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All Journal Journal of Applied Pharmaceutical Research Indonesian Journal of Cardiology
Yogendra Singh, Yogendra
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Health Professions Medicine & Pharmacology

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A comprehensive review on microbial degradation of plastic waste Kumar, Sahni; Teotia, U.V.S; Singh, Yogendra
Journal of Applied Pharmaceutical Research Vol 5 No 4 (2017)
Publisher : Creative Pharma Assent

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18231/2348-0335.2017.0009

Abstract

Plastic is a broad name given to different polymers with high molecular weight, which can be degraded by various processes. However, considering their abundance in the environment and their specificity in attacking plastics, biodegradation of plastics by microorganisms and enzymes seems to be the most effective process. When plastics are used as substrates for microorganisms, evaluation of their biodegradability should not only be based on their chemical structure, but also on their physical properties (melting point, glass transition temperature, crystallinity, storage modulus etc.). In this review, microbial and enzymatic biodegradation of plastics and some factors that affect their biodegradability are discussed. Plastics have become an important part of modern life and are used in different sectors of applications like packaging, building materials, consumer products and much more. Each year about 100 million tons of plastics are produced worldwide. Degradation is defined as reduction in the molecular weight of the polymer. The Degradation types are (a). Chain end degradation/de-polymerization (b).Random degradation/reverse of the poly condensation process. Biodegradation is defined as reduction in the molecular weight by naturally occurring microorganisms such as bacteria, fungi, and actinomycetes. That is involved in the degradation of both natural and synthetic plastics. 
Screening of poly vinyl chloride degrading bacteria from plastic contaminated area of Baddi Kumar, Sahni; Teotia, UVS; Singh, Yogendra
Journal of Applied Pharmaceutical Research Vol 5 No 3 (2017)
Publisher : Creative Pharma Assent

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18231/2348-0335.2017.0005

Abstract

Plastic wastes are posing ever increasing environmental concerns. Recent research works have shown that most of the constituents of plastics can be degraded by microbes and the film plastics can be treated by microbial systems. In this study, poly vinyl chloride (PVC), degrading bacteria’s were isolate and characterize from soil dumped with plastics. The PVC degradating bacterial were identified as E.Coli, Staphylococcus, Pseudomonas and Klebsiella. It was observed that maximum degradation by Pseudomonas and degradation after 10 months was 40.53%, 23.06%, 10.92% and 5.32% for Pseudomonas, Klebsiella, Staphylococcus and E.Coli respectively.This work concluded that soil contains bacteria’s that have ability to carry degradation of poly vinyl chloride (PVC)
Effect of primary packaging on microbiological status of oral solid dosage form Khanna, Meenal; Teotia, U. V. S; Singh, Yogendra
Journal of Applied Pharmaceutical Research Vol 6 No 1 (2018)
Publisher : Creative Pharma Assent

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18231/2348-0335.2018.0001

Abstract

The emergence of microbial contaminants in non-sterile drugs caused not only the degradation of many products, but also proved to be a potential risk to consumer health. The aim of this study was to test microbial load of non sterile solid pharmaceutical product and investigate the effects of different packaging system on microbial status of pharmaceutical product. A total of 18 sample of solid dosage form packaged in different packaging were procured from market. All samples have been tested for the presence of specific microorganisms, Total aerobic microbial counts (TAMC) and Total yeast and mold counts (TYMC) using compendial procedures. Out of 18 sample 72.22 % (n=13) had shown microbial growth and only 16 % (n=3) of samples were non-compliant. Sample containing herbal ingredients, were the most heavily contaminated, showing a bacterial load > 104 CFU/g. The result showed that all the tested samples were free from E. coli. There was no significant difference (p>0.05) in microbial load of product packaged in different primary packaging.
Screening of poly vinyl chloride degrading bacteria from plastic contaminated area of Baddi Kumar, Sahni; Teotia, U. V. S; Singh, Yogendra
Journal of Applied Pharmaceutical Research Vol. 5 No. 3 (2017)
Publisher : Creative Pharma Assent

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (374.655 KB) | DOI: 10.18231/2348-0335.2017.0005

