Article Per Year (5 Year)
p-Index From 2021 - 2026
0.882
P-Index
This Author published in this journals
All Journal Indonesian Journal of Pharmaceutical Science and Technology Lumbung Farmasi : Jurnal Ilmu Kefarmasian Medical Sains : Jurnal Ilmiah Kefarmasian Medical Sains : Jurnal Ilmiah Kefarmasian
Tubagus Akmal
Akademi Farmasi Bumi Siliwangi
Computer Science & IT Health Professions Medicine & Pharmacology

Published : 5 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 5 Documents
Search

 1 
Formulation of Peel-off Gel Face Mask from Pandanus amaryllifolius (Roxb.) Leaves Extract Tubagus Akmal; Yenni P. Tanjung; Sofa P. Nurlaela
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 4, No. 1 (2022)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v1i1.43015

Abstract

UV exposure is the most significant environmental risk factor that can be altered for skin cancer andmany other skin conditions. An antioxidant is a compound that can protect the skin from sun radiation.Pandanus amaryllifolius is a plant that has antioxidant activity because it contains polyphenols. Theobjective of this study is to formulate a pandan Wangi leaf extract peel-off gel facial mask and analyzehow variations in the extract's concentration affect the physical and chemical evaluation. In this study,three formulas were made with varying concentrations of extract, namely F1 (1%), F2 (3%), and F3(5%). The preparation was evaluated for 28 days at a controlled room temperature (180C-300C+20C).The evaluation carried out included a physical evaluation (organoleptic, spreadability, homogeneity,viscosity, dry time) and a chemical evaluation (pH). The results showed that F1, F2, and F3 met therequirements for physical and chemical evaluation. Variations in the concentration of Pandan Wangileaf extract had a significant effect (p<0.05) on the results of the preparation evaluation which includedorganoleptic, spreadability, and viscosity. While for the evaluation of homogeneity, dry time, and pHdid not show significant results (p> 0.05). These results indicate that pandanus leaf extract (Pandanusamaryllifolius Roxb.) can be formulated into a peel-off gel facial mask.
Formulation of Blush On Cream from Hibiscus Sabdariffa (L.) Flower Extract Tubagus Akmal; Yenni P. Tanjung; Yudhea Afrizki
Indonesian Journal of Pharmaceutical Science and Technology Vol 10, No 2 (2023)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v10i2.41875

Abstract

Natural dyes have become more popular as a result of the harmful and carcinogenic effects of syntheticdyes. Anthocyanins are natural dyes that are widely used to replace synthetic dyes and can also act asantioxidants that can be found in rosella (Hibiscus sabdarrifa L.). This study aimed to obtain blushon cream from rosella flower extract (RFE) with olive oil and to determine the effect of olive oilconcentration on the evaluation results. The blush on cream was made in 3 formula, F1 (13,5%),F2 (15,5%), and F3 (17,5%). The cream was evaluated for 28 days in room temperature (15–30⁰C)which included organoleptic, pH, homogeneity, spreadability, adhesion, cream type, and viscosity.The results of the evaluation of RFE blush on cream with olive oil showed that F1, F2, and F3 metthe requirements for evaluating the preparation for organoleptic tests, pH, homogeneity, spreadability,adhesion, cream type, and viscosity. Variations concentration of olive oil gave no significant effect(p>0,05) on the organoleptic, pH, homogeneity, spreadability, and cream type and had significant effect(p<0,05) on the adhesion and viscosity test. The findings demonstrate that RFE can be made in blushon cream formulations with olive oil as emollients.
Formulasi Dan Evaluasi Sediaan Lip cream Ekstrak Ubi Jalar Ungu (Ipomea batatas L.) Tubagus Akmal; Yenni Puspita Tanjung; Nurul Fauziah
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 4, No 2 (2023): Juli
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v4i2.12985

