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All Journal Journal of Biomedicine and Translational Research
Miftahuz Zakiyah
Faculty of Medicine, Universitas Indonesia
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

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Mechanism of Immune System Dysfunction, Apoptosis and Oxidative Stress on Endometriosis Miftahuz Zakiyah; Asmarinah Asmarinah
Journal of Biomedicine and Translational Research Vol 9, No 2 (2023): August 2023
Publisher : Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jbtr.v9i2.16885

Abstract

Endometriosis is gynecology disease that still needs advance knowledge to develop best treatment for enhancing  the best quality of patient life. It is characterized by forming the endometrium tissue outside the uterus and happened approximately in 5-10% of reproductive women. Endometriosis with poor prognosis can be a high risk of endometrium cancer, ovarian cancer and results in infertility. A deep attempt to reach the knowledge of clear molecular etiology of endometriosis is needed. Here, there are three molecular mechanism dysfunction that occurs on endometriosis; (1) immune system dysfunction, (2) disturbance in apoptosis signal, (3) and oxidative stress elevation. Therefore, the determination of molecular pathogenesis of endometriosis will be useful in developing of diagnostic and therapeutic methods.
Co-Authors Asmarinah Asmarinah