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All Journal Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal MAHESA : Malahayati Health Student Journal
Indry Salonika Sutiawan
Fakultas Kedokteran, Universitas Udayana
Dentistry Education Health Professions Nursing Public Health Veterinary

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Morbus Hansen Tipe Lepromatosa dengan Eritema Nodosum Leprosum Berat dan Cacat Kusta Tingkat Dua Luh Made Mas Rusyati; Indry Salonika Sutiawan
Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Vol 14 No 1 (2024): Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal: Januari 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32583/pskm.v14i1.1327

Abstract

Kusta merupakan penyakit yang menular dan menyebabkan masalah yang sangat kompleks di Indonesia, dimana mempengaruhi masalah medis, sosial, ekonomi, budaya, dan keamanan nasional. Tujuan: laporan kasus ini bertujuan untuk mengetahui perkembangan kasus Morbus Hansen tipe Lepramatosa dengan Eritema Nodosum Leprosum barta dan Cacat Kusta Tingkat Dua pada pasien laki-laki usia 40 tahun. Metode: Laporan kasus ini menggunakan metode kualitatif dengan pendekatan observasi dengan pemeriksaan fisik serta penunjang.Hasil: Diagnosis ditegakkan berdasarkan anamnesis adanya bercak-bercak berwarna putih pada hampir seluruh tubuh. Pada pemeriksaan fisik didapatkan benjolan kemerahan pada seluruh tubuh, disertai demam dan nyeri persendian. Status dermatologis pada regio fasialis tampak wajah yang berkerut dan berlipat dengan gambaran fasies leonina, madarosis pada alis mata kanan dan kiri, adanya infiltrat pada kedua cuping telinga, dan didapatkan efloresensi nodul eritema-hiperpigmentasi multipel, bentuk bulat, ukuran diameter 0,8 – 1,2 cm, tersebar diskret, konsistensi padat dan lunak, immobile, permukaan rata, nyeri tekan (+). Tatalaksana yang diberikan kepada pasien adalah metilprednisolon 16 miligram tablet tiap 8 jam intraoral, parasetamol 1000 miligram tiap 8 jam intraoral, vitamin B1B6B12 1 tablet tiap 24 jam intraoral, kompres NaCl 0,9% selama 10-15 menit tiap 8 jam topikal pada ulkus, dan natrium fusidat 2% krim tiap 12 jam topikal pada ulkus.
Low Serum Vitamin E Levels Positively Correlate with the Severity of Acne Vulgaris Indry Salonika Sutiawan; Ketut Kwartantaya Winaya; Nyoman Suryawati; Luh Made Mas Rusyati; I Gusti Ayu Agung Dwi Karmila; Ni Made Dwi Puspawati
MAHESA : Malahayati Health Student Journal Vol 4, No 10 (2024): Volume 4 Nomor 10 (2024)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v4i10.15882

Abstract

ABSTRACT Acne vulgaris (AV) is a common disorder of the pilosebaceous, especially prevalent in adolescents. Acne vulgaris ranks among the top ten most prevalent diseases globally. Although AV may resolve spontaneously, sequelae such as scar formation can persist, causing aesthetic and psychological disturbances. There is an antioxidant to counteract acne-causing oxidative stress, vitamin E, which is an important antioxidant in the human body. Therefore, vitamin E in the skin can reduce the formation of squalene peroxide and prevent the occurrence of AV. This is an analytical observational study using a cross-sectional design. The investigation was conducted at the Dermatology and Venereology Clinic of Prof. Dr. I.G.N.G. Ngoerah Denpasar Hospital and the laboratory of the Faculty of Medicine, Udayana University, from February 2024 until the sample size was fulfilled. The sample consisted of patients aged 12-45 years with acne vulgaris who visited the clinic and were then selected through consecutive sampling according to the inclusion and exclusion criteria. In the non-AV group, the mean serum vitamin E level was 19.3 ± 0.99 µg/ml, whereas in the AV group, it was 4.49 ± 19.1 µg/ml, indicating a significant variance. There was a positive correlation between low vitamin E levels and the severity of AV. The linearity graph shows the direction of the relationship between serum vitamin E levels and the severity of AV, which leads to the lower right, indicating that the higher the severity of AV, the lower the serum vitamin E levels. The mean levels differed significantly between the non-AV and AV groups. A favorable association was found between low vitamin E levels and the severity of AV. Keywords: Acne Vulgaris, Severity, Serum Vitamin E, Reactive Oxygen Species (ROS)
Co-Authors I Gusti Ayu Agung Dwi Karmila Ketut Kwartantaya Winaya Luh Made Mas Rusyati Ni Made Dwi Puspawati Nyoman Suryawati