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All Journal Jurnal Surya Medika PharmaCine: Journal of Pharmacy, Medical and Health Science
Sridevi Anggraini
Universitas Singaperbangsa Karawang
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

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Artikel Review: Tingkat Kepatuhan dan hal - hal yang yang Mempengaruhi Kepatuhan dalam Penggunaan Obat Antibiotik: Review Article: Level of Complaince and Things Impacting Compliance in Antibiotic Drug Use Indah Laily Hilmi; Salman Salman; Sridevi Anggraini
Jurnal Surya Medika (JSM) Vol. 9 No. 2 (2023): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v9i2.5684

Abstract

Infectious diseases are still an important health problem in Indonesia, especially in developing countries. Antibiotics are drugs that are often used as a treatment for infectious diseases caused by bacteria with a mechanism of action by killing or inhibiting the growth of bacteria and with relatively little toxicity to humans. The use of antibiotics must be used rationally if used correctly it will reduce the level of antibiotic resistance. Antibiotic resistance is a condition where the inability of antibiotics to fight bacteria due to bacterial mutations. Cases of resistance reported by the Deputy Minister of Health of the Republic of Indonesia, the prevalence of antibiotic resistance continues to increase. Compliance with the use of antibiotic drugs is an effort to overcome the prevention of resistance in patients receiving antibiotic therapy, by knowing several factors related to patient adherence including demographic factors, belief behavior factors, drug information giving factors and counseling factors.
Studi Literatur : Molekular Docking Senyawa Anti Covid-19 terhadap Enzim 3c-Like Protease Cantila Dewi Berliana; Nurma Dwi Rahmawati; Regita Nailuvar; Sridevi Anggraini; Syfa Dwi Andini; Lina Nurfadhila
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol. 3 No. 2 (2022): PharmaCine : Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v3i2.8034

Abstract

Latar Belakang : Organization (WHO) menyatakan COVID-19 sebagai pandemi pada 11 Maret 2020 (Kementerian Kesehatan Republik Indonesia, 2020). COVID-19 menyebar dengan cepat melalui transmisi kontak, aerosol, dan droplet). SARS-CoV-2 adalah virus beta-korona yang menginfeksi saluran pernapasan bagian atas (yaitu sinus, hidung, dan tenggorokan) dan saluran pernapasan bagian bawah (yaitu tenggorokan dan paru-paru). Pasien biasanya mengalami gejala mulai dari ringan hingga berat yang mengancam jiwa, termasuk batuk, sakit tenggorokan, demam, dispnea, kelelahan, diare, sindrom gangguan pernapasan akut, sepsis dan syok septik Tujuan: mengetahui interaksi senyawa anti virus dengan enzim papain-like protease pada covid-19 melalui penambatan molecular untuk memprediksi sifat makromolekul protein Metode: studi literatur. Hasil: beberapa tumbuhan memiliki sifat anti covid, 9 senyawa uji anti virus yang di docking dengan enzim Papain-like protease menghasilkan senyawa uji terbaik yaitu umifenovir. Catechin gallat (CG) memiliki score docking -11,407 dan epicatechin gallat (ECG) memiliki score docking -111.391. Kedua senyawa ini memiliki potensi sebagai alternative pengganti remdesivir dalam menghambat main protease SARS-CoV-2. Kata Kunci : Anticovid-19, Molecular docking, covid.
Co-Authors Cantila Dewi Berliana Indah Laily Hilmi Lina Nurfadhila Nurma Dwi Rahmawati Regita Nailuvar Salman Salman Syfa Dwi Andini