very strong effect with an IC50 value of 6.2933 μg/mL, so it can be concluded that the ethanol extract of melinjo leaves has activity asan antioxidant using the DPPH method.
Pelembab Bibir Lip Balm dengan Memanfaatkan Ekstrak Daun Anggur (Vitis vinifera L.) Devina Chandra; Steven Tandiono; Manuppak Irianto Tampubolon; Natanael Priltius
An-Najat Vol. 1 No. 2 (2023): MEI : An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v1i2.189

Abstract

Grape leaves (Vitis vinifera L.) contain vitamin E and flavonoids which had the potential to act as a moisturizer by preventing the loss of body fluids from the surface of the skin, so the lips will not dry quickly. This study aims to determine the effectiveness of grape leaf extract in the form of lip balm lip balm that meets quality. Grape leaves are made in the form of thick extracts and formulated into lip balms with various concentrations of 0, 1, 3 and 5%. The results showed that grape leaf extract which was formulated in the form of lip balm preparations had homogeneous properties and different colors for each concentration, the higher the concentration, the light green color became dark green. Lip balm preparations have a melting point value of each formula 56.2-61.0℃; strength test value of 220-300 g; pH test value 5.56-5.94; stable at room temperature for 4 weeks, and does not cause irritation such as erythema, papules and vesicles. The effectiveness of this lip balm preparation was tested using a skin analyzer with a humidity value of 9.43 for each formula; 17.70; 28.95; and 39.93%. The conclusion of this study is that grape leaf extract lip balm has a high level of moisture at a concentration of 5% (F3) and has a significant difference with other formulas.
Formulasi Dan Pengujian Sediaan Deodorant Spray Yang Mengandung Ekstrak Daun Kemangi (Ocimum Basilicum L.) Terhadap Bakteri Staphylococcus Aureus Devina Chandra; Manuppak Irianto Tampubolon; Natanael Priltius
Jurnal Siti Rufaidah Vol. 1 No. 4 (2023): November : Jurnal Siti Rufaidah
Publisher : PPNI UNIMMAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jasira.v1i4.37

Abstract

Basil leaves are very rich in nutritious substances. Among them are beta carotene, vitamin C, macro minerals (calcium, phosphorus, magnesium). This plant is included in the Lamiaceae family which contains various chemical compounds, including phenols, saponins, alkaloids, flavonoids, tannins, and essential oils. The benefits of basil have been widely applied in people's lives as traditional medicine, for example, basil leaves are used to treat, cough, colds and so on. Body odor can be caused by several factors such as genetic factors, psychological conditions, food factors, obesity factors and clothing materials used.One of the triggers of body odor due to bacterial infection, namely Staphyloccous aureus bacteria.This study aims to formulate deodorant spray ethanol extract of basil leaves, test the physical properties of deodorant spray preparations, and determine whether the preparation of deodorant spray ethanol extract of basil leaves can inhibit staphylococcus aureus bacteria. Physical tests were carried out on days 0 (after manufacture) and 7 with the results of the organoleptical physical test of the preparation having a distinctive odor of basil, brownish yellow in color, It has a pH of 4 which corresponds to the pH of the skin, and experiencing an increase in viscosity on day 7 examination. The antibacterial test results of formulations 1, 2, and 3 showed inhibition of the banteri.
Sosialisai Tentang Pentingnya Vitamin C Untuk Kesehatan Tubuh Dan Donor Darah Di Kecamatan Medan Helvetia, Kota Medan Monica Suryani; Manahan Situmorang; Natanael Priltius
Compromise Journal Community Proffesional Service Journal Vol. 1 No. 4 (2023): Compromise Journal : Community Proffesional Service Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/compromisejournal.v1i4.194