Abstract

Plastic wastes are posing ever increasing environmental concerns. Recent research works have shown that most of the constituents of plastics can be degraded by microbes and the film plastics can be treated by microbial systems. In this study, poly vinyl chloride (PVC), degrading bacteria’s were isolate and characterize from soil dumped with plastics. The PVC degradating bacterial were identified as E.Coli, Staphylococcus, Pseudomonas and Klebsiella. It was observed that maximum degradation by Pseudomonas and degradation after 10 months was 40.53%, 23.06%, 10.92% and 5.32% for Pseudomonas, Klebsiella, Staphylococcus and E.Coli respectively.This work concluded that soil contains bacteria’s that have ability to carry degradation of poly vinyl chloride (PVC)
A comprehensive review on microbial degradation of plastic waste Kumar, Sahni; Teotia, U. V. S; Singh, Yogendra
Journal of Applied Pharmaceutical Research Vol. 5 No. 4 (2017)
Publisher : Creative Pharma Assent

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (261.017 KB) | DOI: 10.18231/2348-0335.2017.0009

Abstract

Plastic is a broad name given to different polymers with high molecular weight, which can be degraded by various processes. However, considering their abundance in the environment and their specificity in attacking plastics, biodegradation of plastics by microorganisms and enzymes seems to be the most effective process. When plastics are used as substrates for microorganisms, evaluation of their biodegradability should not only be based on their chemical structure, but also on their physical properties (melting point, glass transition temperature, crystallinity, storage modulus etc.). In this review, microbial and enzymatic biodegradation of plastics and some factors that affect their biodegradability are discussed. Plastics have become an important part of modern life and are used in different sectors of applications like packaging, building materials, consumer products and much more. Each year about 100 million tons of plastics are produced worldwide. Degradation is defined as reduction in the molecular weight of the polymer. The Degradation types are (a). Chain end degradation/de-polymerization (b).Random degradation/reverse of the poly condensation process. Biodegradation is defined as reduction in the molecular weight by naturally occurring microorganisms such as bacteria, fungi, and actinomycetes. That is involved in the degradation of both natural and synthetic plastics.
Examining the Specificity of Smartphone ECG Devices in Decision-Making for ST-Elevation Myocardial Infarction and Non-ST-Elevation Myocardial Infarction mahajan, Sahil; Garg, Salil; Singh, Yogendra; sharma, richa; Bhatia, Tanuj; chandola, nitin; agarwal, deeksha
Jurnal Kardiologi Indonesia Vol 45 No 3 (2024): July - September, 2024
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1740

Abstract

Background & Objectives: Electrocardiography (ECG) stands as a cornerstone diagnostic tool for assessing cardiac health, particularly in ruling out abnormalities. The integration of smartphone devices presents a promising avenue for expedited detection of cardiac irregularities. This study aims to evaluate the diagnostic efficacy of smartphone ECG devices in subjects admitted to Cardiac Care Units (CCUs) and Cardiac Intensive Care Units (CICUs). Methods: A retrospective analysis was conducted on a cohort comprising 62 patients presenting with cardiac symptoms. Utilizing smartphone ECG devices as the index, 12-lead ECG tests were administered alongside the Gold Standard ECG machine for comparison among patients in CCUs and CICUs. Diagnostic decisions concerning the presence of ST-Elevation Myocardial Infarction (STEMI) or Non-ST-Elevation Myocardial Infarction (NSTEMI) were made by a team of cardiologists following a meticulous review of both sets of ECG reports. Results: Data analysis was conducted on 56 patients. The smartphone-based ECG device exhibited 100% specificity, 93% sensitivity, 80% Negative Predictive Value, and 100% Positive Predictive Value, yielding an F-score of 0.96 and a Mathew Correlation Coefficient value of 0.86. Discussions: This study unequivocally underscores the significant potential of the Spandan ECG device in accurately identifying a range of cardiac abnormalities, including critical conditions such as STEMI and ischemia. Despite its portable nature, smartphone ECG technology demonstrates utility within Critical Care Units for timely monitoring and diagnosis.
Co-Authors agarwal, deeksha Bhatia, Tanuj chandola, nitin Garg, Salil Khanna, Meenal mahajan, Sahil Richa Sharma Sahni Kumar, Sahni Teotia, U. V. S Teotia, U. V. S U.V.S Teotia, U.V.S UVS Teotia, UVS