Abstract

Saat ini dipasaran masih terdapat kosmetik dekoratif yang menggunakan pewarna sintetik berbahaya. Sedangkan dalam kosmetik dekoratif warna merupakan bagian terpenting. Pigmen antosianin dalam ekstrak ubi jalar ungu (Ipomea batatas L.) dapat digunakan sebagai pengganti pewarna sintetik pada kosmetik, salah satunya sediaan lip cream. Penelitian ini bertujuan untuk mengetahui formula lip cream dengan pewarna alami ekstrak ubi jalar ungu yang memenuhi syarat evaluasi sediaan dan mempelajari pengaruh variasi konsentrasi ekstrak ubi jalar ungu dalam formula terhadap hasil evaluasi lip cream. Ekstrak ubi jalar ungu sebagai pewarna alami di formulasikan dengan varian konsentrasi yaitu FI (10%), FII (15%), dan FIII (20%). Evaluasi sediaan lip cream meliputi uji organoleptis, uji homogenitas, uji viskositas, uji daya sebar, uji daya lekat, dan uji pH. Evaluasi dilakukan selama 28 hari pada suhu ruang (15-30̊C). FI dan FII memenuhi persyaratan uji organoleptis, homogenitas, viskositas, daya sebar, daya lekat, dan pH. Sedangkan FIII hanya memenuhi syarat uji organoleptis, homogenitas, viskositas, daya lekat dan pH. Pada hasil analisis statistik variasi konsentrasi ekstrak ubi jalar ungu sebagai pewarna alami memberikan hasil berbeda bermakna (p<0,05) terhadap uji organoleptis, viskositas, daya sebar dan juga daya lekat. Sedangkan terhadap uji homogenitas dan pH yang diperoleh hasil tidak berbeda bermakna (p>0,05).
INFLUENCE OF Momordica charantia (L.) ON THE PHARMACOKINETICS AND PHARMACODYNAMICS OF GLICLAZIDE IN ALLOXAN-INDUCED DIABETIC RATS Tubagus Akmal; Lucy Sasongko
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 3 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i3.854

Abstract

Diabetes mellitus is a metabolic disorder present in the top ten diseases that cause death. Diabetes treatment usually uses conventional drugs, such as gliclazide, which is the first choice in patients with type 2 diabetes mellitus who are intolerant to metformin. In addition to conventional medicine, herbal medicines are in great demand and have become a focus of research to obtain an alternative treatment for type 2 diabetes mellitus. One herb that has been widely used and studied is the bitter melon. This study aimed to determine the effects of bitter melon extract (BME) on the pharmacokinetics and pharmacodynamics of gliclazide when used simultaneously. The study was conducted on three groups of rats with alloxan-induced diabetes. Group 1 received a single dose of gliclazide (33 mg/kg BW, n = 3), group 2 received aqueous extracts of bitter melon fruit (341 mg/kg BW, n = 4), and group 3 received a combination of gliclazide and an aqueous extract of bitter melon (n = 4). The pharmacokinetic profile of gliclazide is affected by BME, where interactions occur during the absorption phase. The blood glucose levels were measured using a glucometer. Decreased blood glucose levels following administration of gliclazide, extract of bitter melon, and a combination of gliclazide and extract of bitter melon 6 hours after dosing were 74.73%, 82.977%, and 86.457%, respectively. This study demonstrated the interactions between gliclazide and BME in the absorption phase of gliclazide and its effect on blood glucose levels.
INFLUENCE OF Momordica charantia (L.) ON THE PHARMACOKINETICS AND PHARMACODYNAMICS OF GLICLAZIDE IN ALLOXAN-INDUCED DIABETIC RATS Tubagus Akmal; Lucy Sasongko
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 3 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i3.854

Abstract

Diabetes mellitus is a metabolic disorder present in the top ten diseases that cause death. Diabetes treatment usually uses conventional drugs, such as gliclazide, which is the first choice in patients with type 2 diabetes mellitus who are intolerant to metformin. In addition to conventional medicine, herbal medicines are in great demand and have become a focus of research to obtain an alternative treatment for type 2 diabetes mellitus. One herb that has been widely used and studied is the bitter melon. This study aimed to determine the effects of bitter melon extract (BME) on the pharmacokinetics and pharmacodynamics of gliclazide when used simultaneously. The study was conducted on three groups of rats with alloxan-induced diabetes. Group 1 received a single dose of gliclazide (33 mg/kg BW, n = 3), group 2 received aqueous extracts of bitter melon fruit (341 mg/kg BW, n = 4), and group 3 received a combination of gliclazide and an aqueous extract of bitter melon (n = 4). The pharmacokinetic profile of gliclazide is affected by BME, where interactions occur during the absorption phase. The blood glucose levels were measured using a glucometer. Decreased blood glucose levels following administration of gliclazide, extract of bitter melon, and a combination of gliclazide and extract of bitter melon 6 hours after dosing were 74.73%, 82.977%, and 86.457%, respectively. This study demonstrated the interactions between gliclazide and BME in the absorption phase of gliclazide and its effect on blood glucose levels.
Co-Authors Lucy Sasongko Nurul Fauziah Sofa P. Nurlaela Yenni P. Tanjung Yenni Puspita Tanjung Yudhea Afrizki