Abstract

The important role of ascorbic acid or Vitamin C in the body is for metabolic processes and tissue repair. Antioxidants from Vitamin C can help protect cells from free radicals. Vitamin C can protect skin and produce collagen. Collagen is a natural protein in the body that forms the structure of the skin, whose production can decrease due to free radicals and aging. Vitamin C can maintain collagen production so that skin looks healthy and firm. Therefore, Vitamin C can work to maintain beauty and health. The highest daily dose of vitamin C is 1,000 milligrams/day. In this service activity, two activities were carried out separately, namely socialization about the importance of Vitamin C for body health and blood donation in Medan Helvetia District, Medan City to provide information to residents of Medan Helvetia District regarding the importance of Vitamin C for body health. Blood donation is also carried out to have many impacts both on the health of the donor and the recipient. This activity was also carried out to increase awareness regarding the health benefits of consuming Vitamin C.
Formulasi Sediaan Emulgel Ekstrak Daun Tanaman Leunca (Solanum nigrum) Sebagai Antibakteri Staphylococcus aureus pada Kulit Jon Kenedy Marpaung; Manahan Situmorang; Yanti Musyawarah; Natanael Priltius
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 2 No. 4 (2024): Oktober: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v2i4.563

Abstract

Emulgel is a moisturizing topical preparation that is able to soften the skin and protect it from damage. The leaves of the leunca plant have antibacterial and anti- inflammatory properties. Staphylococcus aureus is a gram-positive bacteria that can be found on human skin. This research aims to find out whether leunca (solanum nigrum) leaf extract can be formulated into an emulgel preparation that meets physicochemical quality, find out whether the resulting emulgel preparation of leunca leaf extract (solanum nigrum) can act as an antibacterial for staphylococcus and find out whether there are differences in the concentration of leunca leaf extract emulgel preparations. (solanum nigrum) affects its effectiveness as an antibacterial for Staphylococcus. This research method used. This research was carried out experimentally with emulgel preparations from leunca leaf extract with concentrations of 2%, 4% and 6% with emulgel evaluation. Based on the experimental results, it was concluded that leunca (solanum nigrum) leaf extract could be formulated F0, F1, F2 and F3 to meet the Organoleptic Test, Homogeneity Test, pH Test, Adhesion Test, Spreadability Test, Viscosity Test and Irritation Test. The emulgel preparation formulation from leunca (solanum nigrum) leaf extract showed potential as an antibacterial for Staphylococcus aureus with a DDH value greater than 20 mm, namely 20,31 to 21,83.
Formulasi dan Evaluasi Sediaan Sabun Mandi Cair Menggunakan Sari Buah Bit (Beta Vulgaris L.) Sebagai Pelembab Kulit Devina Chandra; Natanael Priltius; Betharina Br Tarigan
The Journal General Health and Pharmaceutical Sciences Research Vol. 2 No. 2 (2024): June : The Journal General Health and Pharmaceutical Sciences Research
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/tjghpsr.v2i2.331

Abstract

Liquid bath soap is a liquid preparation used to clean the skin, made from soap base ingredients with added surfactants, foam stabilizers and fragrances, which is used when bathing without irritating to the skin. Liquid bath soap is made by saponifying oil and fat with KOH. Quality soap must have high detergent power, can be used on various types of materials and remain effective at different temperatures and water levels. In this study, this liquid bath soap used the addition of beetroot juice which is rich in benefits for skin health. The aim of this research is to find out whether beetroot juice formulated into liquid bath soap will have a moisturizing effect on the skin, and determine the concentration of beetroot juice as the best skin moisturizer. This research is made into four formulas. First without the addition of F0 Beetroot Juice (0%), Second with the addition of F1 Beetroot Juice (10%), Third with the addition of F2 Beetroot Juice (15%), Fourth with the addition of F3 Beetroot Juice (20%). From the results of this research, we got good results in the liquid bath soap formulation with the addition of 20% beetroot juice (F3), and from the results, the F3 formulation (20%) was also the most preferred by the panelists for the aroma and color of the fruit juice liquid bath soap beet.