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All Journal JURNAL ILMIAH KESEHATAN MASYARAKAT DAN SOSIAL JUKEJ: Jurnal Kesehatan Jompa
Nazula Rahma Shafriani
Universitas Aisyiyah Yogyakarta
Education Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Hubungan Tingkat Kepatuhan Terapi ARV dengan Kadar Viral Load pada Pasien HIV di Puskesmas Gedongtengen Yogyakarta: Studi Cross-Sectional Nadia Budi Kusuma Wardani; Farida Noor Irfani; Nazula Rahma Shafriani
JUKEJ : Jurnal Kesehatan Jompa Vol 5 No 3 (2026): JUKEJ: Jurnal Kesehatan Jompa
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jkj.Vol5.Iss3.2932

Abstract

Human Immunodeficiency Virus (HIV) attacks the immune system, causing a decline in immune function and potentially progressing to Acquired Immunodeficiency Syndrome (AIDS). Viral load testing is used to assess the amount of virus present in the blood and evaluate the effectiveness of treatment, while antiretroviral (ARV) therapy functions to suppress viral replication and improve immune function. This study aimed to analyze the relationship between viral load levels and adherence to ARV therapy among HIV patients at Puskesmas (Community Health Center) Gedongtengen, Yogyakarta. This study was an analytical observational study with a cross-sectional approach. Samples were selected using a total sampling technique, involving 34 respondents. Data were collected through questionnaires and medical records from December 2025 to January 2026. The results showed a significant relationship between viral load levels and adherence to ARV therapy (p = 0.000), indicating that patients with high adherence had undetectable or lower viral load levels compared to non-adherent patients. In conclusion, adherence to ARV therapy plays an important role in suppressing viral replication, maintaining low viral load levels, and improving treatment outcomes as well as patients’ quality of life.
Hubungan Kadar C- Reactive Protein (CRP) dan Profil Leukosit pada Pasien Sepsis Neonatorum Bayi di Rumah Sakit PKU Muhammadiyah Yogyakarta Nizma Hartin Ferawati; Farida Noor Irfani; Nazula Rahma Shafriani
JURNAL ILMIAH KESEHATAN MASYARAKAT DAN SOSIAL Vol. 4 No. 3 (2026): Agustus : JURNAL ILMIAH KESEHATAN MASYARAKAT DAN SOSIAL
Publisher : CV. ALIM'SPUBLISHING

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/jikas.v4i3.1863

Abstract

Neonatal sepsis is a major factor contributing to morbidity and mortality in newborns. C-Reactive Protein (CRP) and leukocytes are laboratory tests used as indicators of inflammation. This study aims to determine the relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients. The research method used was an observational analytic with a cross-sectional approach. Neonatal sepsis at PKU Muhammadiyah Yogyakarta in the period 2021-2026 consisted of 30 samples using a total sampling technique. The distribution of respondents was dominated by male gender compared to female gender, who had a low birth weight <2,500 grams. Based on the study, normal CRP levels were found in 21 respondents, which was caused by a delay in increasing CRP levels. Leukocytes had high levels in 18 respondents. Leukocytes are an initial phase of examination in detecting inflammation that does not require a long time, have several different morphological types in detecting inflammation in the body. This study shows that the most dominant increase in leukocyte levels is found in eosinophils and neutrophils. Based on medical record data at PKU Muhammadiyah Hospital Yogyakarta, analysis using the Spearman correlation test yielded a correlation coefficient of 0.261 with a significance value of 0.164 (p > 0.05). The results showed no significant relationship between the studied variables, with a positive direction and weak correlation strength. The conclusion of this study is that there is no significant relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients.
Co-Authors Farida Noor Irfani Nadia Budi Kusuma Wardani Nizma Hartin Ferawati